EFSA
ecomole
vscht
  2. Duboisia leichhardtii (F.Muell.) F.Muell.

Duboisia leichhardtii (F.Muell.) F.Muell.

Family:
Solanaceae
Approval state:
Approved
Number of articles retrieved:
95
Number of processed references:
8
Compositions
#1: l-hyoscine, dl-hyoscine, norhyoscyamine in dried leaves #2: 3a,7b-dihydroxynortropane in aerial parts #3: Calystegines in aerial parts #4: Atropine in leaves #5: Scopolamine in leaves #6: Norhyoscyamine traces in leaves #7: Norscopolamine in leaves #8: littorine in leaves #9: hyoscyamine in leaves #10: scopolamine in leaves #11: scopolamine in leaves #12: Total alkaloids in leaves #13: Butropine and Valtropine in leaves #14: Scopolamine in roots #15: Scopolamine in leaves #16: Scopolamine in stem #17: Hyoscyamine in stem #18: Hyoscyamine in leaves #19: Hyoscyamine in roots #20: calystegines B1, B2 and B 4, and calystegines C1, C2
Endpoint Studies
#1: glycosidase and galactosidase inhibitory activities of calystegine B2
Genotoxicity
Composition #1: Griffin, W. J. The alkaloids of Duboisia leichhardtii. australasian journal of pharmacy, 1965, vol. 46, p. S128–S131. .
Composition #2: Asano, N., Yokoyama, K., Sakurai, M., Ikeda, K., Kizu, H., Kato, A., Arisawa, M., Hoke, D., Drager, B., Watson, AA., Nash, RJ. Dihydroxynortropane alkaloids from calystegine-producing plants. phytochemistry, 2001, vol. 57, no. 5, p. 721–726. DOI: 10.1016/S0031-9422(01)00131-5. [DOI link]
Composition #3: Asano, N., Yokoyama, K., Sakurai, M., Ikeda, K., Kizu, H., Kato, A., Arisawa, M., Hoke, D., Drager, B., Watson, AA., Nash, RJ. Dihydroxynortropane alkaloids from calystegine-producing plants. phytochemistry, 2001, vol. 57, no. 5, p. 721–726. DOI: 10.1016/S0031-9422(01)00131-5. [DOI link]
Composition #4: Kitamura, Y., Tominaga, Y., Ikenaga, T. Winter cherry bugs feed on plant tropane alkaloids and de-epoxidize scopolamine to atropine . journal of chemical ecology, 2004, vol. 30, no. 10, p. 2085–2090. DOI: 10.1023/B:JOEC.0000045597.51021.f8. [DOI link]
Composition #5: Kitamura, Y., Tominaga, Y., Ikenaga, T. Winter cherry bugs feed on plant tropane alkaloids and de-epoxidize scopolamine to atropine . journal of chemical ecology, 2004, vol. 30, no. 10, p. 2085–2090. DOI: 10.1023/B:JOEC.0000045597.51021.f8. [DOI link]
Composition #6: Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . phytochemistry, 2016, vol. 131, p. 44–56. DOI: 10.1016/j.phytochem.2016.08.008. [DOI link]
Composition #7: Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . phytochemistry, 2016, vol. 131, p. 44–56. DOI: 10.1016/j.phytochem.2016.08.008. [DOI link]
Composition #8: Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . phytochemistry, 2016, vol. 131, p. 44–56. DOI: 10.1016/j.phytochem.2016.08.008. [DOI link]
Composition #9: Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . phytochemistry, 2016, vol. 131, p. 44–56. DOI: 10.1016/j.phytochem.2016.08.008. [DOI link]
Composition #10: Ullrich, Sophie Friederike., Averesch, Nils J. H., Castellanos, Leonardo., Choi, Young Hae., Rothauer, Andreas., Kayser, Oliver. Discrimination of wild types and hybrids of Duboisia myoporoides and Duboisia leichhardtii at different growth stages using H-1 NMR-based metabolite profiling and tropane alkaloids-targeted HPLC-MS analysis . phytochemistry, 2016, vol. 131, p. 44–56. DOI: 10.1016/j.phytochem.2016.08.008. [DOI link]
Composition #11: Ullrich, Sophie Friederike., Rothauer, Andreas., Hagels, Hansjoerg., Kayser, Oliver. Influence of Light, Temperature, and Macronutrients on Growth and Scopolamine Biosynthesis in Duboisia species . planta medica, 2017, vol. 83, no. 11, p. 937–945. DOI: 10.1055/s-0043-106435. [DOI link]
Composition #12: ROSENBLUM, EI., TAYLOR, WS. THE ALKALOIDS OF DUBOISIA LEICHHARDTII - BUTROPINE AND VALTROPINE. journal of pharmacy and pharmacology, 1954, vol. 6, no. 6, p. 410–415. .
Composition #13: ROSENBLUM, EI., TAYLOR, WS. THE ALKALOIDS OF DUBOISIA LEICHHARDTII - BUTROPINE AND VALTROPINE. journal of pharmacy and pharmacology, 1954, vol. 6, no. 6, p. 410–415. .
Composition #14: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #15: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #16: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #17: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #18: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #19: KITAMURA, Y., SATO, M., MIURA, H. DIFFERENCES OF ATROPINE ESTERASE-ACTIVITY BETWEEN INTACT ROOTS AND CULTURED ROOTS OF VARIOUS TROPANE ALKALOID-PRODUCING PLANTS . phytochemistry, 1992, vol. 31, no. 4, p. 1191–1194. DOI: 10.1016/0031-9422(92)80258-G. [DOI link]
Composition #20: Kato, A., Asano, N., Kizu, H., Matsui, K., Suzuki, S., Arisawa, M. Calystegine alkaloids from Duboisia leichhardtii. phytochemistry, 1997, vol. 45, no. 2, p. 425–429. DOI: 10.1016/S0031-9422(96)00865-5. [DOI link]
Endpoint study #1: Kato, A., Asano, N., Kizu, H., Matsui, K., Suzuki, S., Arisawa, M. Calystegine alkaloids from Duboisia leichhardtii. phytochemistry, 1997, vol. 45, no. 2, p. 425–429. DOI: 10.1016/S0031-9422(96)00865-5. [DOI link]