EFSA
ecomole
vscht
  2. Chondrodendron platyphyllum (A.St.-Hil.) Miers

Chondrodendron platyphyllum (A.St.-Hil.) Miers

Family:
Menispermaceae
Approval state:
Approved
Number of articles retrieved:
20
Number of processed references:
6
Compositions
#1: Curare alkaloids #2: Chondrofoline and derivatives from leaves #3: chondrofoline from leaves #4: L-Bebeerine from roots #5: 12-O-Methylcurine from the root bark #6: Bisbenzylisoquinoline alkaloids in roots
Endpoint Studies
Genotoxicity
Composition #1: Brazil, Oswaldo V., Seba, Roched A., Campos, Joao S. Curarizing properties of the alkali-insoluble methylated alkaloids of Chondrodendron platyphyllum (St. Hil.) Miers. bol. inst. vital brazil, 1944, vol. No. 26, p. 8–22. .
Composition #2: Bick, I. R. C., Baldas, J., Porter, Q. N., Vernengo, M. J. Structure and stereochemistry of the alkaloid chondrofoline. journal of the chemical society [section] d: chemical communications, 1971, vol. (3), p. 132–3. .
Composition #3: King, H. Curare alkaloids. Part V. Alkaloids of some chondrodendron species and the origin of radix pareiræ bravæ. journal of the chemical society (resumed), 1940, p. 737–746. DOI: 10.1039/JR9400000737. [DOI link]
Composition #4: Souccar, C., Borras, M R., Corrado, A P., Lima-Landman, M T., Lapa, A J. Natural probes for cholinergic sites: L-bebeerine actions on the neuromuscular transmission, the nicotinic receptor/ionic channel complex, and contraction of skeletal muscles. . acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la asociacion latinoamericana de ciencias fisiologicas y [de] la asociacion latinoamericana de farmacologia, 1999, vol. 49, no. 4, p. 268–78. .
Composition #5: Guedes, DN., Barbosa, JM., Lemos, VS., Cortes, SF. Mechanism of the vasodilator effect of 12-O-methylcurine in rat aortic rings . journal of pharmacy and pharmacology, 2002, vol. 54, no. 6, p. 853–858. DOI: 10.1211/0022357021779032. [DOI link]
Composition #6: Leite, Fagner Carvalho., Ribeiro-Filho, Jaime., Costa, Hermann Ferreira., Rodrigues Salgado, Paula Regina., Calheiros, Andrea Surrage., Carneiro, Alan Brito., de Almeida, Reinaldo Nobrega., Dias, Celidarque da Silva., Bozza, Patricia T., Piuvezam, Marcia Regina. Curine, an Alkaloid Isolated from Chondrodendron platyphyllum Inhibits Prostaglandin E-2 in Experimental Models of Inflammation and Pain . planta medica, 2014, vol. 80, no. 13, p. 1072–1078. DOI: 10.1055/s-0034-1382997. [DOI link]