EFSA Compendium of Botanicals

Draft - work in progress

Apocynum androsaemifolium L.

Family:: Apocynaceae
Approval state:: Approved
Number of articles retrieved:: 96
Number of processed references:: 1

Compositions

#1: apocannoside in roots #2: cardenolide glucosides in roots #3: apobioside in roots #4: cymarin in roots #5: k-strophantin-beta in roots

Endpoint Studies

Genotoxicity

Composition #1: Genkina, G. L., Khodzhaev, K. Kh., Shakirov, T. T., Abubakirov, N. K. Roots of Apocynum androsaemifolium and Apocynum cannabinum studied for cardenolide content. khimiya prirodnykh soedinenii, 1972, vol. (3), p. 321–4. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

apocannoside
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

phototcolorimetric determination,
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.045-0.048
Internal remarks:

apocannoside in roots

Composition #2: Genkina, G. L., Khodzhaev, K. Kh., Shakirov, T. T., Abubakirov, N. K. Roots of Apocynum androsaemifolium and Apocynum cannabinum studied for cardenolide content. khimiya prirodnykh soedinenii, 1972, vol. (3), p. 321–4. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

cardenolide glycosides cardenolide glycosides (RF-00004348-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

phototcolorimetric determination,
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.056-0.537
Internal remarks:

cardenolide glucosides in roots

Composition #3: Genkina, G. L., Khodzhaev, K. Kh., Shakirov, T. T., Abubakirov, N. K. Roots of Apocynum androsaemifolium and Apocynum cannabinum studied for cardenolide content. khimiya prirodnykh soedinenii, 1972, vol. (3), p. 321–4. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

apobioside
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

phototcolorimetric determination,
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.027-0.122
Internal remarks:

apobioside in roots

Composition #4: Genkina, G. L., Khodzhaev, K. Kh., Shakirov, T. T., Abubakirov, N. K. Roots of Apocynum androsaemifolium and Apocynum cannabinum studied for cardenolide content. khimiya prirodnykh soedinenii, 1972, vol. (3), p. 321–4. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

cymarin (RF-00003761-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

phototcolorimetric determination,
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.007-0.19
Internal remarks:

cymarin in roots

Composition #5: Genkina, G. L., Khodzhaev, K. Kh., Shakirov, T. T., Abubakirov, N. K. Roots of Apocynum androsaemifolium and Apocynum cannabinum studied for cardenolide content. khimiya prirodnykh soedinenii, 1972, vol. (3), p. 321–4. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol 70%
Substance:

cardenolides (RF-00004389-PAR)
Additional substance description:

k-strophantin-beta
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

phototcolorimetric determination,
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.026-0.25
Internal remarks:

k-strophantin-beta in roots