EFSA Compendium of Botanicals

Draft - work in progress

Anthriscus sylvestris (L.) Hoffm.

Family:: Apiaceae
Approval state:: Approved
Number of articles retrieved:: 493
Number of processed references:: 9

Compositions

#1: sissotrin in leaves #2: daidzin in leaves #3: genistin in leaves #4: 6,7,4´- trihydroxyisoflavone in leaves #5: isoformononetin in leaves #6: daidzein in leaves #7: formononetin in leaves #8: arctigenin in rhizomes #9: phylligenin in rhizomes #10: myrcene (17%) in leaves #11: benzene acetaldehyde (4.1%) in leaves #12: secoilariciresinol in aerial parts #13: lariciresinol in aerial parts #14: matairesinol in aerial parts #15: hinokinin in aerial parts #16: pluviatolide in aerial parts #17: yatein in aerial parts #18: anhydropodorhizol in roots #19: deoxypodophyllotoxin in roots #20: morelensin in roots #21: hinokinin in roots #22: bursehernin in roots #23: angeloylpodophyllotoxin in roots #24: yatein in roots #25: scopoletin in roots #26: 5-methoxypsoralen in roots #27: deoxypodophyllotoxin in roots #28: deoxypodorhizone in roots #29: sylvestrin, nemerosin, angeloyl podophyllotoxin, deoxypicropodophyllotoxin in roots #30: picropodophyllotoxin in roots #31: isoscopoletin in roots #32: falcarindiol in roots #33: hibalactone in roots #34: podophyllotoxone, beta-peltatin-a-methylether, 2-Angeloyloxymethyl-2- butenoic acid, anthriscinol methyl ether, anthriscrusin in roots #35: alpha-peltatin in roots #36: beta-peltatin in roots #37: podophyllotoxin in roots #38: myrcene (8.7-48.4%) in rhizomes

Endpoint Studies

Genotoxicity

Composition #1: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

Sissotrin (RF-00011021-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

sissotrin in leaves

Composition #2: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

daidzin (RF-00003763-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Result unit:

Milligram/kilogram (G061A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.4
Internal remarks:

daidzin in leaves

Composition #3: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

genistin (RF-00003829-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Result unit:

Milligram/kilogram (G061A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.8
Internal remarks:

genistin in leaves

Composition #4: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

Isoflavonoids Isoflavonoids (RF-00000439-NTR)
Additional substance description:

6,7,4´- trihydroxyisoflavone
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Result unit:

Milligram/kilogram (G061A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.0
Internal remarks:

6,7,4´- trihydroxyisoflavone in leaves

Composition #5: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

Isoformononetin (RF-00011018-PAR)
Additional substance description:

isofomononetin (spelling mistake in the text)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Result unit:

Milligram/kilogram (G061A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.5
Internal remarks:

isoformononetin in leaves

Composition #6: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

daidzein (RF-00000061-NTR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

daidzein in leaves

Composition #7: Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family. biochemical systematics and ecology, 2012, vol. 45, p. 237–243. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol 70%
Substance:

formononetin (RF-00000291-NTR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Analytical method - additional description:

HPLC-MS, Immunoaffinity chromatography, ELISA
Result expression:

Dry matter (B002A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

formononetin in leaves

Composition #8: Koulman, A., Bos, R., Medarde, M., Pras, N., Quax, WJ. A fast and simple GC MS method for lignan profiling in Anthriscus sylvestris and biosynthetically related plant species . planta medica, 2001, vol. 67, no. 9, p. 858–862. DOI: 10.1055/s-2001-18849. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol and cichonodin
Substance:

Arctigenin (RF-00011084-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

arctigenin in rhizomes

Composition #9: Koulman, A., Bos, R., Medarde, M., Pras, N., Quax, WJ. A fast and simple GC MS method for lignan profiling in Anthriscus sylvestris and biosynthetically related plant species . planta medica, 2001, vol. 67, no. 9, p. 858–862. DOI: 10.1055/s-2001-18849. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol and cichonodin
Substance:

phylligenin (RF-00011388-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

phylligenin in rhizomes

Composition #10: Bos, R., Koulman, A., Woerdenbag, HJ., Quax, WJ., Pras, N. Volatile components from Anthriscus sylvestris (L.) Hoffm.. journal of chromatography a, 2002, vol. 966, no. 1-2, p. 233–238. DOI: 10.1016/S0021-9673(02)00704-5. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.3-16.7
Internal remarks:

myrcene (17%) in leaves

Composition #11: Bos, R., Koulman, A., Woerdenbag, HJ., Quax, WJ., Pras, N. Volatile components from Anthriscus sylvestris (L.) Hoffm.. journal of chromatography a, 2002, vol. 966, no. 1-2, p. 233–238. DOI: 10.1016/S0021-9673(02)00704-5. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Phenylacetaldehyde (RF-00009234-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1-4.1
Internal remarks:

benzene acetaldehyde (4.1%) in leaves

Composition #12: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

secoisolarisiresinol (RF-00000390-NTR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

secoilariciresinol in aerial parts

Composition #13: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lariciresinol (RF-00011086-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

lariciresinol in aerial parts

Composition #14: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

matairesinol (RF-00000331-NTR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

matairesinol in aerial parts

Composition #15: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Hinokinin (RF-00011074-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hinokinin in aerial parts

Composition #16: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

pluviatolide
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pluviatolide in aerial parts

Composition #17: Suzuki, S., Sakakibara, N., Umezawa, T., Shimada, M. Survey and enzymatic formation of lignans of Anthriscus sylvestris. journal of wood science, 2002, vol. 48, no. 6, p. 536–541. DOI: 10.1007/BF00766653. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Yatein (RF-00011078-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

yatein in aerial parts

Composition #18: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

anhydropodorhizol
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.001-0.2
Internal remarks:

anhydropodorhizol in roots

Composition #19: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

deoxypodophyllotoxin (RF-00003769-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.2-1.7
Internal remarks:

deoxypodophyllotoxin in roots

Composition #20: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

morelensin
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.001-0.02
Internal remarks:

morelensin in roots

Composition #21: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

Hinokinin (RF-00011074-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.001-0.4
Internal remarks:

hinokinin in roots

Composition #22: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

Bursehernin (RF-00011073-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.001-0.1
Internal remarks:

bursehernin in roots

Composition #23: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

angeloylpodophyllotoxin
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.001-0.5
Internal remarks:

angeloylpodophyllotoxin in roots

Composition #24: Koulman, A., Kubbinga, ME., Batterman, S., Woerdenbag, HJ., Pras, N., Woolley, JG., Quax, WJ. A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris . planta medica, 2003, vol. 69, no. 8, p. 733–738. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

dichlormethane, methanol
Substance:

Yatein (RF-00011078-PAR)
Analytical method code:

HPLC-DAD (F587A)
Analytical method - additional description:

GC, GC/MS
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1-0.6
Internal remarks:

yatein in roots

Composition #25: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

scopoletin (RF-00004048-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

scopoletin in roots

Composition #26: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Bergapten (RF-00003837-PAR)
Additional substance description:

synonym for 5-methoxypsoralen
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

5-methoxypsoralen in roots

Composition #27: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

deoxypodophyllotoxin (RF-00003769-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

deoxypodophyllotoxin in roots

Composition #28: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Yatein (RF-00011078-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

deoxypodorhizone in roots

Composition #29: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

sylvestrin, nemerosin, angeloyl podophyllotoxin, deoxypicropodophyllotoxin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

sylvestrin, nemerosin, angeloyl podophyllotoxin, deoxypicropodophyllotoxin in roots

Composition #30: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

picropodophyllin (RF-00011091-PAR)
Additional substance description:

synonym for picropodophyllotoxin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

picropodophyllotoxin in roots

Composition #31: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Isoscopoletin (RF-00010985-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

isoscopoletin in roots

Composition #32: Jeong, Gil-Saeng., Kwon, Ok-Kyoung., Park, Bo-Young., Oh, Sei-Ryang., Ahn, Kyung-Seop., Chang, Min-Jung., Oh, Won Keun., Kim, Jin-Cheol., Min, Byung-Sun., Kim, Youn-Chul., Lee, Hyeong-Kyu. Lignans and coumarins from the roots of Anthriscus sylvestris and their increase of caspase-3 activity in HL-60 cells . biological & pharmaceutical bulletin, 2007, vol. 30, no. 7, p. 1340–1343. DOI: 10.1248/bpb.30.1340. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

falcarindiol (RF-00003811-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR, NMR, EI-MS,
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

falcarindiol in roots

Composition #33: Lim, Hye-Sun., Oh, Sei-Ryang., Lee, Ho-Jae., Chin, Young-Won., Ahn, Kyung-Seop., Sok, Dai-Eun., Lee, Hyeong-Kyu. Suppressive Effects of Anthriscus sylvestris Constituents on the Expression and Production of Matrix Metalloproteinase-9 Using Luciferase Transfected Raw 264.7 Cell Based Assay System . journal of the korean society for applied biological chemistry, 2009, vol. 52, no. 6, p. 620–625. DOI: 10.3839/jksabe.2009.103. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

hibalactone
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Analytical method - additional description:

NMR, HPLC, TLC, UV, HR-ESI
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

hibalactone in roots

Composition #34: Hendrawati, Oktavia., Woerdenbag, Herman J., Michiels, Paul J. A., Aantjes, Herald G., van Dam, Annie., Kayser, Oliver. Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR . phytochemistry, 2011, vol. 72, no. 17, p. 2172–2179. DOI: 10.1016/j.phytochem.2011.08.009. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 80%
Substance:

lignans (RF-00004361-PAR)
Additional substance description:

isopicropodophyllone, podophyllotoxone, beta-peltatin-a-methylether, 2-Angeloyloxymethyl-2- butenoic acid, anthriscinol methyl ether, anthriscrusin
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

LC-ESI-MS/MS, LC.SPE, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

podophyllotoxone, beta-peltatin-a-methylether, 2-Angeloyloxymethyl-2- butenoic acid, anthriscinol methyl ether, anthriscrusin in roots

Composition #35: Hendrawati, Oktavia., Woerdenbag, Herman J., Michiels, Paul J. A., Aantjes, Herald G., van Dam, Annie., Kayser, Oliver. Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR . phytochemistry, 2011, vol. 72, no. 17, p. 2172–2179. DOI: 10.1016/j.phytochem.2011.08.009. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 80%
Substance:

peltatin A (RF-00003983-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

LC-ESI-MS/MS, LC.SPE, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alpha-peltatin in roots

Composition #36: Hendrawati, Oktavia., Woerdenbag, Herman J., Michiels, Paul J. A., Aantjes, Herald G., van Dam, Annie., Kayser, Oliver. Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR . phytochemistry, 2011, vol. 72, no. 17, p. 2172–2179. DOI: 10.1016/j.phytochem.2011.08.009. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 80%
Substance:

beta-peltatin A (RF-00003711-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

LC-ESI-MS/MS, LC.SPE, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

beta-peltatin in roots

Composition #37: Hendrawati, Oktavia., Woerdenbag, Herman J., Michiels, Paul J. A., Aantjes, Herald G., van Dam, Annie., Kayser, Oliver. Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR . phytochemistry, 2011, vol. 72, no. 17, p. 2172–2179. DOI: 10.1016/j.phytochem.2011.08.009. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol 80%
Substance:

podophyllotoxin (RF-00004001-PAR)
Analytical method code:

HPLC-UV (F021A)
Analytical method - additional description:

LC-ESI-MS/MS, LC.SPE, NMR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

podophyllotoxin in roots

Composition #38: St-Gelais, Alexis., Caron, Laurie., Collin, Guy., Marceau, Hubert., Pichette, Andre. Aromas from Quebec. III. Composition of the essential oil and hydrolate of the roots of Anthriscus sylvestris (L.) Hoffm. from Saguenay . journal of essential oil research, 2015, vol. 27, no. 5, p. 373–379. DOI: 10.1080/10412905.2015.1060176. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (Q) (F344A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.7-48.4
Internal remarks:

myrcene (8.7-48.4%) in rhizomes