EFSA Compendium of Botanicals

Draft - work in progress

Dryopteris marginalis (L.) A.Gray

Family:: Dryopteridaceae
Approval state:: Approved
Number of articles retrieved:: 31
Number of processed references:: 3

Compositions

#1: margaspidin in rhizomes #2: Filicin in rhizomes #3: phloroglucinol derivatives in rhizomes #4: Margaspidin in rhizomes #5: phloroglucinol derivatives in the plant

Endpoint Studies

Genotoxicity

Composition #1: Penttilä, A., Kapadia, G.J. Isolation, structure, and synthesis of margaspidin, a new dryopteris phloroglucinol derivative. journal of pharmaceutical sciences, 1965, vol. 54, no. 9, p. 1362–1364. DOI: 10.1002/jps.2600540928. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ether
Substance:

margaspidin (RF-00003481-PAR)
Analytical method code:

Gaschromatography (GC) (F037A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

margaspidin in rhizomes

Composition #2: WIDEN, CJ., BRITTON, DM. CHROMATOGRAPHIC AND CYTOLOGICAL STUDY OF DRYOPTERIS-FILIX-MAS AND RELATED TAXA IN NORTH-AMERICA . canadian journal of botany, 1971, vol. 49, no. 9, p. 1589–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ether
Substance:

phloroglucinol derivatives (RF-00004380-PAR)
Additional substance description:

filicin
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.95-2.58
Internal remarks:

Filicin in rhizomes

Composition #3: WIDEN, CJ., BRITTON, DM. CHROMATOGRAPHIC AND CYTOLOGICAL STUDY OF DRYOPTERIS-FILIX-MAS AND RELATED TAXA IN NORTH-AMERICA . canadian journal of botany, 1971, vol. 49, no. 9, p. 1589–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ether
Substance:

phloroglucinol derivatives (RF-00004380-PAR)
Additional substance description:

alb-aspidin (traces), para-aspidin, methylen-bis-aspidinol, des-aspidin, phloraspidinol, methylene-bis-des-aspidinol, floraspin, flavaspidic acid
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

phloroglucinol derivatives in rhizomes

Composition #4: WIDEN, CJ., BRITTON, DM. CHROMATOGRAPHIC AND CYTOLOGICAL STUDY OF DRYOPTERIS-FILIX-MAS AND RELATED TAXA IN NORTH-AMERICA . canadian journal of botany, 1971, vol. 49, no. 9, p. 1589–&. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ether
Substance:

margaspidin (RF-00003481-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Margaspidin in rhizomes

Composition #5: LOUNASMA.M., WIDEN, CJ., REICHSTE.T. MASS-SPECTRA OF NEW PHLOROGLUCIDES, ESPECIALLY THOSE WITH VALERYL SIDE CHAINS . helvetica chimica acta, 1973, vol. 56, no. 3, p. 1133–1144. DOI: 10.1002/hlca.19730560337. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Substance:

phloroglucinol derivatives (RF-00004380-PAR)
Additional substance description:

valeryl derivatives of phloroglucinol
Analytical method code:

LC-MS (F026A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

phloroglucinol derivatives in the plant