Draft - work in progress
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- Descurainia sophia (L.) Webb ex Prantl
Descurainia sophia (L.) Webb ex Prantl
- Family:
- Brassicaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 613
- Number of processed references:
- 4
Composition #1: Li, Jing., Liu, Xingang., Dong, Fengshou., Xu, Jun., Zheng, Yongquan., Shan, Weili. Determination of the Volatile Composition in Essential Oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by Gas Chromatography/Mass Spectrometry (GC/MS) . molecules, 2010, vol. 15, no. 1, p. 233–240. DOI: 10.3390/molecules15010233.
[
DOI link]
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Plant part:
Flowering top (as part-nature) (A166H)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
Hydrodistillation
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Substance:
alpha-cedrol (RF-00003645-PAR)
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Additional substance description:
cedrol
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.43
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Internal remarks:
cedrol (flowering aerial part)
Composition #2: Li, Jing., Liu, Xingang., Dong, Fengshou., Xu, Jun., Zheng, Yongquan., Shan, Weili. Determination of the Volatile Composition in Essential Oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by Gas Chromatography/Mass Spectrometry (GC/MS) . molecules, 2010, vol. 15, no. 1, p. 233–240. DOI: 10.3390/molecules15010233.
[
DOI link]
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Plant part:
Flowering top (as part-nature) (A166H)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
Hydrodistillation
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Substance:
1,8-cineole (RF-00003470-PAR)
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
2.58
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Internal remarks:
1,8-cineole (flowering aerial part)
Composition #3: Li, Jing., Liu, Xingang., Dong, Fengshou., Xu, Jun., Zheng, Yongquan., Shan, Weili. Determination of the Volatile Composition in Essential Oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by Gas Chromatography/Mass Spectrometry (GC/MS) . molecules, 2010, vol. 15, no. 1, p. 233–240. DOI: 10.3390/molecules15010233.
[
DOI link]
-
-
Plant part:
Flowering top (as part-nature) (A166H)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
Hydrodistillation
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Substance:
tagetone (RF-00003596-PAR)
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Additional substance description:
trans-tagetone
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1.04
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Internal remarks:
trans-tagetone (flowering aerial part)
Composition #4: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
psoralen (RF-00004015-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Psoralen (aerial part)
Composition #5: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
Bergapten (RF-00003837-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Bergapten (aerial part)
Composition #6: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
Methoxsalen Methoxsalen (RF-00003863-PAR)
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Additional substance description:
Xanthotoxin
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Xanthotoxin (aerial part)
Composition #7: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
Scopolin (RF-00010995-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Scopolin (aerial part)
Composition #8: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
Isoscopoletin (RF-00010985-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Isoscopoletin (aerial part)
Composition #9: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
Xanthotoxol (RF-00011114-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Xanthotoxol (aerial part)
Composition #10: Mohamed, Nawal H., Mahrous, Atta E. Chemical Constituents of Descurainia sophia L. and its Biological Activity . records of natural products, 2009, vol. 3, no. 1, p. 58–67. .
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Methanol, ethyl acetate
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Substance:
scopoletin (RF-00004048-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Scopoletin (aerial part)
Composition #11: Khodarahmi, E., Asghari, G. H., Hassanzadeh, F., Mirian, M., Khodarahmi, G. A. Cytotoxic evaluation of volatile oil from Descurainia sophia seeds on MCF-7 and HeLa cell lines . research in pharmaceutical sciences, 2015, vol. 10, no. 2, p. 169–176. .
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
distillation
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Substance:
Isothiocyanates (RF-00010827-PAR)
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Additional substance description:
3-butenyl isothiocyanate
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Analytical method code:
GC-MS (F046A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
3-butenyl isothiocyanate (seeds)
Endpoint study
#1: Zarei, Mohammad., Poursharifi, Mina. Searching for alpha-glucosidase inhibitory activity in hexane extracts by some plants from Kurdistan province. international journal of advanced biological and biomedical research, 2015, vol. 3, no. 3, p. 291–296. .
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Study relevance:
Human health
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Plant part:
Unspecified (A07XD)
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Additional plant/substance description:
unspecified
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Type of toxicological test:
in vitro (CHD061TT)
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Route of exposure:
OTHER (OECD0PL)
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Endpoint measured:
Half maximal inhibitory concentration (CHD021EP)
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Concentration unit:
Microgram/millilitre (G052A)
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Effect concentration:
0.9
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
Descurania Sophia exhibited significant alpha glucosidase inhibitory activity with IC50 values of 0.9 μg/mL
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Effect or parameter linked to the endpoint:
enzyme inhibition (CHD032BE)
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Internal remarks:
Descurania Sophia exhibited significant alpha glucosidase inhibitory activity with IC50 values of 0.9 μg/mL