Draft - work in progress
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- Angelica pubescens Maxim.
Angelica pubescens Maxim.
- Family:
- Apiaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 549
- Number of processed references:
- 5
Compositions
#1: angelol in roots
#2: glabra-lactone in roots
#3: Umbelliferone, ulopterol, peucedanol, oxypeucedanin hydrate, nodakenin, apiosylskimmin, daucosterol, sucrose, adenosine, and 2,3,4,9-tetrahydro-1H-pyrido-(3,4-b)indole-3-carboxylic acid
#4: Furanocoumarins in roots and rhizomes columbianedin, osthol, bergapten , isoimperatorin, angelidiol, nodakenetin, marmesinin, columbianin and meranzin hydrat)
#5: 6-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosyl-scopoletin,
7-O-β-D-glucopyranosyl- umbelliferone,
marmesinin,
7-O-β-D-apiofuranosyl-(1→6)-β-D- glucopyranosyl-umbelliferone (IV),
angelitriol
#6: coumarins (psoralen, xanthotoxin, bergapten, bergaptol, isoimperatorin, imperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, umbelliferone, scopoletin, osthole, meranzin hydrate and nodakenetin) in roots
Composition #1: Hata, K., Kozawa, M. Constitution of angelol, a new coumarin isolated from the root of Angelica pubescens. tetrahedron letters, 1965, vol. (50), p. 4557–62. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethereal
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
angelol
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Analytical method code:
Chromatographic tests (F015A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
angelol in roots
Composition #2: Hata, K., Kozawa, M. Constitution of angelol, a new coumarin isolated from the root of Angelica pubescens. tetrahedron letters, 1965, vol. (50), p. 4557–62. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethereal
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
glabra-lactone
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Analytical method code:
Chromatographic tests (F015A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
glabra-lactone in roots
Composition #3: Liu, Jianghua., Tan, Yan., Chen, Yuping., Xu, Suixu., Yao, Xinsheng. Chemical constituents of Angelica pubescens. zhongcaoyao, 1994, vol. 25, no. 6, p. 288–91. .
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
Umbelliferone, ulopterol, peucedanol, oxypeucedanin hydrate, nodakenin, apiosylskimmin, daucosterol, sucrose, adenosine, and 2,3,4,9-tetrahydro-1H-pyrido-(3,4-b)indole-3-carboxylic ac
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Umbelliferone, ulopterol, peucedanol, oxypeucedanin hydrate, nodakenin, apiosylskimmin, daucosterol, sucrose, adenosine, and 2,3,4,9-tetrahydro-1H-pyrido-(3,4-b)indole-3-carboxylic acid
Composition #4: Liu, Jianghua., Xu, Suixu., Meng, Zhiyun., Yao, Xinsheng., Wu, Yuqiang. Further isolation of coumarin from Angelica pubescens Maxim f. Shan et Yuan. journal of chinese pharmaceutical sciences, 1997, vol. 6, no. 4, p. 221–224. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
80% ethanol
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Substance:
Furanocoumarins (RF-00004381-PAR)
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Additional substance description:
columbianedin, osthol, bergapten , isoimperatorin, angelidiol, nodakenetin, marmesinin, columbianin and meranzin hydrate
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Furanocoumarins in roots and rhizomes columbianedin, osthol, bergapten , isoimperatorin, angelidiol, nodakenetin, marmesinin, columbianin and meranzin hydrat)
Composition #5: Ding, Xifei., Feng, Xu., Dong, Yunfa., Zhao, Xingzeng., Chen, Yu., Liang, Yongqi. Study on coumarins of Angelica pubescens. zhongchengyao, 2009, vol. 31, no. 7, p. 1102–1104. .
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
6-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosyl-scopoletin, 7-O-β-D-glucopyranosyl- umbelliferone, marmesinin, 7-O-β-D-apiofuranosyl-(1→6)-β-D- glucopyranosyl-umbelliferone (IV), angelitriol
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
6-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranosyl-scopoletin,
7-O-β-D-glucopyranosyl- umbelliferone,
marmesinin,
7-O-β-D-apiofuranosyl-(1→6)-β-D- glucopyranosyl-umbelliferone (IV),
angelitriol
Composition #6: Yang, Yan-Fang., Zhang, Lei., Zhang, You-Bo., Yang, Xiu-Wei. Simultaneous assessment of absorption characteristics of coumarins from Angelicae Pubescentis Radix: In vitro transport across Caco-2 cell and in vivo pharmacokinetics in rats after oral administration. journal of chromatography b: analytical technologies in the biomedical and life sciences, 2017, vol. 1060, p. 308–315. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol - water
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Substance:
coumarins (RF-00004351-PAR)
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Additional substance description:
psoralen, xanthotoxin, bergapten, bergaptol, isoimperatorin, imperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, umbelliferone, scopoletin, osthole, meranzin hydrate and nodakenetin
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Analytical method code:
UHPLC-MS-MS (F608A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
coumarins (psoralen, xanthotoxin, bergapten, bergaptol, isoimperatorin, imperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, umbelliferone, scopoletin, osthole, meranzin hydrate and nodakenetin) in roots
