EFSA Compendium of Botanicals

Draft - work in progress

Banisteriopsis caapi (Spruce ex Griseb.) Morton

Family:: Malpighiaceae
Approval state:: Approved
Number of articles retrieved:: 205
Number of processed references:: 4

Compositions

#1: beta-Carboline alkaloids - Tetrahydroharmol #2: Harmine, harmaline and tetrahydroharmine #3: beta-Carboline alkaloids (harmine, harmaline and tetrahydroharmine) #4: harmine in seeds #5: harmaline in seeds

Endpoint Studies

Genotoxicity

Composition #1: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. Tetrahydroharmol (HMDB29835). human metabolome database, 2012 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

carboline alkaloids (RF-00004384-PAR)
Additional substance description:

Tetrahydroharmol
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

beta-Carboline alkaloids - Tetrahydroharmol

Composition #2: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. Harmalol (HMDB29838). human metabolome database, 2012 . .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

harmine (RF-00003854-PAR)
Additional substance description:

harmine, harmaline and tetrahydroharmine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Harmine, harmaline and tetrahydroharmine

Composition #3: Gable, Robert S. Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids . addiction, 2007, vol. 102, no. 1, p. 24–34. DOI: 10.1111/j.1360-0443.2006.01652.x. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Additional extraction description:

unspecified
Substance:

carboline alkaloids (RF-00004384-PAR)
Additional substance description:

beta-Carboline alkaloids (harmine, harmaline and tetrahydroharmine)
Analytical method - additional description:

unspecified
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.05-1.95
Internal remarks:

beta-Carboline alkaloids (harmine, harmaline and tetrahydroharmine)

Composition #4: Stankovic, Dalibor., Mehmeti, Eda., Svorc, Lubomir., Kalcher, Kurt. New electrochemical method for the determination of beta-carboline alkaloids, harmalol and harmine, in human urine samples and in Banisteriopsis caapi . microchemical journal, 2015, vol. 118, p. 95–100. DOI: 10.1016/j.microc.2014.08.007. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

harmine (RF-00003854-PAR)
Analytical method code:

Electrochemical tests (voltammetry and polarography) (F014A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.06
Internal remarks:

harmine in seeds

Composition #5: Stankovic, Dalibor., Mehmeti, Eda., Svorc, Lubomir., Kalcher, Kurt. New electrochemical method for the determination of beta-carboline alkaloids, harmalol and harmine, in human urine samples and in Banisteriopsis caapi . microchemical journal, 2015, vol. 118, p. 95–100. DOI: 10.1016/j.microc.2014.08.007. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

harmaline (RF-00003851-PAR)
Analytical method code:

Electrochemical tests (voltammetry and polarography) (F014A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.03-0.83
Internal remarks:

harmaline in seeds