EFSA
ecomole
vscht
  2. Catharanthus roseus (L.) G.Don.

Catharanthus roseus (L.) G.Don.

Family:
Apocynaceae
Approval state:
Approved
Number of articles retrieved:
7997
Number of processed references:
6
Compositions
#1: vindesine, vinorelbine #2: Indole alkaloids in roots #3: Indole alkaloids in leaves #4: catharanthine, serpentine, strictosidine, vindoline in roots #5: ajmalicine in roots #6: vinblastine in roots #7: vincristine in roots #8: catharanthine in leaves #9: vinblastine in leaves #10: vindoline in leaves
Endpoint Studies
#1: case reports
Genotoxicity
#1: positive gene mutation essay - strains TA98 and TA 100
Composition #1: Rao, C.V., Kurkjian, C.D., Yamada, H.Y. Mitosis-targeting natural products for cancer prevention and therapy. current drug targets, 2012, vol. 13, no. 14, p. 1820–1830. DOI: 10.2174/138945012804545533. [DOI link]
Composition #2: Alam, M. Masidur., Naeem, M., Idrees, M., Khan, M. Masroor A., Moinuddin. Augmentation of Photosynthesis, Crop Productivity, Enzyme Activities and Alkaloids Production in Sadabahar (Catharanthus roseus L.) through Application of Diverse Plant Growth Regulators. journal of crop science and biotechnology, 2012, vol. 15, no. 2, p. 117–129. DOI: 10.1007/s12892-011-0005-7. [DOI link]
Composition #3: Alam, M. Masidur., Naeem, M., Idrees, M., Khan, M. Masroor A., Moinuddin. Augmentation of Photosynthesis, Crop Productivity, Enzyme Activities and Alkaloids Production in Sadabahar (Catharanthus roseus L.) through Application of Diverse Plant Growth Regulators. journal of crop science and biotechnology, 2012, vol. 15, no. 2, p. 117–129. DOI: 10.1007/s12892-011-0005-7. [DOI link]
Composition #4: Yang, Liuqing., Stoeckigt, Joachim. Trends for diverse production strategies of plant medicinal alkaloids. natural product reports, 2010, vol. 27, no. 10, p. 1469–1479. DOI: 10.1039/c005378c. [DOI link]
Composition #5: Yang, Liuqing., Stoeckigt, Joachim. Trends for diverse production strategies of plant medicinal alkaloids. natural product reports, 2010, vol. 27, no. 10, p. 1469–1479. DOI: 10.1039/c005378c. [DOI link]
Composition #6: Yang, Liuqing., Stoeckigt, Joachim. Trends for diverse production strategies of plant medicinal alkaloids. natural product reports, 2010, vol. 27, no. 10, p. 1469–1479. DOI: 10.1039/c005378c. [DOI link]
Composition #7: Yang, Liuqing., Stoeckigt, Joachim. Trends for diverse production strategies of plant medicinal alkaloids. natural product reports, 2010, vol. 27, no. 10, p. 1469–1479. DOI: 10.1039/c005378c. [DOI link]
Composition #8: Liu, Ying., Zhao, Dong-Mei., Zu, Yuan-Gang., Tang, Zhong-Hua., Zhang, Zhong-Hua., Jiang, Yang., Shi, Dian-Yi. Effects of low light on terpenoid indole alkaloid accumulation and related biosynthetic pathway gene expression in leaves of Catharanthus roseus seedlings. botanical studies, 2011, vol. 52, no. 2, p. 191–196. .
Composition #9: Liu, Ying., Zhao, Dong-Mei., Zu, Yuan-Gang., Tang, Zhong-Hua., Zhang, Zhong-Hua., Jiang, Yang., Shi, Dian-Yi. Effects of low light on terpenoid indole alkaloid accumulation and related biosynthetic pathway gene expression in leaves of Catharanthus roseus seedlings. botanical studies, 2011, vol. 52, no. 2, p. 191–196. .
Composition #10: Liu, Ying., Zhao, Dong-Mei., Zu, Yuan-Gang., Tang, Zhong-Hua., Zhang, Zhong-Hua., Jiang, Yang., Shi, Dian-Yi. Effects of low light on terpenoid indole alkaloid accumulation and related biosynthetic pathway gene expression in leaves of Catharanthus roseus seedlings. botanical studies, 2011, vol. 52, no. 2, p. 191–196. .
Endpoint study #1: Serrano, Rita. Toxic plants: knowledge, medicinal uses and potential human health risks. environment and ecology research, 2018, vol. 6, no. 5, p. 487–492. .
Genotox #1: Ramulondi, Mmbulaheni., de Wet, Helene., van Vuuren, Sandy. Toxicology of medicinal plants and combinations used in rural northern KwaZulu-Natal (South Africa) for the treatment of hypertension. journal of herbal medicine, 2019, vol. 16 . DOI: 10.1016/j.hermed.2018.12.001. [DOI link]