EFSA Compendium of Botanicals

Draft - work in progress

Cola for nuts (as plant) // Cola acuminata (P.Beauv.) Schott & Endl. // Cola pseudo-acuminata Engl. // Sterculia acuminata P.Beauv.

Family:: Malvaceae
Approval state:: Approved
Number of articles retrieved:: 282
Number of processed references:: 5

Compositions

#1: cyanogenic glycoside in seeds #2: oxalate in seeds #3: saponin in seeds #4: cardiac glycoside in seeds #5: anthraquinones in seeds #6: caffeine in seeds #7: saponins in seeds #8: alkaloids in seeds #9: amygdalin in seed #10: alkaloids in seeds #11: saponins in seeds #12: oxalates in seeds #13: phytic acid in seeds #14: tannins in seeds #15: theobromine in seeds #16: caffeine in seeds

Endpoint Studies

Genotoxicity

Composition #1: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water and steam-distilled
Substance:

Cyanogenic glycosides (RF-00004375-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Analytical method - additional description:

titration against AgNO3
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

80.10
Internal remarks:

cyanogenic glycoside in seeds

Composition #2: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

HCl
Substance:

Oxalates (RF-00004308-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Analytical method - additional description:

titration with KMnO4
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.03
Internal remarks:

oxalate in seeds

Composition #3: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

13.33
Internal remarks:

saponin in seeds

Composition #4: Monago, C. C., Uwakwe, A. A. Tannin, oxalate, saponin, cyanogenic and cardiac glycosides contents of Cola nitida and Cola acuminata. global journal of pure and applied sciences, 2005, vol. 11, no. 4, p. 501–504. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

68.51
Internal remarks:

cardiac glycoside in seeds

Composition #5: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Anthraquinone (RF-0475-001-PPP)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.054-0.057
Internal remarks:

anthraquinones in seeds

Composition #6: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

caffeine (RF-00000038-NTR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.98-1.04
Internal remarks:

caffeine in seeds

Composition #7: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.36-0.39
Internal remarks:

saponins in seeds

Composition #8: Atanda, O. O., Olutayo, A., Mokwunye, F. C., Oyebanji, A. O., Adegunwa, M. O. The quality of Nigerian kola nuts. african journal of food science, 2011, vol. 5, no. 17, p. 904–909. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Traditional analytical techniques (wet chemical tests) (F003A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.26-2.31
Internal remarks:

alkaloids in seeds

Composition #9: Bolarinwa, Islamiyat Folashade., Olaniyan, Sulaiman Adebisi., Olatunde, Sogo James., Ayandokun, Feyisayo Temilade., Olaifa, Ifasegun Alade. Effect of processing on amygdalin and cyanide contents of some Nigerian foods. journal of chemical and pharmaceutical research, 2016, vol. 8, no. 2, p. 106–113. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol
Substance:

amygdalin (RF-00003680-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

44.53
Internal remarks:

amygdalin in seed

Composition #10: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Alkaloids (RF-00004360-PAR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.80
Internal remarks:

alkaloids in seeds

Composition #11: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Saponins (RF-00004333-PAR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.33
Internal remarks:

saponins in seeds

Composition #12: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Oxalates (RF-00004308-PAR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.71
Internal remarks:

oxalates in seeds

Composition #13: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

phytic acid (RF-00000363-NTR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.60
Internal remarks:

phytic acid in seeds

Composition #14: Dah-Nouvlessounon, Durand., Adjanohoun, Adolphe., Sina, Haziz., Noumavo, Pacome A., Diarrasouba, Nafan., Parkouda, Charles., Madode, Yann E., Dicko, Mamoudou H., Baba-Moussa, Lamine. Nutritional and anti-nutrient composition of three kola nuts (Cola nitida, Cola acuminata and Garcinia kola) produced in Benin. food and nutrition sciences, 2015, vol. 6, no. 15, p. 1395–1407. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Tannins (RF-00004337-PAR)
Substance used for equivalence:

tannic acid (RF-00004069-PAR)
Result unit:

Milligram-equivalent (G159A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.08
Internal remarks:

tannins in seeds

Composition #15: Niemenak, N., Onomo, P. E., Fotso., Lieberei, R., Ndoumou, D. O. Purine alkaloids and phenolic compounds in three Cola species and Garcinia kola grown in Cameroon . south african journal of botany, 2008, vol. 74, no. 4, p. 629–638. DOI: 10.1016/j.sajb.2008.03.003. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Theobromine (RF-00000334-TOX)
Analytical method code:

Unspecified (F598A)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

76-1277
Internal remarks:

theobromine in seeds

Composition #16: Niemenak, N., Onomo, P. E., Fotso., Lieberei, R., Ndoumou, D. O. Purine alkaloids and phenolic compounds in three Cola species and Garcinia kola grown in Cameroon . south african journal of botany, 2008, vol. 74, no. 4, p. 629–638. DOI: 10.1016/j.sajb.2008.03.003. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

caffeine (RF-00000038-NTR)
Analytical method code:

Unspecified (F598A)
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.3-16.138
Internal remarks:

caffeine in seeds