EFSA
ecomole
vscht
  2. Datura metel L. // Datura alba F.Muell. // Datura alba Rumph. ex Nees

Datura metel L. // Datura alba F.Muell. // Datura alba Rumph. ex Nees

Family:
Solanaceae
Approval state:
Approved
Number of articles retrieved:
1391
Number of processed references:
15
Compositions
#1: Hyoscyamine #2: Tropane alkaloids (root) #3: Scopolamine (Flower nectar) #4: Atropine (Flower nectar) #5: Hyoscyamine (seed) #6: Total alkaloids (seeds) #7: scopolamine (seed) #8: Hyoscine (seeds) #9: Atropine (seeds) #10: Anthraquinones #11: Cardiac gylcosides #12: Tannins #13: Saponins #14: Tannins (seed) #15: alkaloids (seeds) #16: steroidal glycosides (seed) #17: Hyoscyamine #18: Total alkaloids #19: Scopolamine #20: Alkaloids (leaves) #21: Scopolamine (leaves) #22: Atropine (leaves) #23: Atropine (fruit, flower and seed) #24: Atropine (stem) #25: Scopolamine (fruit, flower and seed) #26: Scopolamine (stem)
Endpoint Studies
#1: mortality and strong piscicidal activity to fish #2: Fresh root paste decoction is used as an abortifacient by ethnic people in North-East India #3: Contraceptive, abortive, teratogenic, neurodegenerative effects, and change in body weight in rats following oral administration of ethanolic extract of leaves #4: Musclo-sceletal, cardiovascular and haematological symptoms of poisoning after consumption of brewed plant extract #5: Plant extract induced neurotoxicity, hepatotoxicity and behaviour changes in mice.
Genotoxicity
Composition #1: Wahid, M. A., Samiullah. Standardization of active principles of indigenous pharmacopoeial drugs found in West Pakistan. pakistan journal of scientific and industrial research, 1960, vol. 3, p. 228–30. .
Composition #2: Anwar, K., Ghani, A. Alkaloids of the roots of Datura metel var fastuosa grown in Bangladesh. bangladesh pharmaceutical journal, 1973, vol. 2, no. 2, p. 25–7. .
Composition #3: Boros, Borbala., Farkas, Agnes., Jakabova, Silvia., Bacskay, Ivett., Kilar, Ferenc., Felinger, Attila. LC-MS Quantitative Determination of Atropine and Scopolamine in the Floral Nectar of Datura Species. chromatographia, 2010, vol. 71(Suppl.), p. S43–S49. .
Composition #4: Boros, Borbala., Farkas, Agnes., Jakabova, Silvia., Bacskay, Ivett., Kilar, Ferenc., Felinger, Attila. LC-MS Quantitative Determination of Atropine and Scopolamine in the Floral Nectar of Datura Species. chromatographia, 2010, vol. 71(Suppl.), p. S43–S49. .
Composition #5: Patel, Yogesh., Bhat, Savitha D., Acharya, Rabinarayan., Ashok, B. K., Shukla, V. J. Role of Shodhana on analytical parameters of Datura innoxia Mill and Datura metel Linn seeds. international journal of research in ayurveda & pharmacy, 2010, vol. 1, no. 2, p. 249–254. .
Composition #6: Patel, Yogesh., Bhat, Savitha D., Acharya, Rabinarayan., Ashok, B. K., Shukla, V. J. Role of Shodhana on analytical parameters of Datura innoxia Mill and Datura metel Linn seeds. international journal of research in ayurveda & pharmacy, 2010, vol. 1, no. 2, p. 249–254. .
Composition #7: Patel, Yogesh., Bhat, Savitha D., Acharya, Rabinarayan., Ashok, B. K., Shukla, V. J. Role of Shodhana on analytical parameters of Datura innoxia Mill and Datura metel Linn seeds. international journal of research in ayurveda & pharmacy, 2010, vol. 1, no. 2, p. 249–254. .
Composition #8: Chhatre, Vibhavari., Nesari, Tanuja., Somani, Gauresh., Chaudhari, Rahul., Sathaye, Sadhana. Studies on the process of detoxification and safety evaluation of shodhit and ashodhit Datura metel seeds for the use in Ayurvedic preparations. international journal of research in pharmaceutical sciences (madurai, india), 2012, vol. 3, no. 4), 670-67, p. 8 pp. .
Composition #9: Chhatre, Vibhavari., Nesari, Tanuja., Somani, Gauresh., Chaudhari, Rahul., Sathaye, Sadhana. Studies on the process of detoxification and safety evaluation of shodhit and ashodhit Datura metel seeds for the use in Ayurvedic preparations. international journal of research in pharmaceutical sciences (madurai, india), 2012, vol. 3, no. 4), 670-67, p. 8 pp. .
Composition #10: Karunakar, T., Shankaraiah, A., Parvathi, D., Ugandhar, T. Investigation of the phytochemical analysis and biological activities in Datura metel. Linn. european journal of biomedical and pharmaceutical sciences, 2016, vol. 3, no. 5, p. 329–334. .
Composition #11: Karunakar, T., Shankaraiah, A., Parvathi, D., Ugandhar, T. Investigation of the phytochemical analysis and biological activities in Datura metel. Linn. european journal of biomedical and pharmaceutical sciences, 2016, vol. 3, no. 5, p. 329–334. .
Composition #12: Karunakar, T., Shankaraiah, A., Parvathi, D., Ugandhar, T. Investigation of the phytochemical analysis and biological activities in Datura metel. Linn. european journal of biomedical and pharmaceutical sciences, 2016, vol. 3, no. 5, p. 329–334. .
Composition #13: Karunakar, T., Shankaraiah, A., Parvathi, D., Ugandhar, T. Investigation of the phytochemical analysis and biological activities in Datura metel. Linn. european journal of biomedical and pharmaceutical sciences, 2016, vol. 3, no. 5, p. 329–334. .
Composition #14: Babalola, S.A., Suleiman, M.M., Hassan, A.Z., Adawa, D. Evaluation of the crude methanolic seed extract of Datura metel L. as a potential oral anaesthetic in dogs. global journal of pharmacology, 2014, vol. 8, no. 2, p. 154–159. DOI: 10.5829/idosi.gjp.2014.8.2.82281. [DOI link]
Composition #15: Babalola, S.A., Suleiman, M.M., Hassan, A.Z., Adawa, D. Evaluation of the crude methanolic seed extract of Datura metel L. as a potential oral anaesthetic in dogs. global journal of pharmacology, 2014, vol. 8, no. 2, p. 154–159. DOI: 10.5829/idosi.gjp.2014.8.2.82281. [DOI link]
Composition #16: Babalola, S.A., Suleiman, M.M., Hassan, A.Z., Adawa, D. Evaluation of the crude methanolic seed extract of Datura metel L. as a potential oral anaesthetic in dogs. global journal of pharmacology, 2014, vol. 8, no. 2, p. 154–159. DOI: 10.5829/idosi.gjp.2014.8.2.82281. [DOI link]
Composition #17: Chan, T.Y.K. Herbal medicines induced anticholinergic poisoning in Hong Kong. toxins, 2016, vol. 8, no. 3 . DOI: 10.3390/toxins8030080. [DOI link]
Composition #18: Chan, T.Y.K. Herbal medicines induced anticholinergic poisoning in Hong Kong. toxins, 2016, vol. 8, no. 3 . DOI: 10.3390/toxins8030080. [DOI link]
Composition #19: Chan, T.Y.K. Herbal medicines induced anticholinergic poisoning in Hong Kong. toxins, 2016, vol. 8, no. 3 . DOI: 10.3390/toxins8030080. [DOI link]
Composition #20: Kuganathan, Navaratnarajah., Ganeshalingam, Sashikesh. Chemical Analysis of Datura Metel Leaves and Investigation of the Acute Toxicity on Grasshoppers and Red Ants . e-journal of chemistry, 2011, vol. 8, no. 1, p. 107–112. .
Composition #21: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Composition #22: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Composition #23: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Composition #24: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Composition #25: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Composition #26: Jakabova, Silvia., Vincze, Lajos., Farkas, Agnes., Kilar, Ferenc., Boros, Borbala., Felinger, Attila. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species . journal of chromatography a, 2012, vol. 1232, p. 295–301. DOI: 10.1016/j.chroma.2012.02.036. [DOI link]
Endpoint study #1: Ashraf, M., Ayub, M., Sajjad, T., Elahi, N., Ali, I., Ahmed, Z. Replacement of rotenone by locally grown herbal extracts. international journal of agriculture and biology, 2010, vol. 12, no. 1, p. 77–80. .
Endpoint study #2: Das, B., Choudhury, M.D., Talukdar, A.D. A few traditional medicinal plants used as antifertility agents by ethnic people of Tripura, India. international journal of pharmacy and pharmaceutical sciences, 2014, vol. 6, no. 3, p. 47–53. .
Endpoint study #3: Ishola, Azeez Olakunle., Adeniyi, Philip Adeyemi. Retarded hippocampal development following prenatal exposure to ethanolic leaves extract of Datura metel in wistar rats. . nigerian medical journal : journal of the nigeria medical association, 2013, vol. 54, no. 6, p. 411–4. DOI: 10.4103/0300-1652.126299. [DOI link]
Endpoint study #4: Phua, D. H., Cham, G., Seow, E. Two instances of Chinese herbal medicine poisoning in Singapore. singapore medical journal, 2008, vol. 49, no. 5, p. E131–E133. .
Endpoint study #5: Fu, Yonghong., Si, Zhihong., Li, Pumin., Li, Minghui., Zhao, He., Jiang, Lei., Xing, Yuexiao., Hong, Wei., Ruan, Lingyu., Wang, Jun-Song. Acute psychoactive and toxic effects of D-metel on mice explained by H-1 NMR based metabolomics approach . metabolic brain disease, 2017, vol. 32, no. 4, p. 1295–1309. DOI: 10.1007/s11011-017-0038-9. [DOI link]