EFSA
ecomole
vscht
  2. Roman wormwood (as plant) // Artemisia pontica L.

Roman wormwood (as plant) // Artemisia pontica L.

Family:
Asteraceae
Approval state:
Approved
Number of articles retrieved:
55
Number of processed references:
13
Compositions
#1: alpha-Thujone #2: 1,8-Cineole #3: Extragole #4: Pinocarvone #5: Camphor #6: 1,8-Cineole #7: Camphor #8: 1,8-cineole #9: 1,8-cineole #10: camphor in aerial parts, gc-ms #11: cineol, aerial parts, gc-ms #12: alfa-thujone, aerial parts, gc-ms #13: beta-thujone, aerial parts, gc-ms #14: camphor, aerial parts, gc-ms #15: piperitone epoxide, aerial parts, gc-ms #16: dihydroridentine in aerial parts, nmr #17: Alpha-Thujone #18: 1,8-Cineole #19: Artemisia ketone #20: isofraxidin sequiterpene ethers, drimartol A in roots, nmr #21: Santonin #22: alpha-terthienyl #23: sequiterpene lactone (rotundopontilides) in aerial parts, nmr #24: artemin, 5-epi-artemin
Endpoint Studies
#1: reduction in the body weight and hystopathologic damage of the liver only in males at 600 mg/kg; at the highest dose 2400 mg /kg showed a 50% of mortality in both sexes plus case reports in humans in the annex #2: Disturbances of vision in human (0.2 gr- yellow vision; 0.5 gr - green vision)
Genotoxicity
Composition #1: Nano, Gian M., Martelli, Aldo., Sancin, Peter. Chemical investigations of Artemisia grown in Piedmont. rivista italiana essenze, profumi, piante officinali, aromi, saponi, cosmetici, aerosol, 1966, vol. 98, no. 7, p. 409–12. .
Composition #2: Nano, Gian M., Martelli, Aldo., Sancin, Peter. Chemical investigations of Artemisia grown in Piedmont. rivista italiana essenze, profumi, piante officinali, aromi, saponi, cosmetici, aerosol, 1966, vol. 98, no. 7, p. 409–12. .
Composition #3: Nano, Gian M., Martelli, Aldo., Sancin, Peter. Chemical investigations of Artemisia grown in Piedmont. rivista italiana essenze, profumi, piante officinali, aromi, saponi, cosmetici, aerosol, 1966, vol. 98, no. 7, p. 409–12. .
Composition #4: Khanina, M. A., Serykh, E. A., Korolyuk, A. Yu., Bel'chenko, L. A., Pokrovsky, L. M., Tkachev, A. V. Composition of essential oil of Siberian populations of Artemisia pontica L. - as a promising medicinal plant. khimiya rastitel'nogo syr'ya, 2000, vol. (3), p. 85–94. .
Composition #5: Khanina, M. A., Serykh, E. A., Korolyuk, A. Yu., Bel'chenko, L. A., Pokrovsky, L. M., Tkachev, A. V. Composition of essential oil of Siberian populations of Artemisia pontica L. - as a promising medicinal plant. khimiya rastitel'nogo syr'ya, 2000, vol. (3), p. 85–94. .
Composition #6: Khanina, M. A., Serykh, E. A., Korolyuk, A. Yu., Bel'chenko, L. A., Pokrovsky, L. M., Tkachev, A. V. Composition of essential oil of Siberian populations of Artemisia pontica L. - as a promising medicinal plant. khimiya rastitel'nogo syr'ya, 2000, vol. (3), p. 85–94. .
Composition #7: Makarova, D. L., Khanina, M. A., Amel'chenko, V. P., Domrachev, D. V., Tkachev, A. V. Chemical study of essential oil of Artemisia pontica L. from Siberia. khimiya rastitel'nogo syr'ya, 2008, vol. (2), p. 55–60. .
Composition #8: Makarova, D. L., Khanina, M. A., Amel'chenko, V. P., Domrachev, D. V., Tkachev, A. V. Chemical study of essential oil of Artemisia pontica L. from Siberia. khimiya rastitel'nogo syr'ya, 2008, vol. (2), p. 55–60. .
Composition #9: De Vincenzi, M., Silano, M., De Vincenzi, A., Maialetti, F., Scazzocchio, B. Constituents of aromatic plants: eucalyptol. fitoterapia, 2002, vol. 73, no. 3, p. 269–275. DOI: 10.1016/S0367-326X(02)00062-X. [DOI link]
Composition #10: Bos, R., Stojanova, AS., Woerdenbag, HJ., Koulman, A., Quax, WJ. Volatile components of the aerial parts of Artemisia pontica L. grown in Bulgaria . flavour and fragrance journal, 2005, vol. 20, no. 2, p. 145–148. DOI: 10.1002/ffj.1399. [DOI link]
Composition #11: Bos, R., Stojanova, AS., Woerdenbag, HJ., Koulman, A., Quax, WJ. Volatile components of the aerial parts of Artemisia pontica L. grown in Bulgaria . flavour and fragrance journal, 2005, vol. 20, no. 2, p. 145–148. DOI: 10.1002/ffj.1399. [DOI link]
Composition #12: Talzhanov, NA., Sadyrbekov, DT., Smagulova, FM., Mukanov, RM., Raldugin, VA., Shakirov, MM., Tkachev, AV., Atazhanova, GA., Tuleuov, BI., Adekenov, SM. Components OF Artemisia pontica. chemistry of natural compounds, 2005, vol. 41, no. 2, p. 178–181. DOI: 10.1007/s10600-005-0107-x. [DOI link]
Composition #13: Talzhanov, NA., Sadyrbekov, DT., Smagulova, FM., Mukanov, RM., Raldugin, VA., Shakirov, MM., Tkachev, AV., Atazhanova, GA., Tuleuov, BI., Adekenov, SM. Components OF Artemisia pontica. chemistry of natural compounds, 2005, vol. 41, no. 2, p. 178–181. DOI: 10.1007/s10600-005-0107-x. [DOI link]
Composition #14: Talzhanov, NA., Sadyrbekov, DT., Smagulova, FM., Mukanov, RM., Raldugin, VA., Shakirov, MM., Tkachev, AV., Atazhanova, GA., Tuleuov, BI., Adekenov, SM. Components OF Artemisia pontica. chemistry of natural compounds, 2005, vol. 41, no. 2, p. 178–181. DOI: 10.1007/s10600-005-0107-x. [DOI link]
Composition #15: Talzhanov, NA., Sadyrbekov, DT., Smagulova, FM., Mukanov, RM., Raldugin, VA., Shakirov, MM., Tkachev, AV., Atazhanova, GA., Tuleuov, BI., Adekenov, SM. Components OF Artemisia pontica. chemistry of natural compounds, 2005, vol. 41, no. 2, p. 178–181. DOI: 10.1007/s10600-005-0107-x. [DOI link]
Composition #16: Talzhanov, NA., Mukanov, RM., Raldugin, VA., Shakirov, MM., Atazhanova, GA., Adekenov, SM. Dihydroridentin from Artemisia pontica and its stereochemistry. chemistry of natural compounds, 2005, vol. 41, no. 4, p. 423–425. DOI: 10.1007/s10600-005-0168-x. [DOI link]
Composition #17: HURABIELLE, M., TILLEQUIN, F., PARIS, M. CHEMICAL STUDY OF ARTEMISIA-PONTICA ESSENTIAL OIL. planta medica, 1977, vol. 31, no. 2, p. 97–102. .
Composition #18: HURABIELLE, M., TILLEQUIN, F., PARIS, M. CHEMICAL STUDY OF ARTEMISIA-PONTICA ESSENTIAL OIL. planta medica, 1977, vol. 31, no. 2, p. 97–102. .
Composition #19: HURABIELLE, M., TILLEQUIN, F., PARIS, M. CHEMICAL STUDY OF ARTEMISIA-PONTICA ESSENTIAL OIL. planta medica, 1977, vol. 31, no. 2, p. 97–102. .
Composition #20: GREGER, H., HOFER, O., NIKIFOROV, A. NEW SESQUITERPENE-COUMARIN ETHERS FROM ACHILLEA AND ARTEMISIA SPECIES. journal of natural products, 1982, vol. 45, no. 4, p. 455–461. DOI: 10.1021/np50022a017. [DOI link]
Composition #21: ARNOLD, WN., DALTON, TP., LOFTUS, LS., CONAN, PA. A SEARCH FOR SANTONIN IN ARTEMISIA-PONTICA, THE OTHER WORMWOOD OF OLD ABSINTHE . journal of chemical education, 1991, vol. 68, no. 1, p. 27–28. .
Composition #22: TOSI, B., BONORA, A., DALLOLIO, G., BRUNI, A. SCREENING FOR TOXIC THIOPHENE COMPOUNDS FROM CRUDE DRUGS OF THE FAMILY COMPOSITAE USED IN NORTHERN ITALY . phytotherapy research, 1991, vol. 5, no. 2, p. 59–62. DOI: 10.1002/ptr.2650050204. [DOI link]
Composition #23: Todorova, MN., Tsankova, ET., Trendafilova, AB., Gussev, CV. Sesquiterpene lactones with the uncommon rotundane skeleton from Artemisia pontica L. . phytochemistry, 1996, vol. 41, no. 2, p. 553–556. DOI: 10.1016/0031-9422(95)00640-0. [DOI link]
Composition #24: Trendafilova, AB., Todorova, MN., Gussev, CV. Eudesmanolides from Artemisia pontica. phytochemistry, 1996, vol. 42, no. 2, p. 469–471. DOI: 10.1016/0031-9422(95)00941-8. [DOI link]
Endpoint study #1: De Vincenzi, M., Silano, M., De Vincenzi, A., Maialetti, F., Scazzocchio, B. Constituents of aromatic plants: eucalyptol. fitoterapia, 2002, vol. 73, no. 3, p. 269–275. DOI: 10.1016/S0367-326X(02)00062-X. [DOI link]
Endpoint study #2: ARNOLD, WN., DALTON, TP., LOFTUS, LS., CONAN, PA. A SEARCH FOR SANTONIN IN ARTEMISIA-PONTICA, THE OTHER WORMWOOD OF OLD ABSINTHE . journal of chemical education, 1991, vol. 68, no. 1, p. 27–28. .