EFSA Compendium of Botanicals

Draft - work in progress

Anticlea sibirica (L.) Kunth // Zigadenus sibiricus (L.) A.Gray.

Family:: Melanthiaceae
Approval state:: Approved
Number of articles retrieved:: 4
Number of processed references:: 2

Compositions

#1: Veratrine #2: Triterpene alkaloids (verazine, veratroylzygadenine, verazinine)

Endpoint Studies

Genotoxicity

Composition #1: Varlakov, M. N. Substitutes for imported veratrine. farmatsiya (moscow, 1938-47), 1941, vol. (No. 1), p. 27–9. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Additional extraction description:

unspecified
Substance:

cevadine (RF-00004200-PAR)
Additional substance description:

veratrine (syn.)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Veratrine

Composition #2: Taskhanova, E. M., Shakirov, R., Yunusov, S. Yu. Alkaloids from Zygadenus sibiricus. Structure of verazinine. khimiya prirodnykh soedinenii, 1985, vol. (3), p. 368–9. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

verazine, veratroylzygadenine, verazinine
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Triterpene alkaloids (verazine, veratroylzygadenine, verazinine)