EFSA Compendium of Botanicals

Draft - work in progress

Dryobalanops sumatrensis (J.F.Gmel.) Kosterm. // Dryobalanops aromatica C.F.Gaertn.

Family:: Dipterocarpaceae
Approval state:: Approved
Number of articles retrieved:: 208
Number of processed references:: 5

Compositions

#1: hederagenin in resin #2: Condensed tannins in seeds #3: laevifonol, ampelopsin E, α-viniferin, ε-viniferin, diptoindonesin A in stem bark #4: bergenin in stem bark #5: gamma-viniferin in stem bulk #6: laevifonol in stem bulk #7: malaysianol A in stem bulk #8: flexuasol A in stem bulk #9: ampelopsin in stem bulk #10: ε-viniferin in stem bulk #11: vaticanol B in stem bulk #12: vaticanol C in stem bulk #13: diptoindonesin A in stem bulk #14: bergenin in stem bulk #15: camphor in unspecified part

Endpoint Studies

Genotoxicity

Composition #1: Carrick, John., Chan, K. C., Cheung, H. T. Phytochemical survey of Malaya - chemical screening. chemical & pharmaceutical bulletin, 1968, vol. 16, no. 12, p. 2436–41. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

(resine)
Substance:

hederagenin (RF-00004435-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hederagenin in resin

Composition #2: Nakagawa, M., Nakashizuka, T. Relationships between physical and chemical characteristics of dipterocarp seeds . seed science research, 2004, vol. 14, no. 4, p. 363–369. DOI: 10.1079/SSR2004181. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol / ethanol
Substance:

Proanthocyanidins (condensed tannins) Proanthocyanidins (condensed tannins) (RF-00004370-PAR)
Analytical method code:

Phytochemical screening (F604A)
Analytical method - additional description:

Folin–Ciocalteu and proanthocyanidin methods
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.1
Internal remarks:

Condensed tannins in seeds

Composition #3: Wibowo, A., Ahmat, N., Hamzah, A. S., Sufian, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M., Takayama, H. Malaysianol A, a new trimer resveratrol oligomer from the stem bark of Dryobalanops aromatica . fitoterapia, 2011, vol. 82, no. 4, p. 676–681. DOI: 10.1016/j.fitote.2011.02.006. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone / MeOH-diethyl ether
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

laevifonol, ampelopsin E, α-viniferin, ε-viniferin, diptoindonesin A
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

laevifonol, ampelopsin E, α-viniferin, ε-viniferin, diptoindonesin A in stem bark

Composition #4: Wibowo, A., Ahmat, N., Hamzah, A. S., Sufian, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M., Takayama, H. Malaysianol A, a new trimer resveratrol oligomer from the stem bark of Dryobalanops aromatica . fitoterapia, 2011, vol. 82, no. 4, p. 676–681. DOI: 10.1016/j.fitote.2011.02.006. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone / MeOH-diethyl ether
Substance:

Bergenin (RF-00010986-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

bergenin in stem bark

Composition #5: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

gamma-viniferin
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.50
Internal remarks:

gamma-viniferin in stem bulk

Composition #6: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

laevifonol
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.55
Internal remarks:

laevifonol in stem bulk

Composition #7: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

malaysianol A
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.78
Internal remarks:

malaysianol A in stem bulk

Composition #8: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

flexuasol A
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.66
Internal remarks:

flexuasol A in stem bulk

Composition #9: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

ampelopsin
Analytical method code:

Chromatographic tests (F015A)
Analytical method - additional description:

vacuum liquid chromatography (VLC)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.63
Internal remarks:

ampelopsin in stem bulk

Composition #10: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

ε-viniferin
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.33
Internal remarks:

ε-viniferin in stem bulk

Composition #11: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

vaticanol B
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.25
Internal remarks:

vaticanol B in stem bulk

Composition #12: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

vaticanol C
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.25
Internal remarks:

vaticanol C in stem bulk

Composition #13: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Stilbenes, stilbene derivatives (RF-00000284-VET)
Additional substance description:

diptoindonesin A
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.5
Internal remarks:

diptoindonesin A in stem bulk

Composition #14: Wibowo, A., Ahmat, N., Hamzah, A. S., Ismail, N. H., Ahmad, R., Jaafar, F. M. Resveratrol oligomers from the stem bark of Dryobalanops aromatica. biochemical systematics and ecology, 2012, vol. 40, p. 62–64. DOI: 10.1016/j.bse.2011.09.013. [DOI link]

Language:

English (en)
Plant part:

Stem / stalk (as part-nature) (A067S)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane/EtOAc and EtOAc/MeOH (dired powder)
Substance:

Bergenin (RF-00010986-PAR)
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.66
Internal remarks:

bergenin in stem bulk

Composition #15: Le, Tian-Xin., Ho, Anthony Siong-Hock., Mah, Siau-Hui., Wong, Tin-Wui., Ong, Hean-Chooi., Loh, Patrick Heng-Meng., Lim, Yang-Mooi. Chemical composition of essential oil of exudates of Dryobalanops aromatica . tropical journal of pharmaceutical research, 2017, vol. 16, no. 3, p. 621–625. DOI: 10.4314/tjpr.v16i3.17. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(-)-camphor (RF-00003469-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.99 - 1.14
Internal remarks:

camphor in unspecified part