EFSA Compendium of Botanicals

Draft - work in progress

Angelica polymorpha Maxim.

Family:: Apiaceae
Approval state:: Approved
Number of articles retrieved:: 340
Number of processed references:: 4

Compositions

#1: octanal #2: ligustilide #3: saxalin #4: umbelliferone #5: Bisabolangelone #6: pabulenol #7: Bergapten in rhizome #8: Isooxypeucedanin in rhizome #9: Isoimperatorin in rhizome #10: Isopimpellin in rhizome #11: Phellopterin in rhizome #12: Imperatorin in rhizome #13: Osthol in rhizome #14: Columbianidin in rhizome

Endpoint Studies

Genotoxicity

Composition #1: Dan, Feijun., Cai, Zhengjun., Lin, Shilong., Pan, Jiarong., Wang, Li. Analysis of components in volatile oil by different extraction methods of Angelica polymorpha maxim.. jingxi huagong, 2009, vol. 26, no. 5, p. 468–471. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

octanal (RF-00003961-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

octanal

Composition #2: Dan, Feijun., Cai, Zhengjun., Lin, Shilong., Pan, Jiarong., Wang, Li. Analysis of components in volatile oil by different extraction methods of Angelica polymorpha maxim.. jingxi huagong, 2009, vol. 26, no. 5, p. 468–471. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

ligustilide (RF-00003900-PAR)
Analytical method code:

GC-MS (F046A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

ligustilide

Composition #3: Yang, Yu., Yu, Neng-jiang., Liang, Fei-fei., Zhang, Yang., Ren, Feng-xia., Zhang, Ai-jun., Zhao, Yi-min. Studies on chemical constituents of Angelica polymorpha Maxim (II). jiefangjun yaoxue xuebao, 2010, vol. 26, no. 3, p. 189–191. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform and alcohol
Substance:

saxalin (RF-00004046-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saxalin

Composition #4: Yang, Yu., Yu, Neng-jiang., Liang, Fei-fei., Zhang, Yang., Ren, Feng-xia., Zhang, Ai-jun., Zhao, Yi-min. Studies on chemical constituents of Angelica polymorpha Maxim (II). jiefangjun yaoxue xuebao, 2010, vol. 26, no. 3, p. 189–191. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform and alcohol
Substance:

umbelliferone (RF-00004096-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

umbelliferone

Composition #5: Cai, Zheng-jun., Dan, Fei-jun., Cheng, Fan., Wang, Jun-zhi., Zou, Kun. Chemical constituents of antibacterial activity fraction of Angelica polymorpha . . zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2008, vol. 31, no. 8, p. 1160–2. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

bisabolangelone (RF-00003714-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Bisabolangelone

Composition #6: Cai, Zheng-jun., Dan, Fei-jun., Cheng, Fan., Wang, Jun-zhi., Zou, Kun. Chemical constituents of antibacterial activity fraction of Angelica polymorpha . . zhong yao cai = zhongyaocai = journal of chinese medicinal materials, 2008, vol. 31, no. 8, p. 1160–2. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

pabulenol (RF-00003970-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pabulenol

Composition #7: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

Bergapten (RF-00003837-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

high-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Bergapten in rhizome

Composition #8: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

isooxypeucedanin (RF-00003882-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isooxypeucedanin in rhizome

Composition #9: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

isoimperatorin (RF-00003880-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isoimperatorin in rhizome

Composition #10: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

Isopimpinellin (RF-00003784-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Isopimpellin in rhizome

Composition #11: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

Phellopterin (RF-00003560-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Phellopterin in rhizome

Composition #12: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

imperatorin (RF-00003874-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Imperatorin in rhizome

Composition #13: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

osthol (RF-00011008-PAR)
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

High-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Osthol in rhizome

Composition #14: Liu, Na., Yu, Nengjiang J., Li, Jin., Yang, Yu., Guo, Jifen F., Zhao, Yimin M. Simultaneous Qualitative Analysis of Coumarins in the Rhizome of Angelica polymorpha Maxim. by LC-DAD-ESI-MS . chromatographia, 2011, vol. 73, no. 11-12, p. 1121–1129. DOI: 10.1007/s10337-011-2008-4. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % alcohol extract
Substance:

Columbianadin (RF-00011112-PAR)
Additional substance description:

columbianadin
Analytical method code:

HPLC-MS/MS (F698A)
Analytical method - additional description:

high-performance liquid chromatography (LC)–photodiode array detection (DAD)–electrospray ionization (ESI)–tandem mass spectrometry (MS)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Columbianidin in rhizome