Endpoint study
#1: Basch, Ethan., Boon, Heather., Davies-Heerema, Theresa., Foppo, Ivo., Hashmi, Sadaf., Hasskarl, Jens., Sollars, David., Ulbricht, Catherine. Boswellia: An evidence-based systematic review by the Natural Standard Research Collaboration . journal of herbal pharmacotherapy, 2004, vol. 4, no. 3, p. 63–83. .
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Study relevance:
Human health
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Type of toxicological test:
reproduction toxicity (CHD009TT)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
REPRODUCTIVE (TOX05A)
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Target tissue:
urogenital: Uterus (TT052A)
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Effect description:
Reports in the Indian literature suggest that resin from boswellia may induce abortion
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Effect or parameter linked to the endpoint:
reproduction (CHD014BE)
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Internal remarks:
Reports in the Indian literature suggest that resin from boswellia
may induce abortion
Endpoint study
#2: Singh, Pooja., Chacko, K Mathai., Aggarwal, M L., Bhat, Binu., Khandal, R K., Sultana, Sarwat., Kuruvilla, Binu T. A-90 Day Gavage Safety Assessment of Boswellia serrata in Rats.. toxicology international, 2012, vol. 19, no. 3, p. 273–8. DOI: 10.4103/0971-6580.103668.
[
DOI link]
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Study relevance:
Human health
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Type of toxicological test:
subchronic (CHD013TT)
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Tested organism:
Rat (as animal) (A0CNV)
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Route of exposure:
ORAL: GAVAGE (OECD2231PL)
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
10
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Control groups used:
yes, concurrent vehicle
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Milligrams per kilogram body weight per day (G211A)
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Effect concentration:
1000
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Critical effect:
Other toxicities (TOX19A)
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Effect description:
body weight decreased
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Effect or parameter linked to the endpoint:
body weight (CHD005BE)
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Internal remarks:
body weight decreased in highest dosed group (90-day-study)
