Composition #1: Chowdhury, A. R. GC-MS studies on essential oil from Carum carvi L. raised in Kumaon. journal of essential oil-bearing plants, 2002, vol. 5, no. 3, p. 158–161. .
        
    
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Essential oil (as part-nature) (A166Q)
             
 
 
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                Additional extraction description:
             
                Steam distillation
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Additional substance description:
             
                Concentration given is in essential oil (3.5% oil on dry wt. basis)
             
 
 
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                Analytical method code:
             
                GC-MS (F046A)
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                81.5
             
 
 
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                Internal remarks:
             
                Carvone
             
 
 
 
    Composition #2: Semenov, V. V., Rusak, V. V., Chartov, E. M., Zaretskii, M. I., Konyushkin, L. D., Firgang, S. I., Chizhov, A. O., Elkin, V. V., Latin, N. N., Bonashek, V. M., . Polyalkoxybenzenes from plant raw materials. 1. Isolation of polyalkoxybenzenes from CO2 extracts of Umbelliferae plant seeds. russian chemical bulletin, 2007, vol. 56, no. 12, p. 2448–2455. .
        
    
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Super-critical gas extraction (A0BZQ)
             
 
 
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                Additional extraction description:
             
                CO2 Extraction
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Analytical method code:
             
                GC-MS (F046A)
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                49.3
             
 
 
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                Internal remarks:
             
                Carvone (seeds)
             
 
 
 
    Composition #3: Dhalwal, Kamlesh., Shinde, Vaibhav M., Mahadik, Kakasaheb R. Efficient and sensitive method for quantitative determination and validation of umbelliferone, carvone and myristicin in Anethum graveolens and Carum carvi seed . chromatographia, 2008, vol. 67, no. 1-2, p. 163–167. DOI: 10.1365/s10337-007-0473-6.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Solvent extraction (A0BZR)
             
 
 
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                Additional extraction description:
             
                Methanol
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Analytical method code:
             
                Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
             
 
 
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                Analytical method - additional description:
             
                HPTLC
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result expression:
             
                Dry matter (B002A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                0.019-0.05
             
 
 
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                Internal remarks:
             
                Carvone
             
 
 
 
    Composition #4: Dhalwal, Kamlesh., Shinde, Vaibhav M., Mahadik, Kakasaheb R. Efficient and sensitive method for quantitative determination and validation of umbelliferone, carvone and myristicin in Anethum graveolens and Carum carvi seed . chromatographia, 2008, vol. 67, no. 1-2, p. 163–167. DOI: 10.1365/s10337-007-0473-6.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Solvent extraction (A0BZR)
             
 
 
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                Additional extraction description:
             
                Methanol
             
 
 
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                Substance:
             
                umbelliferone (RF-00004096-PAR)
             
 
 
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                Analytical method code:
             
                Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
             
 
 
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                Analytical method - additional description:
             
                HPTLC
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result expression:
             
                Dry matter (B002A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                0.0017-0.0041
             
 
 
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                Internal remarks:
             
                Umbelliferone
             
 
 
 
    Composition #5: Dhalwal, Kamlesh., Shinde, Vaibhav M., Mahadik, Kakasaheb R. Efficient and sensitive method for quantitative determination and validation of umbelliferone, carvone and myristicin in Anethum graveolens and Carum carvi seed . chromatographia, 2008, vol. 67, no. 1-2, p. 163–167. DOI: 10.1365/s10337-007-0473-6.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Solvent extraction (A0BZR)
             
 
 
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                Additional extraction description:
             
                Methanol
             
 
 
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                Substance:
             
                myristicin (RF-00003941-PAR)
             
 
 
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                Analytical method code:
             
                Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
             
 
 
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                Analytical method - additional description:
             
                HPTLC
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result expression:
             
                Dry matter (B002A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                0.016-0.033
             
 
 
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                Internal remarks:
             
                Myristicin
             
 
 
 
    Composition #6: Park, Il-Kwon., Kim, Junheo N., Lee, Yeon-Suk., Lee, Sang-Gil., Ahn, Young-Joon., Shin, Sang-Chul. Toxicity of plant essential oils and their components against Lycoriella ingenua (Diptera : Sciaridae) . journal of economic entomology, 2008, vol. 101, no. 1, p. 139–144. DOI: 10.1603/0022-0493(2008)101[139:TOPEOA]2.0.CO;2.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Seed (as part-nature) (A066P)
             
 
 
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                Extraction/Preparation method:
             
                Essential oil (as part-nature) (A166Q)
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Additional substance description:
             
                The concentration values are for essential oil
             
 
 
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                Analytical method code:
             
                Gaschromatography (GC) (F037A)
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                53.6
             
 
 
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                Internal remarks:
             
                carvone (seeds)
             
 
 
 
    Composition #7: Raal, Ain., Arak, Elmar., Orav, Anne. The content and composition of the essential oil Found in Carum carvi L. commercial fruits obtained from different countries . journal of essential oil research, 2012, vol. 24, no. 1, p. 53–59. DOI: 10.1080/10412905.2012.646016.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Fruit unspecified (as part-nature) (A067D)
             
 
 
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                Extraction/Preparation method:
             
                Essential oil (as part-nature) (A166Q)
             
 
 
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                Additional extraction description:
             
                water, distillation
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Additional substance description:
             
                Concentration given is in essential oil
             
 
 
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                Analytical method code:
             
                Gaschromatography (GC) (F037A)
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                44.5-95.9
             
 
 
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                Internal remarks:
             
                Carvone (fruit)
             
 
 
 
    Composition #8: Synowiec, A., Kalemba, D., Drozdek, E., Bocianowski, J. Phytotoxic potential of essential oils from temperate climate plants against the germination of selected weeds and crops . journal of pest science, 2017, vol. 90, no. 1, p. 407–419. DOI: 10.1007/s10340-016-0759-2.
        [
DOI link]
    
 
  
    
  
  
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                Plant part:
             
                Fruit unspecified (as part-nature) (A067D)
             
 
 
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                Extraction/Preparation method:
             
                Essential oil (as part-nature) (A166Q)
             
 
 
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                Additional extraction description:
             
                Hydrodistillation
             
 
 
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                Substance:
             
                Carvone (RF-0538-001-PPP)
             
 
 
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                Additional substance description:
             
                Concentration given is in essential oil
             
 
 
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                Analytical method code:
             
                GC-MS (F046A)
             
 
 
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                Result unit:
             
                Percent (G138A)
             
 
 
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                Result type:
             
                Numerical Value (VAL)
             
 
 
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                Value (concentration, content):
             
                63.2
             
 
 
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                Internal remarks:
             
                Carvone (fruit)
             
 
 
 
  Genotox #1: Mahmoud, I., Alkofahi, A., Abdelaziz, A. Mutagenic and toxic activities of several spices and some jordanian medicinal plants. pharmaceutical biology, 1992, vol. 30, no. 2, p. 81–85. DOI: 10.3109/13880209209053961.
        [
DOI link]
  
 
  
    
  
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                Study category:
             
                Mutagenicity
             
 
 
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                Type of toxicological test:
             
                bacterial reverse mutation assay (CHD028TT)
             
 
 
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                Tested organism:
             
                Salmonella typhimurium (as organism) (A0CPZ)
             
 
 
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                Strain of test organism:
             
                TA 102 (CHD025ST)
             
 
 
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                Exogenous metabolic activation applied:
             
                no data
             
 
 
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                Control groups used:
             
                no data
             
 
 
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                Remarks on genotox study:
             
                Positive mutagenic activity of 95% ethanol extract in bacterial Ames test in Salmonella typhimurium (TA102 strain)
             
 
 
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                Internal remarks:
             
                Positive mutagenic activity of 95% ethanol extract in bacterial Ames test in Salmonella typhimurium (TA102 strain).
             
 
 
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                Internal ID:
             
                eid=2-s2.0-84907105429