EFSA
ecomole
vscht
  2. Bitter cola (as plant) // Cola nitida (Vent.) Schott & Endl.

Bitter cola (as plant) // Cola nitida (Vent.) Schott & Endl.

Family:
Malvaceae
Approval state:
Approved
Number of articles retrieved:
292
Number of processed references:
8
Compositions
#1: cyanogenic glycosides in seeds #2: cardiac glycosides in seeds #3: oxalate in seeds #4: saponins in seeds #5: alkaloids in seeds #6: caffeine in seeds #7: anthraquinone in seeds #8: saponins in seeds #9: amygdalin in seeds #10: oxalates in seeds #11: alkaloids in seeds #12: phytic acid in seeds #13: saponin in seeds #14: Theobromine in seeds #15: Caffeine in seeds
Endpoint Studies
#1: Decrased body weight and increased levels of ASAT and ALAT after intake of caffeine-containing seed extract. #2: A water extract of seeds affected semen quality and caused necrosis in testes #3: mean arterial pressure increased
Genotoxicity
Composition #1: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .
Composition #2: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .
Composition #3: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .
Composition #4: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .
Composition #5: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .
Composition #6: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .
Composition #7: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .
Composition #8: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .
Composition #9: Bolarinwa, Islamiyat Folashade., Olaniyan, Sulaiman Adebisi., Olatunde, Sogo James., Ayandokun, Feyisayo Temilade., Olaifa, Ifasegun Alade. Effect of processing on amygdalin and cyanide contents of some Nigerian foods. journal of chemical and pharmaceutical research, 2016, vol. 8, no. 2, p. 106–113. .
Composition #10: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .
Composition #11: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .
Composition #12: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .
Composition #13: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .
Composition #14: Niemenak, N., Onomo, P. E., Fotso., Lieberei, R., Ndoumou, D. O. Purine alkaloids and phenolic compounds in three Cola species and Garcinia kola grown in Cameroon . south african journal of botany, 2008, vol. 74, no. 4, p. 629–638. DOI: 10.1016/j.sajb.2008.03.003. [DOI link]
Composition #15: Niemenak, N., Onomo, P. E., Fotso., Lieberei, R., Ndoumou, D. O. Purine alkaloids and phenolic compounds in three Cola species and Garcinia kola grown in Cameroon . south african journal of botany, 2008, vol. 74, no. 4, p. 629–638. DOI: 10.1016/j.sajb.2008.03.003. [DOI link]
Endpoint study #1: Salahdeen, H. M., Omoaghe, A. O., Isehunwa, G. O., Murtala, B. A., Alada, A. R. A. Gas chromatography mass spectrometry (GC-MS) analysis of ethanolic extracts of kolanut (Cola nitida) (vent) and its toxicity studies in rats. journal of medicinal plants research, 2015, vol. 9, no. 3, p. 56–70. .
Endpoint study #2: Oyedeji, K.O., Bolarinwa, A.F., Adegoke, A.O. Effect of aqueous extract of Cola nitida (Kola nut) on reproductive functionsin male albino rats. international journal of pharmaceutical sciences review and research, 2013, vol. 20, no. 2, p. 291–295. .
Endpoint study #3: Osim, E.E., Udia, P.M. Effects of consuming a kola nut (cola nitida) diet on mean arterial pressure in rats. pharmaceutical biology, 1993, vol. 31, no. 3, p. 193–197. DOI: 10.3109/13880209309082941. [DOI link]