EFSA
ecomole
vscht
  2. Epazote (as plant) // Chenopodium ambrosioides L. // Dysphania ambrosioides (L.) Mosyakin & Clemants // Dysphania anthelmintica (L.) Mosyakin & Clemants

Epazote (as plant) // Chenopodium ambrosioides L. // Dysphania ambrosioides (L.) Mosyakin & Clemants // Dysphania anthelmintica (L.) Mosyakin & Clemants

Family:
Amaranthaceae
Approval state:
Approved
Number of articles retrieved:
1059
Number of processed references:
8
Compositions
#1: Camphor (herb) #2: Pinocarvone (herb) #3: cis-ascaridol (herb) #4: trans-ascaridol (herb) #5: Alkaloids (unspecified) #6: Saponins (unspecified) #7: Tannins (unspecified) #8: Cardiac glycosides (unspecified) #9: Phlobotannins (unspecified) #10: Ascaridol in essential oil #11: Ascaridol (essential oil from leaves) #12: Ascaridol (leaves)
Endpoint Studies
#1: Cases of hepatotoxicity with a.o. Increased levels of ASAT and ALAT and gamma-glutamyl transferase, #2: Mild cytoplasmic vacuolation of hepatocytes, mild hepatic congestion in the medullar region of the kidneys after administration of water extract of fresh leaves.
Genotoxicity
#1: Increase in the percentage of cells with chromosome aberration and in the frequency of sister chromatid exchange when lymphocyte cultures were exposed to infusion or decoction of the aerial parts.
Composition #1: Omidbaigi, R., Sefidkon, F., Nasrabadi, F.B. Essential oil content and compositions of chenopodium ambrosioides l. journal of essential oil-bearing plants, 2005, vol. 8, no. 2, p. 154–158. DOI: 10.1080/0972060X.2005.10643436. [DOI link]
Composition #2: Omidbaigi, R., Sefidkon, F., Nasrabadi, F.B. Essential oil content and compositions of chenopodium ambrosioides l. journal of essential oil-bearing plants, 2005, vol. 8, no. 2, p. 154–158. DOI: 10.1080/0972060X.2005.10643436. [DOI link]
Composition #3: Omidbaigi, R., Sefidkon, F., Nasrabadi, F.B. Essential oil content and compositions of chenopodium ambrosioides l. journal of essential oil-bearing plants, 2005, vol. 8, no. 2, p. 154–158. DOI: 10.1080/0972060X.2005.10643436. [DOI link]
Composition #4: Omidbaigi, R., Sefidkon, F., Nasrabadi, F.B. Essential oil content and compositions of chenopodium ambrosioides l. journal of essential oil-bearing plants, 2005, vol. 8, no. 2, p. 154–158. DOI: 10.1080/0972060X.2005.10643436. [DOI link]
Composition #5: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #6: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #7: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #8: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #9: Khan, Amir Muhammad., Qureshi, Rizwana Aleem., Ullah, Faizan., Gilani, Syed Aneel., Nosheen, Asia., Sahreen, Sumaira., Laghari, Muhammad Khan., Laghari, Muhammad Yousif., Shafiq-Ur-Rehman., Hussain, Ishtiaq., Murad, Waheed. Phytochemical analysis of selected medicinal plants of Margalla Hills and surroundings . journal of medicinal plants research, 2011, vol. 5, no. 25, p. 6017–6023. DOI: 10.5897/JMPR11.869. [DOI link]
Composition #10: Blanckaert, Isabelle., Paredes-Flores, Martin., Espinosa-Garcia, Francisco J., Pinero, Daniel., Lira, Rafael. Ethnobotanical, morphological, phytochemical and molecular evidence for the incipient domestication of Epazote (Chenopodium ambrosioides L.: Chenopodiaceae) in a semi-arid region of Mexico . genetic resources and crop evolution, 2012, vol. 59, no. 4, p. 557–573. DOI: 10.1007/s10722-011-9704-7. [DOI link]
Composition #11: Pereira Paes, Joao Paulo., Rondelli, Vando Miossi., Costa, Adilson Vidal., Vianna, Ulysses Rodrigues., De Queiroz, Vagner Tebaldi. CHEMICAL CHARACTERIZATION AND EFFECT OF ESSENTIAL OIL FROM MEXICAN-TEA ON TWOSPOTTED SPIDER MITE . revista brasileira de fruticultura, 2015, vol. 37, no. 2, p. 346–354. DOI: 10.1590/0100-2945-057/14. [DOI link]
Composition #12: Degenhardt, Ruth T., Farias, Ingrid V., Grassi, Liliane T., Franchi, Gilberto C., Jr., Nowill, Alexandre E., Bittencourt, Christiane M. da S., Wagner, Theodoro M., de Souza, Marcia M., Cruz, Alexandre Bella., Malheiros, Angela. Characterization and evaluation of the cytotoxic potential of the essential oil of Chenopodium ambrosioides . revista brasileira de farmacognosia-brazilian journal of pharmacognosy, 2016, vol. 26, no. 1, p. 56–61. DOI: 10.1016/j.bjp.2015.08.012. [DOI link]
Endpoint study #1: Derraji, S., Mahassin, F., Rhalem, N., Ouzzif, Z. Hepatotoxicity by Chenopodium ambrosioides about 3 comments (collected in the Hospital Military Instruction Mohammed V, Rabat - Morocco) Hépatotoxicité par Chenopodium ambrosioides à propos de 3 observations (colligées à l'hôpital militaire d'instruction Mohammed V, Rabat - Maroc) . toxicologie analytique et clinique, 2014, vol. 26, no. 3, p. 176–180. DOI: 10.1016/j.toxac.2014.05.001. [DOI link]
Endpoint study #2: da Silva, Marcel Gianni C., Amorim, Raimundo Neilson L., Camara, Carlos C., Fontenele Neto, Jose Domingues., Soto-Blanco, Benito. Acute and Sub-Chronic Toxicity of Aqueous Extracts of Chenopodium ambrosioides Leaves in Rats . journal of medicinal food, 2014, vol. 17, no. 9, p. 979–984. DOI: 10.1089/jmf.2013.0134. [DOI link]
Genotox #1: Gadano, AB., Gurni, AA., Carballo, MA. Argentine folk medicine: Genotoxic effects of Chenopodiaceae family. journal of ethnopharmacology, 2006, vol. 103, no. 2, p. 246–251. DOI: 10.1016/j.jep.2005.08.043. [DOI link]