EFSA
ecomole
vscht
  2. Aristolochia contorta Bunge

Aristolochia contorta Bunge

Family:
Aristolochiaceae
Approval state:
Approved
Number of articles retrieved:
151
Number of processed references:
7
Compositions
#1: aporphine alkaloids in roots #2: Aristolactam I. #3: Aristolochic acid I. #4: Aristolochic acids in fruits #5: aristolic acid in whole plant #6: aristolactam and derivatives in stem and leaves #7: aristolochic acids and derivatives in stem and leaves #8: esculetin in stem and leaves #9: p-coumaric acid in stem and leaves #10: total aristolochic acids #11: aristolactams #12: magnocurarine in seeds #13: magnoflorine in seeds
Endpoint Studies
#1: acute toxicity #2: sub acute nephrotoxicity
Genotoxicity
Composition #1: Lee, Heum Sook., Han, Dae Suk., Won, Dug Kwon. Studies on the constituents of the root of Aristolochia contorta. (II). Oxoaporphines. saengyak hakhoechi, 1990, vol. 21, no. 1, p. 52–5. .
Composition #2: Hu, Yong., Wu, Hai-Long., Yin, Xiao-Li., Gu, Hui-Wen., Xiao, Rong., Wang, Li., Fang, Huan., Yu, Ru-Qin. Interference-free spectrofluorometric quantification of aristolochic acid I and aristololactam I in five Chinese herbal medicines using chemical derivatization enhancement and second-order calibration methods. spectrochimica acta, part a: molecular and biomolecular spectroscopy, 2017, vol. 175, p. 229–238. .
Composition #3: Hu, Yong., Wu, Hai-Long., Yin, Xiao-Li., Gu, Hui-Wen., Xiao, Rong., Wang, Li., Fang, Huan., Yu, Ru-Qin. Interference-free spectrofluorometric quantification of aristolochic acid I and aristololactam I in five Chinese herbal medicines using chemical derivatization enhancement and second-order calibration methods. spectrochimica acta, part a: molecular and biomolecular spectroscopy, 2017, vol. 175, p. 229–238. .
Composition #4: Yuan, J.-B., Huang, Q., Ren, G., Shi, M., Chen, L., Yang, W.-L., Chen, H.-F., Yang, M., Yang, B., Yang, G.-H., Luo, X.-Q. Acute and subacute toxicity of the extract of Aristolochiae Fructus and honey-fried Aristolochiae Fructus in rodents. biological and pharmaceutical bulletin, 2014, vol. 37, no. 3, p. 387–393. DOI: 10.1248/bpb.b13-00736. [DOI link]
Composition #5: Wei, F., Cheng, XL., Ma, LY., Jin, WT., Schaneberg, BT., Khan, IA., Lin, RC. Analysis of aristolochic acids and analogues in medicinal plants and their commercial products by HPLC-PAD-ESI/MS . phytochemical analysis, 2005, vol. 16, no. 3, p. 222–230. DOI: 10.1002/pca.849. [DOI link]
Composition #6: Zhang, CY., Wang, X., Su, T., Ma, CM., Wen, YJ., Shang, MY., Li, XM., Liu, GX., Cai, SQ. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta . pharmazie, 2005, vol. 60, no. 10, p. 785–788. .
Composition #7: Zhang, CY., Wang, X., Su, T., Ma, CM., Wen, YJ., Shang, MY., Li, XM., Liu, GX., Cai, SQ. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta . pharmazie, 2005, vol. 60, no. 10, p. 785–788. .
Composition #8: Zhang, CY., Wang, X., Su, T., Ma, CM., Wen, YJ., Shang, MY., Li, XM., Liu, GX., Cai, SQ. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta . pharmazie, 2005, vol. 60, no. 10, p. 785–788. .
Composition #9: Zhang, CY., Wang, X., Su, T., Ma, CM., Wen, YJ., Shang, MY., Li, XM., Liu, GX., Cai, SQ. New aristolochic acid, aristololactam and renal cytotoxic constituents from the stem and leaves of Aristolochia contorta . pharmazie, 2005, vol. 60, no. 10, p. 785–788. .
Composition #10: Yuan, Jinbin., Liu, Qian., Zhu, Weifeng., Ding, Li., Tang, Fei., Yao, Shouzhuo. Simultaneous analysis of six aristolochic acids and five aristolactams in herbal plants and their preparations by high-performance liquid chromatography-diode array detection-fluorescence detection . journal of chromatography a, 2008, vol. 1182, no. 1, p. 85–92. DOI: 10.1016/j.chroma.2007.12.076. [DOI link]
Composition #11: Yuan, Jinbin., Liu, Qian., Zhu, Weifeng., Ding, Li., Tang, Fei., Yao, Shouzhuo. Simultaneous analysis of six aristolochic acids and five aristolactams in herbal plants and their preparations by high-performance liquid chromatography-diode array detection-fluorescence detection . journal of chromatography a, 2008, vol. 1182, no. 1, p. 85–92. DOI: 10.1016/j.chroma.2007.12.076. [DOI link]
Composition #12: Mao Wen-Wen., Gao Wen., Liang Zhi-Tao., Li Ping., Zhao Zhong-Zhen., Li Hui-Jun. Characterization and quantitation of aristolochic acid analogs in different parts of Aristolochiae Fructus, using UHPLCQ/TOF-MS and UHPLC-QqQ-MS . chinese journal of natural medicines, 2017, vol. 15, no. 5, p. 392–400. .
Composition #13: Mao Wen-Wen., Gao Wen., Liang Zhi-Tao., Li Ping., Zhao Zhong-Zhen., Li Hui-Jun. Characterization and quantitation of aristolochic acid analogs in different parts of Aristolochiae Fructus, using UHPLCQ/TOF-MS and UHPLC-QqQ-MS . chinese journal of natural medicines, 2017, vol. 15, no. 5, p. 392–400. .
Endpoint study #1: Yuan, J.-B., Huang, Q., Ren, G., Shi, M., Chen, L., Yang, W.-L., Chen, H.-F., Yang, M., Yang, B., Yang, G.-H., Luo, X.-Q. Acute and subacute toxicity of the extract of Aristolochiae Fructus and honey-fried Aristolochiae Fructus in rodents. biological and pharmaceutical bulletin, 2014, vol. 37, no. 3, p. 387–393. DOI: 10.1248/bpb.b13-00736. [DOI link]
Endpoint study #2: Yuan, J.-B., Huang, Q., Ren, G., Shi, M., Chen, L., Yang, W.-L., Chen, H.-F., Yang, M., Yang, B., Yang, G.-H., Luo, X.-Q. Acute and subacute toxicity of the extract of Aristolochiae Fructus and honey-fried Aristolochiae Fructus in rodents. biological and pharmaceutical bulletin, 2014, vol. 37, no. 3, p. 387–393. DOI: 10.1248/bpb.b13-00736. [DOI link]