EFSA Compendium of Botanicals

Draft - work in progress

Curcuma phaeocaulis Valeton

Family:: Zingiberaceae
Approval state:: Approved
Number of articles retrieved:: 247
Number of processed references:: 3

Compositions

#1: Sesquiterpene alkaloids #2: Furanodienone - rhizomes #3: Curcuminoids

Endpoint Studies

Genotoxicity

Composition #1: Xia Gui-Yang., Owusu Donkor Paul., Ding Li-Qin., Qiu Feng., Xia Gui-Yang., Sun De-Juan., Ma Jiang-Hao., Liu Yue., Chen Li-Xia., Zhao Feng. (+)/(-)-Phaeocaulin A-D, four pairs of new enantiomeric germacrane-type sesquiterpenes from Curcuma phaeocaulis as natural nitric oxide inhibitors. scientific reports, 2017, vol. 7, p. 43576. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 95% used in extraction from rhizomes
Substance:

sesquiterpene alkaloids (RF-00004371-PAR)
Additional substance description:

Sesquiterpene alkaloids phaeocaulin A and B
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

Structures determined by single-crystal X-ray diffractions and quantum chemical electronic circular dichroism (ECD) method
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Sesquiterpene alkaloids

Composition #2: Zhang, J. S., Guan, J., Yang, F. Q., Liu, H. G., Cheng, X. J., Li, S. P. Qualitative and quantitative analysis of four species of Curcuma rhizomes using twice development thin layer chromatography . journal of pharmaceutical and biomedical analysis, 2008, vol. 48, no. 3, p. 1024–1028. DOI: 10.1016/j.jpba.2008.07.006. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

500mg dried rhizome powder, accurately weighed, was mixed with 5mL methanol
Substance:

Furanodienone (RF-00011184-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Analytical method - additional description:

absorbtion spectra
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.71-5.84
Internal remarks:

Furanodienone - rhizomes

Composition #3: Li, Rui., Xiang, Cheng., Ye, Min., Li, Hui-Fang., Zhang, Xing., Guo, De-An. Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species . food chemistry, 2011, vol. 126, no. 4, p. 1890–1895. DOI: 10.1016/j.foodchem.2010.12.014. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

Curcumin (RF-00000108-ADD)
Additional substance description:

3 Curcuminoids: curcumin, demethoxycurcumin and bisdemethoxycurcumin)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.030-0.098
Internal remarks:

Curcuminoids