EFSA
ecomole
vscht
  2. Longan (as plant) // Dimocarpus longan Lour. // Euphoria longana Lam.

Longan (as plant) // Dimocarpus longan Lour. // Euphoria longana Lam.

Family:
Sapindaceae
Approval state:
Approved
Number of articles retrieved:
1551
Number of processed references:
6
Compositions
#1: acetonylgeraniin A, acetonylgeraniin B, gallic acid, corilagin, and chebulagic acid in seed #2: Xanthumin in fruits #3: Naphthalene in seeds #4: Gitoxigenin in fruits #5: corilagin in fruits #6: gallic acid in seed #7: gallic acid in stem #8: corilagin in seed extract #9: gallic acid in seed extract #10: gallic acid in Fruit
Endpoint Studies
#1: oral LD50 is higher than 5000 mg/kg in both male and female mice. Following OECD guideline. Consequently, the NOAEL (no-observed-adverse-effect-level) of LSE was fixed at 5000 mg/kg #2: Hematology analysis revealed that % eosinophil in male rats was significantly increased at the dose of 400 mg/kg of LSE (P < 0.05) while other hematological parameters were not changed after 4 weeks of treatment #3: alfa amylase inhibitor activity #4: α-Glucosidase inhibitor activity #5: b-Glucosidase inhibitor activity
Genotoxicity
Composition #1: Hsu, Feng Lin., Chyn, Ling. Studies on the tannins from Euphoria longana LAM. proceedings of the national science council, republic of china, part a: physical science and engineering, 1991, vol. 15, no. 6, p. 541–6. .
Composition #2: Chen, F.X., Wu, S.H., Zheng, S.X., Sheng, S.L., Li, Y.Y., Wen, F.Y., Li, X.L. The preliminary determination of volatile constituents of longan arillus, epicarpium and seeds by gas chromatography-mass spectrometry coupled with solid-phase microextraction. acta horticulturae, 2010, vol. 863, p. 653–658. .
Composition #3: Chen, F.X., Wu, S.H., Zheng, S.X., Sheng, S.L., Li, Y.Y., Wen, F.Y., Li, X.L. The preliminary determination of volatile constituents of longan arillus, epicarpium and seeds by gas chromatography-mass spectrometry coupled with solid-phase microextraction. acta horticulturae, 2010, vol. 863, p. 653–658. .
Composition #4: Chen, F.X., Wu, S.H., Zheng, S.X., Sheng, S.L., Li, Y.Y., Wen, F.Y., Li, X.L. The preliminary determination of volatile constituents of longan arillus, epicarpium and seeds by gas chromatography-mass spectrometry coupled with solid-phase microextraction. acta horticulturae, 2010, vol. 863, p. 653–658. .
Composition #5: Rangkadilok, N., Worasuttayangkurn, L., Bennett, RN., Satayavivad, J. Identification and quantification of polyphenolic compounds in longan (Euphoria longana Lam.) fruit . journal of agricultural and food chemistry, 2005, vol. 53, no. 5, p. 1387–1392. DOI: 10.1021/jf0403484. [DOI link]
Composition #6: Rangkadilok, N., Worasuttayangkurn, L., Bennett, RN., Satayavivad, J. Identification and quantification of polyphenolic compounds in longan (Euphoria longana Lam.) fruit . journal of agricultural and food chemistry, 2005, vol. 53, no. 5, p. 1387–1392. DOI: 10.1021/jf0403484. [DOI link]
Composition #7: Wang, Bor-Sen., Tang, Chi-Hua., Chiu, Chih-Kwang., Huang, Ming-Hsing. Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production . food chemistry, 2012, vol. 135, no. 2, p. 440–445. DOI: 10.1016/j.foodchem.2012.04.125. [DOI link]
Composition #8: Worasuttayangkurn, Luksamee., Watcharasit, Piyajit., Rangkadilok, Nuchanart., Suntararuks, Sumitra., Khamkong, Pattaya., Satayavivad, Jutamaad. Safety evaluation of longan seed extract: Acute and repeated oral administration . food and chemical toxicology, 2012, vol. 50, no. 11, p. 3949–3955. DOI: 10.1016/j.fct.2012.07.068. [DOI link]
Composition #9: Worasuttayangkurn, Luksamee., Watcharasit, Piyajit., Rangkadilok, Nuchanart., Suntararuks, Sumitra., Khamkong, Pattaya., Satayavivad, Jutamaad. Safety evaluation of longan seed extract: Acute and repeated oral administration . food and chemical toxicology, 2012, vol. 50, no. 11, p. 3949–3955. DOI: 10.1016/j.fct.2012.07.068. [DOI link]
Composition #10: Li, Po-Hsien., Lin, Yu-Wen., Lu, Wen-Chien., Hu, Jyh-Ming., Huang, Da-Wei. In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against alpha-Glucosidase and beta-Galactosidase . international journal of food properties, 2016, vol. 19, no. 8, p. 1786–1797. DOI: 10.1080/10942912.2015.1085398. [DOI link]
Endpoint study #1: Worasuttayangkurn, Luksamee., Watcharasit, Piyajit., Rangkadilok, Nuchanart., Suntararuks, Sumitra., Khamkong, Pattaya., Satayavivad, Jutamaad. Safety evaluation of longan seed extract: Acute and repeated oral administration . food and chemical toxicology, 2012, vol. 50, no. 11, p. 3949–3955. DOI: 10.1016/j.fct.2012.07.068. [DOI link]
Endpoint study #2: Worasuttayangkurn, Luksamee., Watcharasit, Piyajit., Rangkadilok, Nuchanart., Suntararuks, Sumitra., Khamkong, Pattaya., Satayavivad, Jutamaad. Safety evaluation of longan seed extract: Acute and repeated oral administration . food and chemical toxicology, 2012, vol. 50, no. 11, p. 3949–3955. DOI: 10.1016/j.fct.2012.07.068. [DOI link]
Endpoint study #3: Li, Po-Hsien., Lin, Yu-Wen., Lu, Wen-Chien., Hu, Jyh-Ming., Huang, Da-Wei. In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against alpha-Glucosidase and beta-Galactosidase . international journal of food properties, 2016, vol. 19, no. 8, p. 1786–1797. DOI: 10.1080/10942912.2015.1085398. [DOI link]
Endpoint study #4: Li, Po-Hsien., Lin, Yu-Wen., Lu, Wen-Chien., Hu, Jyh-Ming., Huang, Da-Wei. In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against alpha-Glucosidase and beta-Galactosidase . international journal of food properties, 2016, vol. 19, no. 8, p. 1786–1797. DOI: 10.1080/10942912.2015.1085398. [DOI link]
Endpoint study #5: Li, Po-Hsien., Lin, Yu-Wen., Lu, Wen-Chien., Hu, Jyh-Ming., Huang, Da-Wei. In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against alpha-Glucosidase and beta-Galactosidase . international journal of food properties, 2016, vol. 19, no. 8, p. 1786–1797. DOI: 10.1080/10942912.2015.1085398. [DOI link]