EFSA
ecomole
vscht
  2. Custard apple (as plant) // Annona reticulata L.

Custard apple (as plant) // Annona reticulata L.

Family:
Annonaceae
Approval state:
Approved
Number of articles retrieved:
379
Number of processed references:
17
Compositions
#1: Anonaine in the bark #2: reticuline in the root bark #3: alkaloids: oxoushinsunine, annonaine, 3-​hydroxynornuciferine​, annomontine, methoxyannomontine from the stem bark #4: michelalbine from the roots #5: alkaloids: oxoushinsunine, annonaine, 3-​hydroxynornuciferine​, annomontine, methoxyannomontine from the roots #6: asimilobine​ from the roots #7: reticuline from the roots #8: asimilobine from the stem bark #9: reticuline from the stem bark #10: michelalbine from the stem bark #11: acetogenins ( acetogenins (polyketides)​: annonareticin (1)​, 2,​4-​cis-​isoannonareticin (2-​1)​, 2,​4-​trans-​isoannonareticin (2-​2)​, solamin (3)​, murisolin (4)​, reticulacinone (5)​, annoreticuin (6)​, annomonicin) in seeds #12: asimicin (= squamocin-​H)​, annonacin-​10-​one, squamostatin-​A , 10-​hydroxyasimicin (squamocin-​Z)​, annonacin​, murisolin​, bullatacin (= squamocin-​G) and squamocin in the fruits #13: asimilobine in the leaves #14: aporphine alkaloids (xylopine, norcorydine, oxoxylopine (lanuginosine)) in the leaves #15: oxonantenine in the leaves #16: corydine in the leaves #17: glaucine in the leaves #18: liriodenine (oxoushinsunine) in the leaves #19: acetogenins (2, 4-cis-squamone diacetate, 2, 4-trans-squamone diacetate, 2, 4-cis-isoannonareticin diacetate, 2,4-trans-isoannonareticin diacetate, 2, 4-cis-squamone, 2, 4-trans-isoannonareticin ) in the seeds #20: salsolinol (isoquinoline alkaloid) from the leaves #21: coclaurine from the leaves #22: coclaurine from the stems #23: salsolinol (isoquinoline alkaloid) from the stems #24: dopamine from the leaves #25: dopamine from the stems #26: reticuline in roots #27: neoanonin in roots #28: norushinsunine in roots #29: iriodenine in roots #30: Acetogenins (annoreticiun-9-one, bullatacin, squamocin) in seeds #31: myrcene in fruits #32: liriodenine in leaves and stems #33: liriodenine in roots #34: liriodenine in bark #35: reticulatacin, reticulatacin diacetate, bullatacin, adriamycin in bark #36: annonacins: annoreticuin and isoannoreticuin from the leaves #37: annoreticutin, isoannoretocutin, annoreticutin-9-one, squamone, solamin, annomonicin in leaves #38: Acetogenins (reticulatain-1, reticulatain-2, reticulatacin and uvariamicin III) in seeds #39: acetogenins (epomusenins A and B, squamocin, rolliniastatin-1 and -2) in fruits
Endpoint Studies
Genotoxicity
Composition #1: Santos, Alfredo C. Alkaloid from Anona Reticulata Linnaeus. philippine journal of science, 1930, vol. 43, p. 561–4. .
Composition #2: Gopinath, K. W., Govindachari, T. R., Pai, B. R., Viswanathan, N. The structure of reticuline, a new alkaloid from Anona reticulata. chemische berichte, 1959, vol. 92, p. 776–9. .
Composition #3: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #4: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #5: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #6: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #7: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #8: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #9: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #10: Yang, Tsang Hsiung., Cheng, Mu Ying. The alkaloids of Annona reticulata L. II. taiwan yaoxue zazhi, 1987, vol. 39, no. 3, p. 195–201. .
Composition #11: Liu, Dong., Yu, Jingguang., Sun, Lan., Luo, Xiuzhen., Guo, Shaorong., Lin, Jitian. Chemical constituents of the seeds from Annona reticulata (Annonaceae). tianran chanwu yanjiu yu kaifa, 1998, vol. 10, no. 2, p. 1–7. .
Composition #12: Araya, H., Maeda, U., Hara, N., Prasad, S., Begum, A. S., Sahai, M., Fujimoto, Y. Potent biologically active tetrahydrofuranic acetogenins from custard apple (Annona reticulate Linn) seeds. meiji daigaku nogakubu kenkyu hokoku, 2012, vol. 62, no. 1, p. 1–9. .
Composition #13: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #14: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #15: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #16: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #17: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #18: Chang, Fang-Rong., Chen, Keh-Shaw., Ko, Feng-Nien., Teng, Che-Ming., Wu, Yang-Chang. Bioactive alkaloids from Annona reticulata. chinese pharmaceutical journal, 1995, vol. 47, no. 5, p. 483–491. .
Composition #19: Yu, J. G., Liu, D., Xu, L. Z., Yang, S. L. Studies on chemical structures of two iso-acetogenins from Annona reticulata . yaoxue xuebao, 1997, vol. 32, no. 12, p. 914–919. .
Composition #20: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #21: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #22: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #23: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #24: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #25: Forgacs, P., Desconclois, J.F., Mansard, D. Dopamine and tetrahydroisoquinoline alkaloids of Annona reticulata DOPAMINE ET ALCALOIDES TETRAHYDROISOQUINOLEIQUES D'ANNONA RETICULATA L. ANNONACEES . plantes medicinales et phytotherapie, 1981, vol. 15, no. 1, p. 10–15. .
Composition #26: Jamkhande, P.G., Wattamwar, A.S., Chandak, P.G. In vitro anthelmintic efficacy of ethno-medicinal plant Annona reticulata L. roots against Indian earthworms (Pheretima posthuma). indian journal of natural products and resources, 2014, vol. 5, no. 2, p. 152–157. .
Composition #27: Jamkhande, P.G., Wattamwar, A.S., Chandak, P.G. In vitro anthelmintic efficacy of ethno-medicinal plant Annona reticulata L. roots against Indian earthworms (Pheretima posthuma). indian journal of natural products and resources, 2014, vol. 5, no. 2, p. 152–157. .
Composition #28: Jamkhande, P.G., Wattamwar, A.S., Chandak, P.G. In vitro anthelmintic efficacy of ethno-medicinal plant Annona reticulata L. roots against Indian earthworms (Pheretima posthuma). indian journal of natural products and resources, 2014, vol. 5, no. 2, p. 152–157. .
Composition #29: Jamkhande, P.G., Wattamwar, A.S., Chandak, P.G. In vitro anthelmintic efficacy of ethno-medicinal plant Annona reticulata L. roots against Indian earthworms (Pheretima posthuma). indian journal of natural products and resources, 2014, vol. 5, no. 2, p. 152–157. .
Composition #30: Chang, FR., Chen, JL., Chiu, HF., Wu, MJ., Wu, YC. Acetogenins from seeds of Annona reticulata. phytochemistry, 1998, vol. 47, no. 6, p. 1057–1061. DOI: 10.1016/S0031-9422(97)00675-4. [DOI link]
Composition #31: Pino, JA., Marbot, R., Fuentes, V. Characterization of volatiles in bullock's heart (Annona reticulata L.) fruit cultivars from Cuba . journal of agricultural and food chemistry, 2003, vol. 51, no. 13, p. 3836–3839. DOI: 10.1021/jf020733y. [DOI link]
Composition #32: Castro-Moreno, Marisol., Leonor Tinoco-Ojanguren, Clara., del Rocio Cruz-Ortega, Ma., Rosa Gonzalez-Esquinca, Alma. Influence of seasonal variation on the phenology and liriodenine content of Annona lutescens (Annonaceae) . journal of plant research, 2013, vol. 126, no. 4, p. 529–537. DOI: 10.1007/s10265-013-0550-x. [DOI link]
Composition #33: Castro-Moreno, Marisol., Leonor Tinoco-Ojanguren, Clara., del Rocio Cruz-Ortega, Ma., Rosa Gonzalez-Esquinca, Alma. Influence of seasonal variation on the phenology and liriodenine content of Annona lutescens (Annonaceae) . journal of plant research, 2013, vol. 126, no. 4, p. 529–537. DOI: 10.1007/s10265-013-0550-x. [DOI link]
Composition #34: SAAD, JM., HUI, YH., RUPPRECHT, JK., ANDERSON, JE., KOZLOWSKI, JF., ZHAO, GX., WOOD, KV., MCLAUGHLIN, JL. RETICULATACIN - A NEW BIOACTIVE ACETOGENIN FROM ANNONA-RETICULATA (ANNONACEAE) . tetrahedron, 1991, vol. 47, no. 16-17, p. 2751–2756. DOI: 10.1016/S0040-4020(01)87082-4. [DOI link]
Composition #35: SAAD, JM., HUI, YH., RUPPRECHT, JK., ANDERSON, JE., KOZLOWSKI, JF., ZHAO, GX., WOOD, KV., MCLAUGHLIN, JL. RETICULATACIN - A NEW BIOACTIVE ACETOGENIN FROM ANNONA-RETICULATA (ANNONACEAE) . tetrahedron, 1991, vol. 47, no. 16-17, p. 2751–2756. DOI: 10.1016/S0040-4020(01)87082-4. [DOI link]
Composition #36: WU, YC., CHANG, FR., DUH, CY., WANG, SK. ANNORETICUIN AND ISOANNORETICUIN - 2 NEW CYTOTOXIC ACETOGENINS FROM ANNONA-RETICULATA . heterocycles, 1992, vol. 34, no. 4, p. 667–674. .
Composition #37: CHANG, FR., WU, YC., DUH, CY. STUDIES ON THE ACETOGENINS OF FORMOSAN ANNONACEOUS PLANTS .2. CYTOTOXIC ACETOGENINS FROM ANNONA-RETICULATA . journal of natural products, 1993, vol. 56, no. 10, p. 1688–1694. DOI: 10.1021/np50100a005. [DOI link]
Composition #38: TAM, VT., HIEU, PQC., CHAPPE, B., ROBLOT, F., FIGADERE, B., CAVE, A. ACETOGENINS OF ANNONACEAE .37. RETICULATAIN-1 AND RETICULATAIN-2 WITH RETICULATAMONE - 3 NEW POLYKETIDES FROM THE SEEDS OF ANNONA-RETICULATA . bulletin de la societe chimique de france, 1995, vol. 132, no. 3, p. 324–329. .
Composition #39: Chen, YY., Chang, FR., Yen, HF., Wu, YC. Epomusenins A and B, two acetogenins from fruits of Rollinia mucosa. phytochemistry, 1996, vol. 42, no. 4, p. 1081–1083. DOI: 10.1016/0031-9422(96)00050-7. [DOI link]