EFSA Compendium of Botanicals

Draft - work in progress

Anthemis cotula L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 179
Number of processed references:: 3

Compositions

#1: myrcene in aerial part #2: naphthalene in aerial part #3: Anthecotuloide and derivatives (sesquiterpene lactones) #4: Polyacetylene derivatives #5: myrcene

Endpoint Studies

Genotoxicity

Composition #1: Saroglou, V., Dorizas, N., Kypriotakis, Z., Skaltsa, HD. Analysis of the essential oil composition of eight Anthemis species from Greece . journal of chromatography a, 2006, vol. 1104, no. 1-2, p. 313–322. DOI: 10.1016/j.chroma.2005.11.087. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.4
Internal remarks:

myrcene in aerial part

Composition #2: Saroglou, V., Dorizas, N., Kypriotakis, Z., Skaltsa, HD. Analysis of the essential oil composition of eight Anthemis species from Greece . journal of chromatography a, 2006, vol. 1104, no. 1-2, p. 313–322. DOI: 10.1016/j.chroma.2005.11.087. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

Naphthalene (RF-0801-001-PPP)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.6
Internal remarks:

naphthalene in aerial part

Composition #3: Vuckovic, I., Vujisic, L., Vajs, V., Tesevic, V., Janackovic, P., Milosavljevic, S. Phytochemical investigation of Anthemis cotula. journal of the serbian chemical society, 2006, vol. 71, no. 2, p. 127–133. DOI: 10.2298/JSC0602127V. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleum Ether + Flash Chromatography
Substance:

Sesquiterpene lactones (RF-00004319-PAR)
Additional substance description:

Anthecotuloide and derivatives
Analytical method code:

Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy (F060A)
Analytical method - additional description:

Mass Spectrometry - Infrared spectroscopy
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Anthecotuloide and derivatives (sesquiterpene lactones)

Composition #4: Vuckovic, I., Vujisic, L., Vajs, V., Tesevic, V., Janackovic, P., Milosavljevic, S. Phytochemical investigation of Anthemis cotula. journal of the serbian chemical society, 2006, vol. 71, no. 2, p. 127–133. DOI: 10.2298/JSC0602127V. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleum Ether + Flash Chromatography
Substance:

polyacetylene derivatives polyacetylene derivatives (RF-00004332-PAR)
Analytical method code:

Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectroscopy (F060A)
Analytical method - additional description:

Mass Spectrometry - Infrared spectroscopy
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Polyacetylene derivatives

Composition #5: Pavlovic, Milica., Lakusic, Dmitar., Kovacevic, Nada., Tzakou, Olga., Couladis, Maria. Comparative Analysis of Essential Oils of Six Anthemis Taxa from Serbia and Montenegro . chemistry & biodiversity, 2010, vol. 7, no. 5, p. 1231–1244. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC retention indices
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=2.5
Internal remarks:

myrcene