EFSA
ecomole
vscht
  2. Cannabis indica Lam.

Cannabis indica Lam.

Family:
Cannabaceae
Approval state:
Approved
Number of articles retrieved:
11773
Number of processed references:
8
Compositions
#1: cannabigerol #2: cannabinolic acid, cannabicyclol #3: delta-9-tetrahydrocannabinol in leaves and flowering tops #4: cannabinol #5: cannabidiol #6: Cannabinoids in resin (quantitative) #7: delta 9-tetrahydrocannabinol (THC) in resin (quantitative) #8: Cannabinol in resin (quantitative) #9: Cannabidiol in resin (quantitative) #10: delta-9-Tetrahydrocannabinol resins #11: cannabinol resins #12: cannabigerol resins #13: cannabidiol resins #14: cannaigerl resins #15: tetrahydrocannabivarin resins #16: cannabichromene resins #17: hexahydrocannabinol resins #18: carvone aerial parts gc-ms #19: myrcene aerial parts gc-ms #20: Cannabinoids (96% CBD , < 1% THC) #21: cannabichromene in aerial parts
Endpoint Studies
#1: gidiness, sleepiness, eye deviation (ocular movements were absent) #2: Neurotoxicity #3: decreased body weight, heamatological and biochemical changes, organ weight and histopathological findings at dose level 1000 mg/kg/b.w. #4: mortality at dose level 3000/4000 mg/kg/b.w. #5: Subchronic toxicity: NOAEL - 100 mg/kg/b.w. for males and 360 mg/kg/b.w. for females #6: Aggressive behavior in both dosed male and female rats. Other clinical findings: sensitivity to touch, convulsions, lethargy, diarrhea, and tremors, especially in the 150 and 500 mg/kg groups. #7: Uterine atrophy and ovarian hypoplasia with the 150 and 500 mg/kg groups. Ovarian hypoplasia with a decrease in the size of maturing follicles. Estrous cycle lengths of the 15, 50, 150, and 500mg/kg females significantly longer than in controls
Genotoxicity
Composition #1: Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. addiction biology, 1999, vol. 4, no. 1, p. 5–12. .
Composition #2: Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. addiction biology, 1999, vol. 4, no. 1, p. 5–12. .
Composition #3: Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. addiction biology, 1999, vol. 4, no. 1, p. 5–12. .
Composition #4: Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. addiction biology, 1999, vol. 4, no. 1, p. 5–12. .
Composition #5: Marselos, Marios., Karamanakos, Petros. Mutagenicity, developmental toxicity and carcinogenicity of cannabis. addiction biology, 1999, vol. 4, no. 1, p. 5–12. .
Composition #6: Qureshi, Muhammad Nasimullah., Kanwal, Farina., Siddique, Muhammad., Inayat-ur-Rahman., Akram, Muhammad. Estimation of biologically active Cannabinoids in Cannabis indica by gas chromatography-mass spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. .
Composition #7: Qureshi, Muhammad Nasimullah., Kanwal, Farina., Siddique, Muhammad., Inayat-ur-Rahman., Akram, Muhammad. Estimation of biologically active Cannabinoids in Cannabis indica by gas chromatography-mass spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. .
Composition #8: Qureshi, Muhammad Nasimullah., Kanwal, Farina., Siddique, Muhammad., Inayat-ur-Rahman., Akram, Muhammad. Estimation of biologically active Cannabinoids in Cannabis indica by gas chromatography-mass spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. .
Composition #9: Qureshi, Muhammad Nasimullah., Kanwal, Farina., Siddique, Muhammad., Inayat-ur-Rahman., Akram, Muhammad. Estimation of biologically active Cannabinoids in Cannabis indica by gas chromatography-mass spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. .
Composition #10: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #11: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #12: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #13: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #14: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #15: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #16: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #17: Qureshi, M.N., Kanwal, F., Siddique, M., Inayat-ur-Rahman., Akram, M. Estimation of biologically active cannabinoids in Cannabis indica by Gas Chromatography-mass Spectrometry (GC-MS). world applied sciences journal, 2012, vol. 19, no. 7, p. 918–923. DOI: 10.5829/idosi.wasj.2012.19.07.1922. [DOI link]
Composition #18: Naz, Saima., Hanif, Muhammad Asif., Bhatti, Haq Nawaz., Ansari, Tariq Mahmood. Impact of Supercritical Fluid Extraction and Traditional Distillation on the Isolation of Aromatic Compounds from Cannabis indica and Cannabis sativa . journal of essential oil bearing plants, 2017, vol. 20, no. 1, p. 175–184. DOI: 10.1080/0972060X.2017.1281766. [DOI link]
Composition #19: Naz, Saima., Hanif, Muhammad Asif., Bhatti, Haq Nawaz., Ansari, Tariq Mahmood. Impact of Supercritical Fluid Extraction and Traditional Distillation on the Isolation of Aromatic Compounds from Cannabis indica and Cannabis sativa . journal of essential oil bearing plants, 2017, vol. 20, no. 1, p. 175–184. DOI: 10.1080/0972060X.2017.1281766. [DOI link]
Composition #20: Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. journal of toxicology, 2018 . DOI: 10.1155/2018/8143582. [DOI link]
Composition #21: Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. journal of toxicology, 2018 . DOI: 10.1155/2018/8143582. [DOI link]
Endpoint study #1: MOHAN, H., SOOD, G C. CONJUGATE DEVIATION OF THE EYES AFTER CANNABIS INDICA INTOXICATION.. the british journal of ophthalmology, 1964, vol. 48, p. 160–1. DOI: 10.1136/bjo.48.3.160. [DOI link]
Endpoint study #2: Favretto, Donata., Montisci, Massimo., Snenghi, Rossella., Andreazza, AC., Scola, G. Forensic Toxicology. toxicology studies - cells, drugs and environment, 2015, p. 85–100. DOI: 10.5772/60445. [DOI link]
Endpoint study #3: Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. journal of toxicology, 2018 . DOI: 10.1155/2018/8143582. [DOI link]
Endpoint study #4: Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. journal of toxicology, 2018 . DOI: 10.1155/2018/8143582. [DOI link]
Endpoint study #5: Marx, Tennille K., Reddeman, Robin., Clewell, Amy E., Endres, John R., Beres, Erzsebet., Vertesi, Adel., Glavits, Robert., Hirka, Gabor., Szakonyine, Ilona Pasics. An Assessment of the Genotoxicity and Subchronic Toxicity of a Supercritical Fluid Extract of the Aerial Parts of Hemp. journal of toxicology, 2018 . DOI: 10.1155/2018/8143582. [DOI link]
Endpoint study #6: Chan, PC., Sills, RC., Braun, AG., Haseman, JK., Bucher, JR. Toxicity and carcinogenicity of Delta(9)-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. fundamental and applied toxicology, 1996, vol. 30, no. 1, p. 109–117. DOI: 10.1006/faat.1996.0048. [DOI link]
Endpoint study #7: Chan, PC., Sills, RC., Braun, AG., Haseman, JK., Bucher, JR. Toxicity and carcinogenicity of Delta(9)-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. fundamental and applied toxicology, 1996, vol. 30, no. 1, p. 109–117. DOI: 10.1006/faat.1996.0048. [DOI link]