EFSA
ecomole
vscht
  2. Excoecaria agallocha L.

Excoecaria agallocha L.

Family:
Euphorbiaceae
Approval state:
Approved
Number of articles retrieved:
554
Number of processed references:
15
Compositions
#1: Taraxerol (stems) #2: pentacyclic triterpenic derivatives (epitaraxerol, taraxeryl acetate) in leaves #3: 10 % tannins in the bark #4: Pentacyclic triterpenic derivatives (3-​Oxomanoyl oxide, friedelin, β-​amyrin, epi-​β-​amyrin friedelan-​3β-​ol, taraxerol, friedalan-​3α-​ol, 3β-​acetoxytaraxer-​14-​en-​28-​oic acid) in stem #5: pentacyclic triterpenic derivatives (epitaraxerol, epi-​β-​amyrin, epi-​α-​amyrin, epilupeol, betulin, betulinic acid, betulone, betulonic acid, lupenon, (9Z,​12Z,​15Z)​-​2,​3-​dihydroxypropyl octadecatrienoate​, and (9Z,​12Z)​-​2,​3-​dihydroxypropyl octadecadienoate) in stem #6: diterpenes (excoagallochaol A) in stem #7: Pentacyclic triterpenic derivatives (taraxerol, taraxerone) in leaves #8: Pentacyclic triterpene derivatives (14-taraxeren-3-one, 18-oleanen-3-one, 3, 28-dihydroxyl-lupeol, 28-hydroxy-20(29)-lupen-3-one, 18-oleanen-3-ol ) #9: dieterpenes (ent-16-hydroxy-3-oxo-13-epi-manoylolid, (13R,14R)-ent-8 alpha,13;14,15-diepoxy-13-epi-labda-3 beta-ol, ent-3 beta-hydroxy-15-beyeren-2-one, ent-15-hydroxy-labda-8(17),13E-dien-3-one ) in wood #10: Labdane terpenes (excoecarin F, excoecarin G1, excoecarin G2) in wood #11: Beyren diterpenoid derivative: ent-3beta-Hydroxy-15-beyeren-2-one (wood) #12: Diterpenes (Excoecarin K, excoecarin D, excoecarin E, stachenol, stachenone) in wood #13: Diterpenes (excoecarin M and excoecarin N) in wood #14: Kaurane diterpenoid derivative: ent-kauran-16â-ol-3-one (roots) #15: diterpenes (agallochin F, G, H, I) in roots #16: Beyerane diterpenoid derivative: 2-acetoxy-1,15-beyeradiene-3,12-dione (roots) #17: diterpenes (Excoecarin V1, Excoecarin V2 methyl ester, Excoecarin V3) in stem #18: diterpenes (agallochin H and agallochin H, ent-12-oxo-2,3-secobeyer-15-ene-2,3-dioic acid) in wood #19: labdane diterpenes (excoecarin S, excoecarin T1, excoecarin T1 demethyl ester, excoecarin T2, excoecarin T2 diemethyl ester) in wood #20: phorbol ester (12-Deoxyphorbol 13-(3E, 5E-decadienoate) in leaves, stems and bark #21: excoecarins (excoecarin A, B and C) in wood
Endpoint Studies
Genotoxicity
Composition #1: Hui, W. H., Sung, M. L. An examination of the Euphorbiaceae of Hong Kong. II. The occurrence of epitaraxerol and other triterpenoids. australian journal of chemistry, 1968, vol. 21, no. 8, p. 2137–40. .
Composition #2: Hui, W. H., Sung, M. L. An examination of the Euphorbiaceae of Hong Kong. II. The occurrence of epitaraxerol and other triterpenoids. australian journal of chemistry, 1968, vol. 21, no. 8, p. 2137–40. .
Composition #3: Hoque, Muzzammel. Utilization of bark tannins from Excoecaria agallocha Linn. bangladesh journal of scientific and industrial research, 1982, vol. 17(1-2), p. 70–9. .
Composition #4: Anjaneyulu, V., Babu, J. Suresh., Babu, B. Hari., Reddy, M. Venkata. Terpenoids from a mangrove, Excoecaria agallocha.. acta ciencia indica, chemistry, 1993, vol. 19, no. 4, p. 123–6. .
Composition #5: Liu, Zhen., Jiang, Wei., Deng, Zhi-Wei., Lin, Wen-Han. Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L. journal of chinese pharmaceutical sciences, 2010, vol. 19, no. 5, p. 387–392. .
Composition #6: Liu, Zhen., Jiang, Wei., Deng, Zhi-Wei., Lin, Wen-Han. Assignment of the absolute stereochemistry of an unusual diterpenoid from the mangrove plant Excoecaria agallocha L. journal of chinese pharmaceutical sciences, 2010, vol. 19, no. 5, p. 387–392. .
Composition #7: Santhanam, Satyan Ramachandran., Subramanian, Malarvannan., Egigu, Meseret C., Parida, Ajay. Pentacyclic triterpenoids and a linear alkane from the milky mangrove tree (Excoecaria agallocha L.) are toxic to the larva of Helicoverpa armigera Hubner. (Lepidoptera: Noctuidae). international journal of advanced research, 2014, vol. 2, no. 6), 1-1, p. 12 pp. .
Composition #8: Li Xiang., Yao Yan-Hua., Zheng Yi-Nan., Lin Wen-Han., Deng Zhi-Wei. Chemical constituents of mangrove plant Excoecaria agallocha. chinese journal of natural medicines, 2006, vol. 4, no. 3, p. 188–191. .
Composition #9: Konishi, T., Takasaki, M., Tokuda, H., Kiyosawa, S., Konoshima, T. Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha. biological & pharmaceutical bulletin, 1998, vol. 21, no. 9, p. 993–996. .
Composition #10: Konishi, T., Konoshima, T., Fujiwara, Y., Kiyosawa, S., Miyahara, K., Nishi, M. Stereostructures of new labdane-type diterpenes, excoecarins F, G1, and G2 from the wood of Excoecaria agallocha . chemical & pharmaceutical bulletin, 1999, vol. 47, no. 3, p. 456–458. .
Composition #11: Konishi, T., Konoshima, T., Fujiwara, Y., Kiyosawa, S. Excoecarins D, E, and K, from Excoecaria agallocha. journal of natural products, 2000, vol. 63, no. 3, p. 344–346. DOI: 10.1021/np990366t. [DOI link]
Composition #12: Konishi, T., Konoshima, T., Fujiwara, Y., Kiyosawa, S. Excoecarins D, E, and K, from Excoecaria agallocha. journal of natural products, 2000, vol. 63, no. 3, p. 344–346. DOI: 10.1021/np990366t. [DOI link]
Composition #13: Konishi, T., Konoshima, T., Maoka, T., Fujiwara, Y. Novel diterpenes, excoecarins M and N from the resinous wood of Excoecaria agallocha . tetrahedron letters, 2000, vol. 41, no. 18, p. 3419–3422. DOI: 10.1016/S0040-4039(00)00391-9. [DOI link]
Composition #14: Anjaneyulu, ASR., Rao, VL., Sreedhar, K. ent-kaurane and beyerane diterpenoids from Excoecaria agallocha. journal of natural products, 2002, vol. 65, no. 3, p. 382–385. DOI: 10.1021/np010262u. [DOI link]
Composition #15: Anjaneyulu, ASR., Rao, VL., Sreedhar, K. ent-kaurane and beyerane diterpenoids from Excoecaria agallocha. journal of natural products, 2002, vol. 65, no. 3, p. 382–385. DOI: 10.1021/np010262u. [DOI link]
Composition #16: Anjaneyulu, ASR., Rao, VL., Sreedhar, K. ent-kaurane and beyerane diterpenoids from Excoecaria agallocha. journal of natural products, 2002, vol. 65, no. 3, p. 382–385. DOI: 10.1021/np010262u. [DOI link]
Composition #17: Konishi, T., Yamazoe, K., Kanzato, M., Konoshima, T., Fujiwara, Y. Three diterpenoids (Excoecarins V1-V3) and a flavanone glycoside from the fresh stem of Excoecaria agallocha . chemical & pharmaceutical bulletin, 2003, vol. 51, no. 10, p. 1142–1146. DOI: 10.1248/cpb.51.1142. [DOI link]
Composition #18: Konishi, T., Yamazoe, K., Konoshima, T., Fujiwara, Y. Seco-labdane type diterpenes from Excoecaria agallocha. phytochemistry, 2003, vol. 64, no. 4, p. 835–840. DOI: 10.1016/j.phytochem.2003.09.001. [DOI link]
Composition #19: Konishi, T., Yamazoe, K., Konoshima, T., Fujiwara, Y. Seco-labdane type diterpenes from Excoecaria agallocha. phytochemistry, 2003, vol. 64, no. 4, p. 835–840. DOI: 10.1016/j.phytochem.2003.09.001. [DOI link]
Composition #20: ERICKSON, KL., BEUTLER, JA., CARDELLINA, JH., MCMAHON, JB., NEWMAN, DJ., BOYD, MR. A NOVEL PHORBOL ESTER FROM EXCOECARIA-AGALLOCHA. journal of natural products-lloydia, 1995, vol. 58, no. 5, p. 769–772. DOI: 10.1021/np50119a020. [DOI link]
Composition #21: Konishi, T., Kiyosawa, S., Konoshima, T., Fujiwara, Y. Chemical structures of excoecarins A, B and C: Three new labdane-type diterpenes from wood, Excoecaria agallocha . chemical & pharmaceutical bulletin, 1996, vol. 44, no. 11, p. 2100–2102. .