EFSA
ecomole
vscht
  2. Cherimoya (as plant) // Annona cherimola Mill.

Cherimoya (as plant) // Annona cherimola Mill.

Family:
Annonaceae
Approval state:
Approved
Number of articles retrieved:
814
Number of processed references:
22
Compositions
#1: xylomaticin and gonionenin in the seeds #2: acetogenins - neoannonin, itrabin, almunequin, asimicin, squamocin, motrilin, cherimolin-1 and -2, tucumarin - seed #3: annocherine A - stem #4: (+)-syringaresinol (3), (+)-dia-syringaresinol, (+)-epi-syringaresinol - stem #5: lignans - liriodendrin - stem #6: norisocorydine in the stem #7: benzylisoquinolilne alkaloids: annocherin acetate, annocherin tri-TMSi derivative, 2,4-cis and trans-annocherinones, its diacetates and di-TMSi derivatives - seed #8: annocherine A - seed #9: (2,4)-cis-and trans-isoannonacins - seed #10: cis-Annonacin - seed #11: romucosine H - stem #12: cherianoine- stem #13: annocherin B - stem #14: annocherin A - stem #15: acetogenins - annomolin, annocherimolin - seed #16: annomontacin - seed #17: annomocherin - seed #18: annonacin - seed #19: annocherine C (isoquinoline alkaloid) in the leaves #20: (-)-anolobine, in the leaves #21: oxonantenine, in the leaves #22: aporphine alkaloids ( (-)-xylopine, oxoxylopine) in the leaves #23: (-)-asimilobine,in the leaves #24: liriodenine in the leaves #25: Rolliniastatin 2, laherradurin and squamocin #26: acetogenins - annomolon A and B, 34-epi-Annomolon A and B - seed #27: tetrahydrorotoberberine alkaloids (corytenchine and isocoreximine) in the roots #28: acetogenins in seeds #29: acetogenins - squamocin, molvizarin, itrabin, almuñequin, cherimolin-1, cherimolin-2, tucumanin - seed #30: kaurenoic acids in fruits #31: anonaine - aerial parts #32: alkaloids - 1,2-dimethoxy-5, 6.6 to 7-tetrahydro-4H-dibenzoquinoline-3,8,9,10-tetraol - aerial parts #33: liriodenine - aerial parts #34: nornuciferine - aerial parts #35: acetogenins - molvizarin, motrilin - seed #36: acetogenins - jetein, itrabin - seed #37: alkaloid - norushisunine - root #38: liriodenine - root #39: acetogenins - annosenegalin, Gigantetrocin - seed #40: annonacin A - seed #41: isocorydine in the stem #42: norisocorydine in the stem #43: anolobine in the stem #44: liriodenine in the stem #45: asimilobine in the stem #46: oxoglaucine in the stem #47: anonaine in the stem #48: atherospermidine in the stem #49: kaurane derivatives ent-lcaur-16-en-19-oic acid, kauran-19-oic acid, and 161l-hydroxy-17-acetoxy-ent-kauran-19-oic acid in the stem #50: aporphine alkaloids in the stem #51: alkaloids (ushinsunine, norushinsunin, N-methyllaurotetanine, oxoxylopine, methylasimilobine, stepharine, kikemanine) in the stem
Endpoint Studies
Genotoxicity
#1: 2.5 µg/mL itrabin and squamocin - mutagenic effects against Alllium cepa cells
Composition #1: Kim, Dal Hwan., Fang, Zhe., Lee, Young Eun., Woo, Mi Hee. Xylomaticin and gonionenin, cytotoxic annonaceous acetogenins from the seeds of Annona cherimolia. natural product sciences, 2007, vol. 13, no. 4, p. 355–358. .
Composition #2: Alvarez Colom, O., Neske, A., Popich, S., Bardón, A. Toxic effects of annonaceous acetogenins from Annona cherimolia (Magnoliales: Annonaceae) on Spodoptera frugiperda (Lepidoptera: Noctuidae). journal of pest science, 2007, vol. 80, no. 1, p. 63–67. DOI: 10.1007/s10340-006-0149-2. [DOI link]
Composition #3: Chen, CY., Wu, TY., Chang, FR., Wu, YC. Lignans and kauranes from the stems of Annona cherimola. journal of the chinese chemical society, 1998, vol. 45, no. 5, p. 629–634. .
Composition #4: Chen, CY., Wu, TY., Chang, FR., Wu, YC. Lignans and kauranes from the stems of Annona cherimola. journal of the chinese chemical society, 1998, vol. 45, no. 5, p. 629–634. .
Composition #5: Chen, CY., Wu, TY., Chang, FR., Wu, YC. Lignans and kauranes from the stems of Annona cherimola. journal of the chinese chemical society, 1998, vol. 45, no. 5, p. 629–634. .
Composition #6: Chen, CY., Chang, FR., Teng, CM., Wu, YC. Cheritamine, a new N-fatty acyl tryptamine and other constituents from the stems of Annona cherimola . journal of the chinese chemical society, 1999, vol. 46, no. 1, p. 77–86. .
Composition #7: Woo, MH., Kim, DH., Fotopoulos, SS., McLaughlin, JL. Annocherin and (2,4)-cis- and trans-annocherinones, monotetrahydrofuran annonaceous acetogenins with a C-7 carbonyl group from Annona cherimolia seeds . journal of natural products, 1999, vol. 62, no. 9, p. 1250–1255. DOI: 10.1021/np990135m. [DOI link]
Composition #8: Woo, MH., Kim, DH., Fotopoulos, SS., McLaughlin, JL. Annocherin and (2,4)-cis- and trans-annocherinones, monotetrahydrofuran annonaceous acetogenins with a C-7 carbonyl group from Annona cherimolia seeds . journal of natural products, 1999, vol. 62, no. 9, p. 1250–1255. DOI: 10.1021/np990135m. [DOI link]
Composition #9: Woo, MH., Chung, SO., Kim, DH. cis-Annonacin and (2,4)-cis-and trans-isoannonacins: Cytotoxic monotetrahydrofuran annonaceous acetogenins from the seeds of Annona cherimolia . archives of pharmacal research, 1999, vol. 22, no. 5, p. 524–528. DOI: 10.1007/BF02979164. [DOI link]
Composition #10: Woo, MH., Chung, SO., Kim, DH. cis-Annonacin and (2,4)-cis-and trans-isoannonacins: Cytotoxic monotetrahydrofuran annonaceous acetogenins from the seeds of Annona cherimolia . archives of pharmacal research, 1999, vol. 22, no. 5, p. 524–528. DOI: 10.1007/BF02979164. [DOI link]
Composition #11: Chen, CY., Chang, FR., Pan, WB., Wu, YC. Four alkaloids from Annona cherimola. phytochemistry, 2001, vol. 56, no. 7, p. 753–757. DOI: 10.1016/S0031-9422(00)00486-6. [DOI link]
Composition #12: Chen, CY., Chang, FR., Pan, WB., Wu, YC. Four alkaloids from Annona cherimola. phytochemistry, 2001, vol. 56, no. 7, p. 753–757. DOI: 10.1016/S0031-9422(00)00486-6. [DOI link]
Composition #13: Chen, CY., Chang, FR., Pan, WB., Wu, YC. Four alkaloids from Annona cherimola. phytochemistry, 2001, vol. 56, no. 7, p. 753–757. DOI: 10.1016/S0031-9422(00)00486-6. [DOI link]
Composition #14: Chen, CY., Chang, FR., Pan, WB., Wu, YC. Four alkaloids from Annona cherimola. phytochemistry, 2001, vol. 56, no. 7, p. 753–757. DOI: 10.1016/S0031-9422(00)00486-6. [DOI link]
Composition #15: Kim, DH., Ma, FS., Suk, KD., Son, JK., Lee, JS., Woo, MH. Annomolin and annocherimolin, new cytotoxic annonaceous acetogenins from Annona cherimolia seeds . journal of natural products, 2001, vol. 64, no. 4, p. 502–506. DOI: 10.1021/np000335u. [DOI link]
Composition #16: Kim, DH., Son, JK., Woo, MH. Annomocherin, annonacin and annomontacin: A novel and two known bioactive mono-tetrahydrofuran annonaceous acetogenins from Annona cherimolia seeds . archives of pharmacal research, 2001, vol. 24, no. 4, p. 300–306. DOI: 10.1007/BF02975096. [DOI link]
Composition #17: Kim, DH., Son, JK., Woo, MH. Annomocherin, annonacin and annomontacin: A novel and two known bioactive mono-tetrahydrofuran annonaceous acetogenins from Annona cherimolia seeds . archives of pharmacal research, 2001, vol. 24, no. 4, p. 300–306. DOI: 10.1007/BF02975096. [DOI link]
Composition #18: Kim, DH., Son, JK., Woo, MH. Annomocherin, annonacin and annomontacin: A novel and two known bioactive mono-tetrahydrofuran annonaceous acetogenins from Annona cherimolia seeds . archives of pharmacal research, 2001, vol. 24, no. 4, p. 300–306. DOI: 10.1007/BF02975096. [DOI link]
Composition #19: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #20: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #21: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #22: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #23: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #24: Chen, CY., Wu, YC. Annocherine C, a new C-alpha hydroxy benzylisoquinoline and other constituents from the leaves of Annona cherimola . journal of the chinese chemical society, 2001, vol. 48, no. 6B, p. 1203–1206. .
Composition #25: Gonzalez-Coloma, A., Guadano, A., de Ines, C., Martinez-Diaz, R., Cortes, D. Selective action of acetogenin mitochondrial complex I inhibitors. zeitschrift fur naturforschung c-a journal of biosciences, 2002, vol. 57, no. 11-12, p. 1028–1034. .
Composition #26: Son, JK., Kim, DH., Woo, MH. Two new epimeric pairs of acetogenins bearing a carbonyl group from Annona cherimolia seeds . journal of natural products, 2003, vol. 66, no. 10, p. 1369–1372. DOI: 10.1021/np0301487. [DOI link]
Composition #27: Martinez-Vazquez, M., Lozano, DGDC., Estrada-Reyes, R., Gonzalez-Lugo, NM., Apan, TR., Heinze, G. Bio-guided isolation of the cytotoxic corytenchine and isocoreximine from roots of Annona cherimolia . fitoterapia, 2005, vol. 76, no. 7-8, p. 733–736. DOI: 10.1016/j.fitote.2005.08.004. [DOI link]
Composition #28: Garcia-Aguirre, Karol Karla., Zepeda-Vallejo, Luis Gerardo., Ramon-Gallegos, Eva., Alvarez-Gonzalez, Isela., Madrigal-Bujaidar, Eduardo. Genotoxic and Cytotoxic Effects Produced by Acetogenins Obtained from Annona cherimolia MILL. . biological & pharmaceutical bulletin, 2008, vol. 31, no. 12, p. 2346–2349. DOI: 10.1248/bpb.31.2346. [DOI link]
Composition #29: Alvarez Colom, Olga., Salvatore, Analia., Willink, Eduardo., Ordonez, Roxana., Isla, Maria I., Neske, Adriana., Bardon, Alicia. Insecticidal, Mutagenic and Genotoxic Evaluation of Annonaceous Acetogenins . natural product communications, 2010, vol. 5, no. 3, p. 391–394. .
Composition #30: Guillope, R., Escobar-Khondiker, M., Guerineau, V., Laprevote, O., Hoeglinger, G. U., Champy, P. Kaurenoic Acid from Pulp of Annona cherimolia in regard to Annonaceae-induced Parkinsonism . phytotherapy research, 2011, vol. 25, no. 12, p. 1861–1864. DOI: 10.1002/ptr.3508. [DOI link]
Composition #31: Martinez-Vazquez, Mariano., Estrada-Reyes, Rosa. SECONDARY METABOLISMIN IN ANNONACEAE: POTENCIAL SOURCE OF DRUGS. revista brasileira de fruticultura, 2014, vol. 36, no. 1, p. 141–146. .
Composition #32: Martinez-Vazquez, Mariano., Estrada-Reyes, Rosa. SECONDARY METABOLISMIN IN ANNONACEAE: POTENCIAL SOURCE OF DRUGS. revista brasileira de fruticultura, 2014, vol. 36, no. 1, p. 141–146. .
Composition #33: Martinez-Vazquez, Mariano., Estrada-Reyes, Rosa. SECONDARY METABOLISMIN IN ANNONACEAE: POTENCIAL SOURCE OF DRUGS. revista brasileira de fruticultura, 2014, vol. 36, no. 1, p. 141–146. .
Composition #34: Martinez-Vazquez, Mariano., Estrada-Reyes, Rosa. SECONDARY METABOLISMIN IN ANNONACEAE: POTENCIAL SOURCE OF DRUGS. revista brasileira de fruticultura, 2014, vol. 36, no. 1, p. 141–146. .
Composition #35: CORTES, D., MYINT, SH., HOCQUEMILLER, R. ACETOGENINS OF ANNONACEAE .12. MOLVIZARIN AND MOTRILIN - 2 NOVEL CYTOTOXIC BIS-TETRAHYDROFURANIC GAMMA-LACTONE ACETOGENINS FROM ANNONA-CHERIMOLIA . tetrahedron, 1991, vol. 47, no. 38, p. 8195–8202. DOI: 10.1016/S0040-4020(01)91014-2. [DOI link]
Composition #36: CORTES, D., MYINT, SH., LEBOEUF, M., CAVE, A. ACETOGENINS OF ANNONACEAE .13. A NEW TYPE OF CYTOTOXIC ACETOGENINS - THE TETRAHYDROFURANIC BETA-HYDROXY METHYL GAMMA-LACTONES . tetrahedron letters, 1991, vol. 32, no. 43, p. 6133–6134. DOI: 10.1016/0040-4039(91)80771-W. [DOI link]
Composition #37: CHULIA, S., NOGUERA, MA., IVORRA, MD., CORTES, D., DOCON, MP. VASODILATOR EFFECTS OF LIRIODENINE AND NORUSHINSUNINE, 2 APORPHINE ALKALOIDS ISOLATED FROM ANNONA-CHERIMOLIA, IN RAT AORTA . pharmacology, 1995, vol. 50, no. 6, p. 380–387. DOI: 10.1159/000139307. [DOI link]
Composition #38: CHULIA, S., NOGUERA, MA., IVORRA, MD., CORTES, D., DOCON, MP. VASODILATOR EFFECTS OF LIRIODENINE AND NORUSHINSUNINE, 2 APORPHINE ALKALOIDS ISOLATED FROM ANNONA-CHERIMOLIA, IN RAT AORTA . pharmacology, 1995, vol. 50, no. 6, p. 380–387. DOI: 10.1159/000139307. [DOI link]
Composition #39: Sahpaz, S., Gonzalez, MC., Hocquemiller, R., ZafraPolo, MC., Cortes, D. Annosenegalin and annogalene: Two cytotoxic mono-tetrahydrofuran acetogenins from Annona senegalensis and Annona cherimolia . phytochemistry, 1996, vol. 42, no. 1, p. 103–107. DOI: 10.1016/0031-9422(95)00891-8. [DOI link]
Composition #40: Sahpaz, S., Gonzalez, MC., Hocquemiller, R., ZafraPolo, MC., Cortes, D. Annosenegalin and annogalene: Two cytotoxic mono-tetrahydrofuran acetogenins from Annona senegalensis and Annona cherimolia . phytochemistry, 1996, vol. 42, no. 1, p. 103–107. DOI: 10.1016/0031-9422(95)00891-8. [DOI link]
Composition #41: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #42: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #43: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #44: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #45: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #46: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #47: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #48: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #49: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #50: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Composition #51: Chen, CY., Chang, FR., Wu, YC. The constituents from the stems of Annona cherimola. journal of the chinese chemical society, 1997, vol. 44, no. 3, p. 313–319. .
Genotox #1: Alvarez Colom, Olga., Salvatore, Analia., Willink, Eduardo., Ordonez, Roxana., Isla, Maria I., Neske, Adriana., Bardon, Alicia. Insecticidal, Mutagenic and Genotoxic Evaluation of Annonaceous Acetogenins . natural product communications, 2010, vol. 5, no. 3, p. 391–394. .