EFSA
ecomole
vscht
  2. Aspidosperma quebracho-blanco Schltdl.

Aspidosperma quebracho-blanco Schltdl.

Family:
Apocynaceae
Approval state:
Approved
Number of articles retrieved:
186
Number of processed references:
16
Compositions
#1: Tannins in heartwood #2: Tannins in leaves #3: Aspidospermine in bark #4: Quebrachamine in bark #5: alkaloids in bark #6: yohimbine #7: Quebrachamine #8: 14,19-Didehydrocondyfolan #9: N-Methylaspidospermatidine #10: Aspidospermatine #11: 14,19-Dihydroaspidospermatine #12: (+)-Aspidospermidine #13: Aspidospermine #14: (+)-Quebrachidine #15: eburnamenine in bark #16: yohimbine in bark #17: aspidospermine in bark #18: quebrachamine in bark #19: aspidospermatin in bark #20: aspidospermatidine in bark #21: pyrifolidine, 12-methoxyaspidospermatidine in bark #22: aspidospermine in leaves #23: alkaloids in leaves #24: quebrachidine in leaves
Endpoint Studies
#1: mild analgesic activity
Genotoxicity
Composition #1: Prado, Luis L., Ricci, Enzo. Systematic study of the tannin content of various indigenous species. anales admin. nacl. bosques, rep. arg., 1956, p. 7–17. .
Composition #2: Prado, Luis L., Ricci, Enzo. Systematic study of the tannin content of various indigenous species. anales admin. nacl. bosques, rep. arg., 1956, p. 7–17. .
Composition #3: Biemann, K., Spiteller, G. Application of mass spectrometry to structure problems. VIII. Quebrachamine. journal of the american chemical society, 1962, vol. 84, p. 4578–86. .
Composition #4: Biemann, K., Spiteller, G. Application of mass spectrometry to structure problems. VIII. Quebrachamine. journal of the american chemical society, 1962, vol. 84, p. 4578–86. .
Composition #5: Markey, S., Biemann, Klaus., Witkop, Bernhard. Isolation of rhazidine and akuammidine from Aspidosperma quebracho-blanco. Structure of rhazidine. tetrahedron letters, 1967, vol. (2), p. 157–60. .
Composition #6: Wilson, E., Palacios, P., Rondina, R. V. D., Coussio, J. D. Determination of yohimbine in bark isolated from Aspidosperma quebracho blanco Schlecht. revista farmaceutica (buenos aires), 1983, vol. 125(1-4), p. 9–11. .
Composition #7: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (-)-Quebrachamine (HMDB30260). human metabolome database, 2012 . .
Composition #8: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. 14,19-Didehydrocondyfolan (HMDB30356). human metabolome database, 2012 . .
Composition #9: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. N-Methylaspidospermatidine (HMDB30357). human metabolome database, 2012 . .
Composition #10: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. Aspidospermatine (HMDB30358). human metabolome database, 2012 . .
Composition #11: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. 14,19-Dihydroaspidospermatine (HMDB30359). human metabolome database, 2012 . .
Composition #12: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (+)-Aspidospermidine (HMDB30360). human metabolome database, 2012 . .
Composition #13: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (-)-Aspidospermine (HMDB30361). human metabolome database, 2012 . .
Composition #14: Wishart, DS., Jewison, T., Guo, AC., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., Bouatra, S., Sinelnikov, I., Arndt, D., Xia, J., Liu, P., Yallou, F., Bjorndahl, T., Perez-Pineiro, R., Eisner, R., Allen, F., Neveu, V., Greiner, R., Scalbert, A. (+)-Quebrachidine (HMDB30390). human metabolome database, 2012 . .
Composition #15: Schnoes, H.K., Burlingame, A.L., Biemann, K. Application of mass spectrometry to structure problems: the occurrence of eburnamenine and related alkaloids in Rhazya stricta and Aspidosperma quebracho blanco. tetrahedron letters, 1962, vol. 3, no. 22, p. 993–999. .
Composition #16: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #17: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #18: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #19: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #20: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #21: BIEMANN, K., SPITELLER, G., SPITELLERFRIEDMANN, M. APPLICATION OF MASS SPECTROMETRY TO STRUCTURE PROBLEMS .10. ALKALOIDS OF BARK OF ASPIDOSPERMA QUEBRACHO BLANCO . journal of the american chemical society, 1963, vol. 85, no. 5, p. 631–&. DOI: 10.1021/ja00888a034. [DOI link]
Composition #22: LYON, RL., FONG, HHS., FARNSWORTH, NR., SVOBODA, GH. BIOLOGICAL AND PHYTOCHEMICAL EVALUATION OF PLANTS .9. ISOLATION OF ASPIDOSPERMINE, QUEBRACHIDINE, RHAZINILAM, (-)-PYRIFOLIDINE, AND AKUAMMIDINE FROM ASPIDOSPERMA-QUEBRACHO-BLANCO (APOCYNACEAE) . journal of pharmaceutical sciences, 1973, vol. 62, no. 2, p. 218–221. DOI: 10.1002/jps.2600620206. [DOI link]
Composition #23: LYON, RL., FONG, HHS., FARNSWORTH, NR., SVOBODA, GH. BIOLOGICAL AND PHYTOCHEMICAL EVALUATION OF PLANTS .9. ISOLATION OF ASPIDOSPERMINE, QUEBRACHIDINE, RHAZINILAM, (-)-PYRIFOLIDINE, AND AKUAMMIDINE FROM ASPIDOSPERMA-QUEBRACHO-BLANCO (APOCYNACEAE) . journal of pharmaceutical sciences, 1973, vol. 62, no. 2, p. 218–221. DOI: 10.1002/jps.2600620206. [DOI link]
Composition #24: LYON, RL., FONG, HHS., FARNSWORTH, NR., SVOBODA, GH. BIOLOGICAL AND PHYTOCHEMICAL EVALUATION OF PLANTS .9. ISOLATION OF ASPIDOSPERMINE, QUEBRACHIDINE, RHAZINILAM, (-)-PYRIFOLIDINE, AND AKUAMMIDINE FROM ASPIDOSPERMA-QUEBRACHO-BLANCO (APOCYNACEAE) . journal of pharmaceutical sciences, 1973, vol. 62, no. 2, p. 218–221. DOI: 10.1002/jps.2600620206. [DOI link]
Endpoint study #1: BENOIT, PS., ANGRY, G., LYON, RL., FONG, HHS., FARNSWORTH, NR. BIOLOGICAL AND PHYTOCHEMICAL EVALUATION OF PLANTS .13. PRELIMINARY ESTIMATION OF ANALGESIC ACTIVITY OF RHAZINILAM, A NOVEL ALKALOID ISOLATED FROM ASPIDOSPERMA-QUEBRACHO-BLANCO LEAVES . journal of pharmaceutical sciences, 1973, vol. 62, no. 11, p. 1889–1889. DOI: 10.1002/jps.2600621138. [DOI link]