EFSA Compendium of Botanicals

Draft - work in progress

Combretum micranthum G.Don.

Family:: Combretaceae
Approval state:: Approved
Number of articles retrieved:: 135
Number of processed references:: 3

Compositions

#1: Gallic acid in leaves #2: Tannins in leaves #3: alkaloids - leaves #4: cardiac glycosides - leaves #5: saponins - leaves #6: tannins - leaves #7: Combretine A and B alkaloid in leaves

Endpoint Studies

Genotoxicity

Composition #1: Spiegel, K. Jentzsch, P., Fuchs, L. The constituents of the leaves of Combretum micranthum. planta medica, 1962, vol. 10, p. 1–8. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Gallic acid in leaves

Composition #2: Spiegel, K. Jentzsch, P., Fuchs, L. The constituents of the leaves of Combretum micranthum. planta medica, 1962, vol. 10, p. 1–8. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

12-14
Internal remarks:

Tannins in leaves

Composition #3: Chika, Aminu., Bello, Shaibu Oricha. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats . journal of ethnopharmacology, 2010, vol. 129, no. 1, p. 34–37. DOI: 10.1016/j.jep.2010.02.008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

shade-dried tleaves grinded to powder, aqueous extract
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

evaluated by standard qualitative and quantitative methods of Trease and Evans (1989).
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids - leaves

Composition #4: Chika, Aminu., Bello, Shaibu Oricha. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats . journal of ethnopharmacology, 2010, vol. 129, no. 1, p. 34–37. DOI: 10.1016/j.jep.2010.02.008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

shade-dried tleaves grinded to powder, aqueous extract
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

evaluated by standard qualitative and quantitative methods of Trease and Evans (1989).
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cardiac glycosides - leaves

Composition #5: Chika, Aminu., Bello, Shaibu Oricha. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats . journal of ethnopharmacology, 2010, vol. 129, no. 1, p. 34–37. DOI: 10.1016/j.jep.2010.02.008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

shade-dried tleaves grinded to powder, aqueous extract
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

evaluated by standard qualitative and quantitative methods of Trease and Evans (1989).
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins - leaves

Composition #6: Chika, Aminu., Bello, Shaibu Oricha. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats . journal of ethnopharmacology, 2010, vol. 129, no. 1, p. 34–37. DOI: 10.1016/j.jep.2010.02.008. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

shade-dried tleaves grinded to powder, aqueous extract
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Unspecified (F598A)
Analytical method - additional description:

evaluated by standard qualitative and quantitative methods of Trease and Evans (1989).
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins - leaves

Composition #7: OGAN, AU. ALKALOIDS IN LEAVES OF COMBRETUM-MICRANTHUM - STUDIES ON WEST-AFRICAN MEDICINAL-PLANTS .7. . planta medica, 1972, vol. 21, no. 2, p. 210–&. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

with light petroleum (60'-80') and then with chloroform
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

Combretine A and B
Analytical method code:

IR and Raman Spectroscopy (F010A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Combretine A and B alkaloid in leaves