EFSA Compendium of Botanicals

Draft - work in progress

Digitalis lanata Ehrh.

Family:: Plantaginaceae
Approval state:: Approved
Number of articles retrieved:: 1188
Number of processed references:: 1

Compositions

#1: digitoxin in leaves #2: Lanatoside A in leaves #3: Lanatoside B in leaves #4: total cardenolides in leaves #5: Lanatoside C+digoxin in leaves

Endpoint Studies

Genotoxicity

Composition #1: Braga, FC., Kreis, W., Recio, RA., deOliveira, AB. Quantitative evaluation of cardenolides in a Brazilian Digitalis lanata cultivar and perspectives of its industrial use . quimica nova, 1997, vol. 20, no. 5, p. 481–485. DOI: 10.1590/S0100-40421997000500008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 70% (20,0 mL), at 80°C, 10 min
Substance:

digitoxin (RF-00003778-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.02
Internal remarks:

digitoxin in leaves

Composition #2: Braga, FC., Kreis, W., Recio, RA., deOliveira, AB. Quantitative evaluation of cardenolides in a Brazilian Digitalis lanata cultivar and perspectives of its industrial use . quimica nova, 1997, vol. 20, no. 5, p. 481–485. DOI: 10.1590/S0100-40421997000500008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 70% (20,0 mL), at 80°C, 10 min
Substance:

lanatoside A (RF-00003894-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.08
Internal remarks:

Lanatoside A in leaves

Composition #3: Braga, FC., Kreis, W., Recio, RA., deOliveira, AB. Quantitative evaluation of cardenolides in a Brazilian Digitalis lanata cultivar and perspectives of its industrial use . quimica nova, 1997, vol. 20, no. 5, p. 481–485. DOI: 10.1590/S0100-40421997000500008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 70% (20,0 mL), at 80°C, 10 min
Substance:

lanatoside B (RF-00003895-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.29
Internal remarks:

Lanatoside B in leaves

Composition #4: Braga, FC., Kreis, W., Recio, RA., deOliveira, AB. Quantitative evaluation of cardenolides in a Brazilian Digitalis lanata cultivar and perspectives of its industrial use . quimica nova, 1997, vol. 20, no. 5, p. 481–485. DOI: 10.1590/S0100-40421997000500008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 70% (20,0 mL), at 80°C, 10 min
Substance:

cardenolide glycosides cardenolide glycosides (RF-00004348-PAR)
Additional substance description:

Total cardenolides
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.45
Internal remarks:

total cardenolides in leaves

Composition #5: Braga, FC., Kreis, W., Recio, RA., deOliveira, AB. Quantitative evaluation of cardenolides in a Brazilian Digitalis lanata cultivar and perspectives of its industrial use . quimica nova, 1997, vol. 20, no. 5, p. 481–485. DOI: 10.1590/S0100-40421997000500008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH 70% (20,0 mL), at 80°C, 10 min
Substance:

digoxin (RF-00003779-PAR)
Additional substance description:

Lanatoside C + digoxin
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Millimole/kilogram (G070A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.82
Internal remarks:

Lanatoside C+digoxin in leaves