EFSA Compendium of Botanicals

Draft - work in progress

Chaenomeles speciosa (Sweet) Nakai

Family:: Rosaceae
Approval state:: Approved
Number of articles retrieved:: 280
Number of processed references:: 1

Compositions

#1: saponins in fruit #2: Chlorogenic acid in fruit #3: p-coumaric acid in fruit #4: gallic acid in fruit

Endpoint Studies

#1: Alpha-glucosidase inhibition (IC50 1.32-2.66 mg dry weight per mL)

Genotoxicity

Composition #1: Miao, Jing., Zhao, Chengcheng., Li, Xia., Chen, Xuetao., Mao, Xinhui., Huang, Hanhan., Wang, Tingting., Gao, Wenyuan. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis . journal of food science, 2016, vol. 81, no. 8, p. H2049–H2058. DOI: 10.1111/1750-3841.13377. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Milligram-equivalent/gram (G261A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

44.13-60.61
Internal remarks:

saponins in fruit

Composition #2: Miao, Jing., Zhao, Chengcheng., Li, Xia., Chen, Xuetao., Mao, Xinhui., Huang, Hanhan., Wang, Tingting., Gao, Wenyuan. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis . journal of food science, 2016, vol. 81, no. 8, p. H2049–H2058. DOI: 10.1111/1750-3841.13377. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Chlorogenic acid (RF-00010714-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

172.19-236.08
Internal remarks:

Chlorogenic acid in fruit

Composition #3: Miao, Jing., Zhao, Chengcheng., Li, Xia., Chen, Xuetao., Mao, Xinhui., Huang, Hanhan., Wang, Tingting., Gao, Wenyuan. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis . journal of food science, 2016, vol. 81, no. 8, p. H2049–H2058. DOI: 10.1111/1750-3841.13377. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

p-coumaric acid (RF-00010717-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

16.93-124.76
Internal remarks:

p-coumaric acid in fruit

Composition #4: Miao, Jing., Zhao, Chengcheng., Li, Xia., Chen, Xuetao., Mao, Xinhui., Huang, Hanhan., Wang, Tingting., Gao, Wenyuan. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis . journal of food science, 2016, vol. 81, no. 8, p. H2049–H2058. DOI: 10.1111/1750-3841.13377. [DOI link]

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

gallic acid (RF-00003821-PAR)
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

17.37-99.75
Internal remarks:

gallic acid in fruit

Endpoint study #1: Miao, Jing., Zhao, Chengcheng., Li, Xia., Chen, Xuetao., Mao, Xinhui., Huang, Hanhan., Wang, Tingting., Gao, Wenyuan. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis . journal of food science, 2016, vol. 81, no. 8, p. H2049–H2058. DOI: 10.1111/1750-3841.13377. [DOI link]

Study relevance:

Human health
Plant part:

Fruit unspecified (as part-nature) (A067D)
Preparation/Extraction method:

Solvent extraction (A0BZR)
Additional plant/substance description:

methanol
Type of toxicological test:

in vitro (CHD061TT)
Control groups used:

yes
Endpoint measured:

Half maximal inhibitory concentration (CHD021EP)
Concentration unit:

Milligram/millilitre (G191A)
Effect concentration:

1.32-2.66
Critical effect:

Digestive (TOX18A)
Target tissue:

digestive: Pancreas (TT024A)
Effect description:

Alpha-glucosidase inhibition
Effect or parameter linked to the endpoint:

enzyme inhibition (CHD032BE)
Internal remarks:

Alpha-glucosidase inhibition (IC50 1.32-2.66 mg dry weight per mL)