Draft - work in progress
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- Buxus sempervirens L.
Buxus sempervirens L.
- Family:
- Buxaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 733
- Number of processed references:
- 11
Compositions
#1: hydroquinone in leaves
#2: Tannins
#3: cyclobuxine
#4: coumarins
#5: Saponins
#6: lutein epoxide in buds
#7: Alkaloids in unspecified part
#8: steroidal alkaloids ((+)-semperviraminol, (+)-buxamine F, and (+)-17-oxocycloprotobuxine, (+)-buxoxybenzamine and (+)-buxapapillinine ) in roots
#9: Triterpene alkaloids (hyrcanone , hyrcanol hyrcatrienine N-b-dimethylcycloxobuxoviricine and hyrcamine , buxidin , buxandrine , buxabenzacinine , buxippine-K and E-buxenone )
#10: cyclobuxine-D in wood
#11: Buxozine-C in wood
#12: cyclovirobuxine- D 1 in wood
#13: Alkaloids in leaves
#14: L-cycloprotobuxine-C in leaves
#15: imperialine in leaves
#16: cyclobuxine-D in leaves
#17: Steroidal alkaloids (sempervirine, (- )-31-acetyl-cyclomicrophylline-A, ( -)-benzoylbuxidienine, (+)-buxamine-C, (+ )-buxabenzamidienine) in leaves
#18: Steroidal alkamines
#19: Steroidal alkaloids
Composition #1: Ghodsi, M. R., Netien, G. Presence of arbutoside in the leaves of Buxus sempervirens. bulletin des travaux de la societe de pharmacie de lyon, 1970, vol. 14, no. 4, p. 115–18. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
Hydroquinone (RF-00007127-PAR)
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
hydroquinone in leaves
Composition #2: Orazmuradov, G. M., Karryev, M. O. Chemical composition of Buxus sempervirens leaves. izvestiya akademii nauk turkmenskoi ssr, seriya biologicheskikh nauk, 1974, vol. (6), p. 71–3. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
Tannins (RF-00004337-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Tannins
Composition #3: Orazmuradov, G. M., Karryev, M. O. Chemical composition of Buxus sempervirens leaves. izvestiya akademii nauk turkmenskoi ssr, seriya biologicheskikh nauk, 1974, vol. (6), p. 71–3. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
cyclobuxine (RF-00004244-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
cyclobuxine
Composition #4: Orazmuradov, G. M., Karryev, M. O. Chemical composition of Buxus sempervirens leaves. izvestiya akademii nauk turkmenskoi ssr, seriya biologicheskikh nauk, 1974, vol. (6), p. 71–3. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
unspecified
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Substance:
coumarins (RF-00004351-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
coumarins
Composition #5: Orazmuradov, G. M., Karryev, M. O. Chemical composition of Buxus sempervirens leaves. izvestiya akademii nauk turkmenskoi ssr, seriya biologicheskikh nauk, 1974, vol. (6), p. 71–3. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Saponins
Composition #6: Garcia-Plazaola, Jose I., Hormaetxe, Koldobika., Hernandez, Antonio., Olano, Jose M., Becerril, Jose M. The lutein epoxide cycle in vegetative buds of woody plants. functional plant biology, 2004, vol. 31, no. 8, p. 815–823. .
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Plant part:
Bud (as part-nature) (A066Z)
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Additional extraction description:
unspecified
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Substance:
Lutein epoxide (RF-00011263-PAR)
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Analytical method code:
Fluorimetry, Nephelometry and Polarimetry (F011A)
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Result unit:
Millimole (G115A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
10
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Internal remarks:
lutein epoxide in buds
Composition #7: Brown, Jr., K.S., Kupchan, S.M. A convenient separation of alkaloid mixtures by partition chromatography, using an indicator in the stationary phase. journal of chromatography a, 1962, vol. 9, no. C, p. 71–80. .
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethylene dichloride-Skellysolve B-methanol-water / ethylene dichloride-Skellysolve B-methanol-water
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
Chromatographic tests (F015A)
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Analytical method - additional description:
Partition chromatography
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
1-35
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Internal remarks:
Alkaloids in unspecified part
Composition #8: Atta-ur-Rahman., Ata, A., Naz, S., Choudhary, MI., Sener, B., Turkoz, S. New steroidal alkaloids from the roots of Buxus sempervirens. journal of natural products, 1999, vol. 62, no. 5, p. 665–669. DOI: 10.1021/np980285h.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
(+)-semperviraminol, (+)-buxamine F, and (+)-17-oxocycloprotobuxine, (+)-buxoxybenzamine and (+)-buxapapillinine
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
UV, IR, MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
steroidal alkaloids ((+)-semperviraminol, (+)-buxamine F, and (+)-17-oxocycloprotobuxine, (+)-buxoxybenzamine and (+)-buxapapillinine ) in roots
Composition #9: Choudhary, M. Iqbal., Shahnaz, Salma., Parveen, Shehnaz., Khalid, Asaad., Mesaik, M. Ahmed., Ayatollahi, S. Abdul Majeed., Atta-ur-Rahman. New cholinesterase-inhibiting triterpenoid alkaloids from Buxus hyrcana. chemistry & biodiversity, 2006, vol. 3, no. 9, p. 1039–1052. DOI: 10.1002/cbdv.200690102.
[
DOI link]
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
triterpene alkaloids (RF-00013680-PAR)
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Additional substance description:
hyrcanone , hyrcanol hyrcatrienine N-b-dimethylcycloxobuxoviricine and hyrcamine , buxidin , buxandrine , buxabenzacinine , buxippine-K and E-buxenone
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Analytical method code:
Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Triterpene alkaloids (hyrcanone , hyrcanol hyrcatrienine N-b-dimethylcycloxobuxoviricine and hyrcamine , buxidin , buxandrine , buxabenzacinine , buxippine-K and E-buxenone )
Composition #10: Liu, Hai-Feng., Ji, Min., Cai, Jin. Short and efficient approach towards buxozine-C, an alkaloid from Buxus sempervirens . archiv der pharmazie, 2006, vol. 339, no. 12, p. 675–676. DOI: 10.1002/ardp.200600063.
[
DOI link]
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Plant part:
Wood (as part-nature) (A166P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
cyclobuxine-D
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
LC-MS
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Result unit:
Percent (G138A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Numerical Value (VAL)
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Value (concentration, content):
24
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Internal remarks:
cyclobuxine-D in wood
Composition #11: Liu, Hai-Feng., Ji, Min., Cai, Jin. Short and efficient approach towards buxozine-C, an alkaloid from Buxus sempervirens . archiv der pharmazie, 2006, vol. 339, no. 12, p. 675–676. DOI: 10.1002/ardp.200600063.
[
DOI link]
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-
Plant part:
Wood (as part-nature) (A166P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
Buxozine-C
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
LC-MS
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Buxozine-C in wood
Composition #12: Liu, Hai-Feng., Ji, Min., Cai, Jin. Short and efficient approach towards buxozine-C, an alkaloid from Buxus sempervirens . archiv der pharmazie, 2006, vol. 339, no. 12, p. 675–676. DOI: 10.1002/ardp.200600063.
[
DOI link]
-
-
Plant part:
Wood (as part-nature) (A166P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
cyclovirobuxine- D 1
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
LC-MS
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Result unit:
Percent (G138A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Numerical Value (VAL)
-
Value (concentration, content):
66
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Internal remarks:
cyclovirobuxine- D 1 in wood
Composition #13: Leuthardt, Florine L. G., Glauser, Gaetan., Baur, Bruno. Composition of alkaloids in different box tree varieties and their uptake by the box tree moth Cydalima perspectalis . chemoecology, 2013, vol. 23, no. 4, p. 203–212. DOI: 10.1007/s00049-013-0134-1.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
formic acid in water / formic acid in acetonitrile
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Substance:
Alkaloids (RF-00004360-PAR)
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Additional substance description:
cyclovirobuxine D, Buxaminol E, Buxtauine M, O-tigloylcyclovirobuxeine B, O30-benzoyl-16-deoxybuxidienine C, Cyclosuffrobuxinine M, Cyclobuxophylline O /M, Buxadienine
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Analytical method code:
HPLC-MS/MS (F698A)
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Analytical method - additional description:
UHPLC–QTOFMS
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Alkaloids in leaves
Composition #14: Eshonov, M. A., Turgunov, K. K., Tashkhodzhaev, B., Shakirov, R. Alkaloids of Buxus sempervirens, Crystal and Molecular Structure of Cyclobuxine-D and Imperialine . chemistry of natural compounds, 2014, vol. 49, no. 6, p. 1179–1182. DOI: 10.1007/s10600-014-0858-3.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
L-cycloprotobuxine-C
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
IR, PMR, 13C NMR, and mass spectra.
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
L-cycloprotobuxine-C in leaves
Composition #15: Eshonov, M. A., Turgunov, K. K., Tashkhodzhaev, B., Shakirov, R. Alkaloids of Buxus sempervirens, Crystal and Molecular Structure of Cyclobuxine-D and Imperialine . chemistry of natural compounds, 2014, vol. 49, no. 6, p. 1179–1182. DOI: 10.1007/s10600-014-0858-3.
[
DOI link]
-
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
imperialine (RF-00003437-PAR)
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
IR, PMR, 13C NMR, and mass spectra.
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
imperialine in leaves
Composition #16: Eshonov, M. A., Turgunov, K. K., Tashkhodzhaev, B., Shakirov, R. Alkaloids of Buxus sempervirens, Crystal and Molecular Structure of Cyclobuxine-D and Imperialine . chemistry of natural compounds, 2014, vol. 49, no. 6, p. 1179–1182. DOI: 10.1007/s10600-014-0858-3.
[
DOI link]
-
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
cyclobuxine-D
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
IR, PMR, 13C NMR, and mass spectra.
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
cyclobuxine-D in leaves
Composition #17: ATTAURRAHMAN., AHMED, D., ASIF, E., JAMAL, SA., CHOUDHARY, MI., SENER, B., TURKOZ, S. STEROIDAL ALKALOIDS FROM LEAVES OF BUXUS-SEMPERVIRENS. phytochemistry, 1991, vol. 30, no. 4, p. 1295–1298. .
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Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
-
Additional substance description:
sempervirine, (- )-31-acetyl-cyclomicrophylline-A, ( -)-benzoylbuxidienine, (+)-buxamine-C, (+ )-buxabenzamidienine
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Steroidal alkaloids (sempervirine, (- )-31-acetyl-cyclomicrophylline-A, ( -)-benzoylbuxidienine, (+)-buxamine-C, (+ )-buxabenzamidienine) in leaves
Composition #18: AttaurRahman., Choudhary, MI., Naz, S., Ata, A., Sener, B., Turkoz, S. New steroidal alkaloids from the roots of Buxus sempervirens. journal of natural products, 1997, vol. 60, no. 8, p. 770–774. DOI: 10.1021/np970028x.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
EtOH
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Substance:
Steroidal alkaloids (RF-00004336-PAR)
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Additional substance description:
Steroidal Alkamines
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Analytical method - additional description:
HS-MS, fractionation
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Steroidal alkamines
Composition #19: AttaurRahman., Choudhary, MI., Naz, S., Ata, A., Sener, B., Turkoz, S. New steroidal alkaloids from the roots of Buxus sempervirens. journal of natural products, 1997, vol. 60, no. 8, p. 770–774. DOI: 10.1021/np970028x.
[
DOI link]
-
-
Plant part:
Roots and other underground parts (as part-nature) (A067M)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
EtOH
-
Substance:
Steroidal alkaloids (RF-00004336-PAR)
-
Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
-
Analytical method - additional description:
HS-MS, fractionation
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
Steroidal alkaloids