EFSA Compendium of Botanicals

Draft - work in progress

Cinnamomum camphora (L.) J.Presl.

Family:: Lauraceae
Approval state:: Approved
Number of articles retrieved:: 2080
Number of processed references:: 4

Compositions

#1: camphor in fresh leaves #2: safrole in roots #3: elemicin in roots #4: 1,8-cineole in roots #5: camphor in roots #6: myrcene in leaves #7: 1,8-cineole in leaves #8: 1,8-cineole in fruit #9: 1,8-cineole in wood #10: camphor in leaves #11: camphor in fruit #12: camphor in wood #13: myrcene in wood #14: safrole in wood #15: safrole in roots #16: safrole in fruit #17: camphor in unspecified part #18: cineole in unspecified part #19: safrole in unspecified part

Endpoint Studies

Genotoxicity

Composition #1: Wahid, M. A., Samiullah. Standardization of active principles of indigenous pharmacopoeial drugs found in West Pakistan. pakistan journal of scientific and industrial research, 1960, vol. 3, p. 228–30. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

unspecified
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.60
Internal remarks:

camphor in fresh leaves

Composition #2: Yang, Bi-xian., Hu, Qi-zhi., Hu, Xin., Yun, Xue-lin. Chemical constituents of the volatile oil from the root of Cinnamomum camphora by supercritical carbon dioxide fluid extraction by gas chromatography-mass spectrometry. zhongguo shiyan fangjixue zazhi, 2012, vol. 18, no. 22, p. 127–131. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

supercrit. carbon dioxide fluid extn. (SFE)
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

29.44
Internal remarks:

safrole in roots

Composition #3: Yang, Bi-xian., Hu, Qi-zhi., Hu, Xin., Yun, Xue-lin. Chemical constituents of the volatile oil from the root of Cinnamomum camphora by supercritical carbon dioxide fluid extraction by gas chromatography-mass spectrometry. zhongguo shiyan fangjixue zazhi, 2012, vol. 18, no. 22, p. 127–131. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

supercrit. carbon dioxide fluid extn. (SFE)
Substance:

elemicin (RF-00003787-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

23.58
Internal remarks:

elemicin in roots

Composition #4: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.4 - 26
Internal remarks:

1,8-cineole in roots

Composition #5: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

26.5 - 55.6
Internal remarks:

camphor in roots

Composition #6: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.8 - 3.3
Internal remarks:

myrcene in leaves

Composition #7: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

47 - 53.4
Internal remarks:

1,8-cineole in leaves

Composition #8: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

53.3
Internal remarks:

1,8-cineole in fruit

Composition #9: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.2 - 43.9
Internal remarks:

1,8-cineole in wood

Composition #10: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

57 - 72.5
Internal remarks:

camphor in leaves

Composition #11: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.1
Internal remarks:

camphor in fruit

Composition #12: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.2 - 67.6
Internal remarks:

camphor in wood

Composition #13: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2 - 3
Internal remarks:

myrcene in wood

Composition #14: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Wood (as part-nature) (A166P)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.8 - 5
Internal remarks:

safrole in wood

Composition #15: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.8 - 23.3
Internal remarks:

safrole in roots

Composition #16: Stubbs, BJ., Specht, A., Brushett, D. The essential oil of Cinnamomum camphora (L.) Nees and Eberm. - Variation in oil composition throughout the tree in two chemotypes from Eastern Australia . journal of essential oil research, 2004, vol. 16, no. 1, p. 9–14. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

acetone
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-FID (F040A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.6
Internal remarks:

safrole in fruit

Composition #17: Fu, J. T., Tang, L., Li, W. S., Wang, K., Cheng, D. M., Zhang, Z. X. Fumigant Toxicity and Repellence Activity of Camphor Essential Oil from Cinnamonum camphora Siebold Against Solenopsis invicta Workers (Hymenoptera:Formicidae) . journal of insect science, 2015, vol. 15 . DOI: 10.1093/jisesa/iev112. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

36.61
Internal remarks:

camphor in unspecified part

Composition #18: Fu, J. T., Tang, L., Li, W. S., Wang, K., Cheng, D. M., Zhang, Z. X. Fumigant Toxicity and Repellence Activity of Camphor Essential Oil from Cinnamonum camphora Siebold Against Solenopsis invicta Workers (Hymenoptera:Formicidae) . journal of insect science, 2015, vol. 15 . DOI: 10.1093/jisesa/iev112. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Additional substance description:

cineole
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

30.02
Internal remarks:

cineole in unspecified part

Composition #19: Fu, J. T., Tang, L., Li, W. S., Wang, K., Cheng, D. M., Zhang, Z. X. Fumigant Toxicity and Repellence Activity of Camphor Essential Oil from Cinnamonum camphora Siebold Against Solenopsis invicta Workers (Hymenoptera:Formicidae) . journal of insect science, 2015, vol. 15 . DOI: 10.1093/jisesa/iev112. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.15
Internal remarks:

safrole in unspecified part