EFSA
ecomole
vscht
  2. Frangula alnus Mill. // Rhamnus frangula L.

Frangula alnus Mill. // Rhamnus frangula L.

Family:
Rhamnaceae
Approval state:
Approved
Number of articles retrieved:
754
Number of processed references:
4
Compositions
#1: Quinoline alkaloids (bark) #2: Benzophenantridine alkaloids (bark) #3: Emodin (bark) #4: Chrysophanol (bark) #5: Physcione (bark) #6: Frangulin A (bark) #7: Frangula emodin (bark) #8: Rhein (bark) #9: Glucofrangulin A (bark) #10: chrysophanol (bark) #11: emodin (bark) #12: physcion (bark)
Endpoint Studies
Genotoxicity
#1: Emodin from the bark extract at 200 μg/ml induced a significant increase in DNA damage in human peripheral blood lymphocytes
Composition #1: Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. drug testing and analysis, 2017, p. Ahead of Print. .
Composition #2: Nardin, Tiziana., Piasentier, Edi., Barnaba, Chiara., Larcher, Roberto. Alkaloid profiling of herbal drugs using high resolution mass spectrometry. drug testing and analysis, 2017, p. Ahead of Print. .
Composition #3: Goncalves, Renato Sonchini., Silva, Expedito Leite., Hioka, Noboru., Nakamura, Celso Vataru., Bruschi, Marcos Luciano., Caetano, Wilker. An optimized protocol for anthraquinones isolation from Rhamnus frangula L. . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1356836. [DOI link]
Composition #4: Goncalves, Renato Sonchini., Silva, Expedito Leite., Hioka, Noboru., Nakamura, Celso Vataru., Bruschi, Marcos Luciano., Caetano, Wilker. An optimized protocol for anthraquinones isolation from Rhamnus frangula L. . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1356836. [DOI link]
Composition #5: Goncalves, Renato Sonchini., Silva, Expedito Leite., Hioka, Noboru., Nakamura, Celso Vataru., Bruschi, Marcos Luciano., Caetano, Wilker. An optimized protocol for anthraquinones isolation from Rhamnus frangula L. . natural product research, 2017, p. 1–4. DOI: 10.1080/14786419.2017.1356836. [DOI link]
Composition #6: Godard, Sophie., Slacanin, Ivan., Viret, Olivier., Gindro, Katia. Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew . plant physiology and biochemistry, 2009, vol. 47, no. 9, p. 827–837. DOI: 10.1016/j.plaphy.2009.04.003. [DOI link]
Composition #7: Godard, Sophie., Slacanin, Ivan., Viret, Olivier., Gindro, Katia. Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew . plant physiology and biochemistry, 2009, vol. 47, no. 9, p. 827–837. DOI: 10.1016/j.plaphy.2009.04.003. [DOI link]
Composition #8: Godard, Sophie., Slacanin, Ivan., Viret, Olivier., Gindro, Katia. Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew . plant physiology and biochemistry, 2009, vol. 47, no. 9, p. 827–837. DOI: 10.1016/j.plaphy.2009.04.003. [DOI link]
Composition #9: Godard, Sophie., Slacanin, Ivan., Viret, Olivier., Gindro, Katia. Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew . plant physiology and biochemistry, 2009, vol. 47, no. 9, p. 827–837. DOI: 10.1016/j.plaphy.2009.04.003. [DOI link]
Composition #10: Brkanac, Sandra Radic., Genic, Marko., Gajski, Goran., Vujcic, Valerija., Garaj-Vrhovac, Vera., Kremer, Dario., Domijan, Ana-Marija. Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin . regulatory toxicology and pharmacology, 2015, vol. 73, no. 3, p. 923–929. DOI: 10.1016/j.yrtph.2015.09.025. [DOI link]
Composition #11: Brkanac, Sandra Radic., Genic, Marko., Gajski, Goran., Vujcic, Valerija., Garaj-Vrhovac, Vera., Kremer, Dario., Domijan, Ana-Marija. Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin . regulatory toxicology and pharmacology, 2015, vol. 73, no. 3, p. 923–929. DOI: 10.1016/j.yrtph.2015.09.025. [DOI link]
Composition #12: Brkanac, Sandra Radic., Genic, Marko., Gajski, Goran., Vujcic, Valerija., Garaj-Vrhovac, Vera., Kremer, Dario., Domijan, Ana-Marija. Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin . regulatory toxicology and pharmacology, 2015, vol. 73, no. 3, p. 923–929. DOI: 10.1016/j.yrtph.2015.09.025. [DOI link]
Genotox #1: Brkanac, Sandra Radic., Genic, Marko., Gajski, Goran., Vujcic, Valerija., Garaj-Vrhovac, Vera., Kremer, Dario., Domijan, Ana-Marija. Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its active component emodin . regulatory toxicology and pharmacology, 2015, vol. 73, no. 3, p. 923–929. DOI: 10.1016/j.yrtph.2015.09.025. [DOI link]