EFSA Compendium of Botanicals

Draft - work in progress

Artemisia pallens DC.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 159
Number of processed references:: 6

Compositions

#1: Artemisinin in unspecified parts #2: Saponins in aerial parts #3: santonin in plant material #4: eudesmanolides in aerial parts #5: furan derivatives in unspecified part #6: Germacranolide in aerial parts

Endpoint Studies

Genotoxicity

Composition #1: Suresh, J., Mruthunjaya, K., Paramakrishnan, N., Naganandhini, M. N. Determination of Artemisinin in Artemisia abrotanum and Artemisia pallens by LC/MS method. international journal of current pharmaceutical research, 2011, vol. 3, no. 1, p. 49–52. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

artemisinin (RF-00003658-PAR)
Analytical method code:

LC-MS (F026A)
Analytical method - additional description:

RP‐LC/MS method
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.103
Internal remarks:

Artemisinin in unspecified parts

Composition #2: Kumar, A.P., Kumud, U. Pharmacognostic and phytochemical investigation of aerial parts of Artemisia pallens Wall ex.Dc. pharmacognosy journal, 2010, vol. 2, no. 9, p. 285–288. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol / Chloroform water
Substance:

Saponins (RF-00004333-PAR)
Analytical method code:

Phytochemical screening (F604A)
Analytical method - additional description:

Foam test
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in aerial parts

Composition #3: Ruikar, A., Jadhav, R., Tambe, A., Misar, A., Mujumdar, A., Puranik, V., Deshpande, N. Quantification of santonin from Artemisia pallens wall by HPTLC. international journal of pharma and bio sciences, 2010, vol. 1, no. 1 . .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone / methanol (dried plant material)
Substance:

santonin (RF-00003572-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.94 - 40.71
Internal remarks:

santonin in plant material

Composition #4: Ruikar, Anjali D., Jadhav, Ravindra B., Phalgune, Usha D., Rojatkar, Supada R., Puranik, Vedavati G., Deshpande, Nirmala R. Phytochemical Investigation of Artemisia pallens. helvetica chimica acta, 2011, vol. 94, no. 1, p. 73–77. DOI: 10.1002/hlca.201000125. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

acetone
Substance:

sesquiterpene lactones type eudesmanolide sesquiterpene lactones type eudesmanolide (RF-00004395-PAR)
Additional substance description:

pallensin, 4-epipallensin, santonin
Analytical method code:

Chromatographic tests (F015A)
Analytical method - additional description:

TLC analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

eudesmanolides in aerial parts

Composition #5: MISRA, LN., CHANDRA, A., THAKUR, RS. FRAGRANT COMPONENTS OF OIL FROM ARTEMISIA-PALLENS. phytochemistry, 1991, vol. 30, no. 2, p. 549–552. DOI: 10.1016/0031-9422(91)83725-Z. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

furan derivatives (RF-00004396-PAR)
Additional substance description:

alpha and beta-Dihydrorosefuran, davanone and derivatives, artemone, Furano-nor-diterpenoid, Furano-sesquiterpene alcohol
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

furan derivatives in unspecified part

Composition #6: Rojatkar, SR., Pawar, SS., Pujar, PP., Sawaikar, DD., Gurunath, S., Sathe, VT., Nagasampagi, BA. A germacranolide from Artemisia pallens. phytochemistry, 1996, vol. 41, no. 4, p. 1105–1106. DOI: 10.1016/0031-9422(95)00772-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Acetone extract
Substance:

Germacranolide (RF-00011355-PAR)
Additional substance description:

4,5 fl-epoxy- 10~-hydroxy- 1-en-3-one-trans-germacran-6u, 12-olide
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Analytical method - additional description:

repeated column chromatography coupled with preparative TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Germacranolide in aerial parts