Draft - work in progress
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- Clerodendrum infortunatum L. // Clerodendrum viscosum Vent.
Clerodendrum infortunatum L. // Clerodendrum viscosum Vent.
- Family:
- Lamiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 173
- Number of processed references:
- 8
Compositions
#1: neo-clerodane diterpenoids in leaves (leaf juice is used as a strong anthelmintic, emetic, mild laxative and cholagogue)
#2: Saponins in the root bark
#3: Alkaloids in the root bark
#4: Tannins in the root bark
#5: Saponins are present in the water extract of leaves.
#6: Alcaloids (traces) are present in the water extract of leaves
#7: Tannins are present in the water extract of leaves..
#8: Tert-butyl-p-benzoquinone in flowers
#9: 5‑Hydroxymethylfurfural in leaves
#10: Benzofuran, 2,3‑dihydro‑Heterocyclic aromatic in leaves
#11: saponin in leaves
#12: tannin in leaves
#13: quinones in aqueous., chloroform, ethanol and acetone extracts of leaves
#14: saponins in petroleum ether and , chloroform extracts of leaves.
#15: alkaloids in aqueous, petroleum ether, choloroform, ethanol and acetone extracts of leaves
#16: diterpene clerodin in aerial parts
#17: alkaloids in leaves
#18: saponins in leaves
#19: sterols in aerial parts
#20: sterols in leaves
#21: myrcene in leaves
#22: Acacetin 7-O-alpha-L-rhamnopyranoside in flower
#23: tannins in leaves
#24: myrcene in roots
#25: Acacetin 7-O-alpha-L-rhamnopyranoside in roots.
Composition #1: Sultana, Nasim., Akanda, Shafiqul Islam., Bhuiyan, Rauf Ahmed., Bagum, Shameem Ara., Kazi, M. Azizul Islam., Sharkar, Abdul Mannan. A neo-clerodane diterpenoid from Clerodendrum viscosum leaves. bangladesh journal of scientific and industrial research, 2005, vol. 40(3-4), p. 337–341. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
The petroleum ether ext. of the leaves
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Substance:
clerodane-type diterpenes (RF-00004350-PAR)
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Additional substance description:
neo-clerodane diterpenoids
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
neo-clerodane diterpenoids in leaves (leaf juice is used as a strong anthelmintic, emetic, mild laxative and cholagogue)
Composition #2: Azad, A. K., Wan Azizi, W. S., Syafiq, T. M. F., Mahmood, S., Almoustafa, H. A., Labu, Z. K. Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. australian journal of basic and applied sciences, 2013, vol. 7, no. 4, p. 641–647. .
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-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
barks of the root were powdered and immersed in ethanolic extract in Soxhlate apparatus
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Saponins in the root bark
Composition #3: Azad, A. K., Wan Azizi, W. S., Syafiq, T. M. F., Mahmood, S., Almoustafa, H. A., Labu, Z. K. Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. australian journal of basic and applied sciences, 2013, vol. 7, no. 4, p. 641–647. .
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-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
barks of the root were powdered and immersed in ethanolic extract in Soxhlate apparatus
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alkaloids in the root bark
Composition #4: Azad, A. K., Wan Azizi, W. S., Syafiq, T. M. F., Mahmood, S., Almoustafa, H. A., Labu, Z. K. Isolation, characterization and cytotoxic effect exploration of methanolic extract of local medicinal plant clerodendrumn viscosum vent. australian journal of basic and applied sciences, 2013, vol. 7, no. 4, p. 641–647. .
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
barks of the root were powdered and immersed in ethanolic extract in Soxhlate apparatus
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Tannins in the root bark
Composition #5: Ray, S., Kundu, L. M., Goswami, S., Roy, G. C., Chatterjee, S., Dutta, S., Chaudhuri, A., Chakrabarti, C. S. Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. cell proliferation, 2013, vol. 46, no. 1, p. 109–117. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water
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Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Saponins are present in the water extract of leaves.
Composition #6: Ray, S., Kundu, L. M., Goswami, S., Roy, G. C., Chatterjee, S., Dutta, S., Chaudhuri, A., Chakrabarti, C. S. Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. cell proliferation, 2013, vol. 46, no. 1, p. 109–117. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Additional substance description:
traces of alkaloids
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Alcaloids (traces) are present in the water extract of leaves
Composition #7: Ray, S., Kundu, L. M., Goswami, S., Roy, G. C., Chatterjee, S., Dutta, S., Chaudhuri, A., Chakrabarti, C. S. Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. cell proliferation, 2013, vol. 46, no. 1, p. 109–117. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Tannins are present in the water extract of leaves..
Composition #8: Islam, Rafiquel., Rahman, Atiqur. A GC-MS study: Identification of the essential oil compositions of Clerodendrum viscosum vent flower. journal of essential oil-bearing plants, 2015, vol. 18, no. 5, p. 1271–1274. .
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Plant part:
Flower (as part-nature) (A067B)
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Extraction/Preparation method:
Essential oil (as part-nature) (A166Q)
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Additional extraction description:
hydrodistillation
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Substance:
benzoquinones (RF-00010840-PAR)
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Additional substance description:
Tert-butyl-p-benzoquinone
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
2.03
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Internal remarks:
Tert-butyl-p-benzoquinone in flowers
Composition #9: Panda, Pritipadma., Rath, Meera., Pal, Abhisek., Sharma, Tripti., Das, Debajyoti. GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves. pharmacognosy research, 2015, vol. 7, no. 1), 110-11, p. 4 pp. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
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Substance:
Hydroxymethylfurfural (RF-00000379-ORG)
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Additional substance description:
5‑Hydroxymethylfurfural together with other 15 phytoconsituents
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
7.11
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Internal remarks:
5‑Hydroxymethylfurfural in leaves
Composition #10: Panda, Pritipadma., Rath, Meera., Pal, Abhisek., Sharma, Tripti., Das, Debajyoti. GC-MS analysis of bioactive compounds in the methanol extract of Clerodendrum viscosum leaves. pharmacognosy research, 2015, vol. 7, no. 1), 110-11, p. 4 pp. .
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-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
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Substance:
Benzofuran (RF-00011196-PAR)
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Additional substance description:
Benzofuran, 2,3‑dihydro‑Heterocyclic aromatic together with other 15 phytoconsituents
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Analytical method code:
GC-MS (F046A)
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
3.52
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Internal remarks:
Benzofuran, 2,3‑dihydro‑Heterocyclic aromatic in leaves
Composition #11: Kale, Anand., Maniyar, Yasmeen A. "Evaluation of anti-inflammatory activity of ethanolic extract of clerodendrum infortunatum Linn-in rats". world journal of pharmaceutical research, 2015, vol. 4, no. 9, p. 942–952. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
saponin
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponin in leaves
Composition #12: Kale, Anand., Maniyar, Yasmeen A. "Evaluation of anti-inflammatory activity of ethanolic extract of clerodendrum infortunatum Linn-in rats". world journal of pharmaceutical research, 2015, vol. 4, no. 9, p. 942–952. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
Methanol
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannin in leaves
Composition #13: Florence, A.R., Joselin, J., Jeeva, S. Intra-specific variation of bioactive principles in select members of the genus Clerodendrum L. journal of chemical and pharmaceutical research, 2012, vol. 4, no. 11, p. 4908–4914. .
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-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water, chloroform, ethanol and acetone
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Substance:
Quinones (RF-00010832-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
quinones in aqueous., chloroform, ethanol and acetone extracts of leaves
Composition #14: Florence, A.R., Joselin, J., Jeeva, S. Intra-specific variation of bioactive principles in select members of the genus Clerodendrum L. journal of chemical and pharmaceutical research, 2012, vol. 4, no. 11, p. 4908–4914. .
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-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether, chloroform
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Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins in petroleum ether and , chloroform extracts of leaves.
Composition #15: Florence, A.R., Joselin, J., Jeeva, S. Intra-specific variation of bioactive principles in select members of the genus Clerodendrum L. journal of chemical and pharmaceutical research, 2012, vol. 4, no. 11, p. 4908–4914. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water, petroleum ether, chloroform, ethanol and acetone
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Phytochemical screening (F604A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloids in aqueous, petroleum ether, choloroform, ethanol and acetone extracts of leaves
Composition #16: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Substance:
clerodane-type diterpenes (RF-00004350-PAR)
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Additional substance description:
diterpene clerodin
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
diterpene clerodin in aerial parts
Composition #17: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Substance:
Alkaloids (RF-00004360-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloids in leaves
Composition #18: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins in leaves
Composition #19: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
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Plant part:
Aerial part of plants (as part-nature) (A166F)
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Substance:
sterols, total sterols, total (RF-00000402-NTR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
sterols in aerial parts
Composition #20: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Substance:
sterols, total sterols, total (RF-00000402-NTR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
sterols in leaves
Composition #21: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Substance:
myrcene (RF-00003503-PAR)
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Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
myrcene in leaves
Composition #22: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Flower (as part-nature) (A067B)
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Substance:
Acacetin 7-O-alpha-L-rhamnopyranoside Acacetin 7-O-alpha-L-rhamnopyranoside (RF-00011483-PAR)
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Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Acacetin 7-O-alpha-L-rhamnopyranoside in flower
Composition #23: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannins in leaves
Composition #24: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Substance:
myrcene (RF-00003503-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
myrcene in roots
Composition #25: Nandi, Suranjana., Lyndem, Larisha Mawkhlieng. Clerodendrum viscosum: traditional uses, pharmacological activities and phytochemical constituents . natural product research, 2016, vol. 30, no. 5, p. 497–506. DOI: 10.1080/14786419.2015.1025229.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Substance:
Acacetin 7-O-alpha-L-rhamnopyranoside Acacetin 7-O-alpha-L-rhamnopyranoside (RF-00011483-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Acacetin 7-O-alpha-L-rhamnopyranoside in roots.
Genotox #1: Ray, S., Kundu, L. M., Goswami, S., Roy, G. C., Chatterjee, S., Dutta, S., Chaudhuri, A., Chakrabarti, C. S. Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. cell proliferation, 2013, vol. 46, no. 1, p. 109–117. .
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Study category:
Genotoxicity
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Type of toxicological test:
micronucleus assay (CHD051TT)
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-
Tested organism:
House mouse (as animal) (A0CNT)
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Route of exposure:
OTHER (OECD0PL)
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Exposure duration for in vivo:
300.0
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Unit of exposure duration:
Milligram/kilogram (G061A)
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Number of organisms dosed:
6
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-
-
Remarks on genotox study:
The leaf aqueous extract of C. infortunatum induced un mouse bone marrow cells metapase arrest.
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Internal remarks:
a dose of 300 mg/kg b.w. of the leaf aqueous extract of C. infortunatum induced un mouse bone marrow cells metaphase arrest
-