EFSA Compendium of Botanicals

Draft - work in progress

Gymnosporia senegalensis (Lam.) Loes. // Maytenus senegalensis (Lam.) Exell

Family:: Celastraceae
Approval state:: Approved
Number of articles retrieved:: 174
Number of processed references:: 4

Compositions

#1: tannins in bark #2: alkaloids in bark #3: saponins in bark #4: gallotannins in roots #5: stachydrine in roots #6: gallocathechin in leaves #7: epigallocathechin in leaves

Endpoint Studies

Genotoxicity

Composition #1: Mann, Abdulahi., Roheem, Fatimah Opeyemi., Saidu, Abubakar N., Yisa, Jonathan., Fadipe, Labake A., Ogbadoyi, Emmanuel O. Assessment of phytoconstituents and antidiabetic activity of the crude extract and partitioned fractions of Maytenus senegalensis (Lam.) exell (Celastraceae) root bark. international research journal of pure and applied chemistry, 2014, vol. 4, no. 6), 746-76, p. 16 pp. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol in root bark
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins in bark

Composition #2: Mann, Abdulahi., Roheem, Fatimah Opeyemi., Saidu, Abubakar N., Yisa, Jonathan., Fadipe, Labake A., Ogbadoyi, Emmanuel O. Assessment of phytoconstituents and antidiabetic activity of the crude extract and partitioned fractions of Maytenus senegalensis (Lam.) exell (Celastraceae) root bark. international research journal of pure and applied chemistry, 2014, vol. 4, no. 6), 746-76, p. 16 pp. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol in root bark
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids in bark

Composition #3: Mann, Abdulahi., Roheem, Fatimah Opeyemi., Saidu, Abubakar N., Yisa, Jonathan., Fadipe, Labake A., Ogbadoyi, Emmanuel O. Assessment of phytoconstituents and antidiabetic activity of the crude extract and partitioned fractions of Maytenus senegalensis (Lam.) exell (Celastraceae) root bark. international research journal of pure and applied chemistry, 2014, vol. 4, no. 6), 746-76, p. 16 pp. .

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol in root bark
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins in bark

Composition #4: Mulaudzi, R.B., Ndhlala, A.R., Kulkarni, M.G., Van Staden, J. Pharmacological properties and protein binding capacity of phenolic extracts of some Venda medicinal plants used against cough and fever. journal of ethnopharmacology, 2012, vol. 143, no. 1, p. 185–193. DOI: 10.1016/j.jep.2012.06.022. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Gallotannins (RF-00013316-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

rhodanine assay
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.2
Internal remarks:

gallotannins in roots

Composition #5: Pistelli, L., Venturi, R., Marsili, A., Morelli, I. Alkaloids and coumarins from Gymnosporia senegalensis var. Spinosa (Celastraceae) . biochemical systematics and ecology, 1998, vol. 26, no. 6, p. 677–679. DOI: 10.1016/S0305-1978(97)00128-2. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

stachydrine (RF-00004062-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

stachydrine in roots

Composition #6: Okoye, Festus Basden Chiedu., Debbab, Abdessamad., Wray, Victor., Esimone, Charles Okechukwu., Osadebe, Patience Ogoamaka., Proksch, Peter. A phenyldilactone, bisnorsesquiterpene, and cytotoxic phenolics from Maytenus senegalensis leaves . tetrahedron letters, 2014, vol. 55, no. 28, p. 3756–3760. DOI: 10.1016/j.tetlet.2014.05.058. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

gallocatechin (RF-00003822-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, chromatography, HPLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

gallocathechin in leaves

Composition #7: Okoye, Festus Basden Chiedu., Debbab, Abdessamad., Wray, Victor., Esimone, Charles Okechukwu., Osadebe, Patience Ogoamaka., Proksch, Peter. A phenyldilactone, bisnorsesquiterpene, and cytotoxic phenolics from Maytenus senegalensis leaves . tetrahedron letters, 2014, vol. 55, no. 28, p. 3756–3760. DOI: 10.1016/j.tetlet.2014.05.058. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

epigallocatechins (RF-00010812-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

NMR, chromatography, HPLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

epigallocathechin in leaves