EFSA
ecomole
vscht
  2. Angelica archangelica L. // Archangelica officinalis Hoffm.

Angelica archangelica L. // Archangelica officinalis Hoffm.

Family:
Apiaceae
Approval state:
Approved
Number of articles retrieved:
712
Number of processed references:
14
Compositions
#1: bergapten in the seeds #2: xanthotoxin in the seeds #3: imperatorin in the seeds #4: umbelliprenin in the seeds #5: furanocoumarins (angelicin, osthol, ostenol) in the seeds #6: xanthotoxol in the seeds #7: furanocoumarins (angelicin, umbelliferone, osthole, osthenol, kvannin, archangelicin, archangin) in the roots #8: angelicin #9: bergapten #10: osthol #11: furocumarins - prangolarine, archangelin- root #12: angelicin - root #13: furanocoumarins (phellopterin, ostrutol) in the fruits #14: Furanocoumarins (umbelliprenin, isoimperatorin, bergapten, prangolarin, ostruthol, and oxypeucedanin hydrate) in the seed #15: oxypeucedanin, oxypeucedanin, oxypeucedanin hydrate, pimpinellin, isopimpinellin in the seeds #16: imperatorin - fruit #17: phellopterin - seed #18: archangelicin - seed #19: imperatorin - seed #20: isoimperatorin - seed #21: bergapten - seed #22: xanthotoxin - seed #23: coumarins in the leaves #24: 8.3 % bergapten in the seeds #25: prangenin in the seeds #26: 14.3% phellopterin in the seeds #27: 46.5% imperatorin in the seeds #28: 9% oxypeucedanin in the seeds #29: 7.2 % xanthotoxin in the seeds #30: 10.4% isoimperatorin in the seeds #31: isoimperatorin - seed #32: phellopterin - seed #33: imperatorin - seed #34: bergapten- seed #35: methoxsalen - seed #36: isopimpinellin - bark #37: furocoumarins - bark #38: phellopterin - bark #39: oxypeucedanin hydrate - bark #40: imperatorin - bark #41: bergapten - fruit #42: umbelliferone - fruit #43: xanthotoxol - fruit #44: isopimpinellin - fruit #45: isoimperatorin - fruit
Endpoint Studies
Genotoxicity
#1: photoinduced mutagenicity
Composition #1: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #2: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #3: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #4: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #5: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #6: Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. monatshefte fuer chemie, 1938, vol. 72, p. 179–89. .
Composition #7: Svendsen, Anders Baerheim. Chemistry of Norwegian Umbelliferae. johan grundt tanum forlag, oslo, 1954, p. 144 pp. .
Composition #8: Brown, Stewart A., Shyluk, J. P. Gas-liquid chromatography of some naturally occurring coumarins. anal. chem., 1962, vol. 34, p. 1058–61. .
Composition #9: Brown, Stewart A., Shyluk, J. P. Gas-liquid chromatography of some naturally occurring coumarins. anal. chem., 1962, vol. 34, p. 1058–61. .
Composition #10: Brown, Stewart A., Shyluk, J. P. Gas-liquid chromatography of some naturally occurring coumarins. anal. chem., 1962, vol. 34, p. 1058–61. .
Composition #11: Chatterjee, A., Sen Gupta, S. Constitution of archangelin, a new coumarin isolated from the root of Angelica archangelica. tetrahedron letters, 1964, vol. (29-30), p. 1961–5. .
Composition #12: Chatterjee, A., Sen Gupta, S. Constitution of archangelin, a new coumarin isolated from the root of Angelica archangelica. tetrahedron letters, 1964, vol. (29-30), p. 1961–5. .
Composition #13: Dranitsyna, Yu. A., Pigulevskii, G. V., Bukreeva, T. V. Coumarins from fruits of Angelica archangelica. zhurnal prikladnoi khimii (sankt-peterburg, russian federation), 1965, vol. 38, no. 11, p. 2570–5. .
Composition #14: Chatterjee, Asima., Chakravarty, A., Mukherjee, Rabindranath. Chemistry of the seeds of Angelica archangelica. journal of the indian chemical society, 1967, vol. 44, no. 2, p. 110–14. .
Composition #15: Glowniak, Kazimierz., Gawron, Antoni., Kwietniewska, Barbara. Study of the coumarins of Archangelica officinalis Hoffm. fruit. annales universitatis mariae curie-sklodowska, sectio d: medicina, 1976, vol. 31, p. 349–54. .
Composition #16: Luszczki, Jarogniew J., Andres-Mach, Marta., Glensk, Michal., Skalicka-Wozniak, Krystyna. Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study. pharmacological reports, 2010, vol. 62, no. 6, p. 1231–1236. .
Composition #17: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #18: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #19: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #20: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #21: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #22: Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277–285. .
Composition #23: Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H., Hiltunen, R. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins . planta medica, 1999, vol. 65, no. 8, p. 715–718. DOI: 10.1055/s-1999-14049. [DOI link]
Composition #24: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #25: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #26: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #27: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #28: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #29: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #30: Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1–7. .
Composition #31: Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . industrial crops and products, 2013, vol. 51, p. 87–92. DOI: 10.1016/j.indcrop.2013.08.073. [DOI link]
Composition #32: Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . industrial crops and products, 2013, vol. 51, p. 87–92. DOI: 10.1016/j.indcrop.2013.08.073. [DOI link]
Composition #33: Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . industrial crops and products, 2013, vol. 51, p. 87–92. DOI: 10.1016/j.indcrop.2013.08.073. [DOI link]
Composition #34: Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . industrial crops and products, 2013, vol. 51, p. 87–92. DOI: 10.1016/j.indcrop.2013.08.073. [DOI link]
Composition #35: Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . industrial crops and products, 2013, vol. 51, p. 87–92. DOI: 10.1016/j.indcrop.2013.08.073. [DOI link]
Composition #36: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]
Composition #37: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]
Composition #38: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]
Composition #39: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]
Composition #40: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]
Composition #41: Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166–1171. DOI: 10.5935/0103-5053.20140093. [DOI link]
Composition #42: Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166–1171. DOI: 10.5935/0103-5053.20140093. [DOI link]
Composition #43: Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166–1171. DOI: 10.5935/0103-5053.20140093. [DOI link]
Composition #44: Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166–1171. DOI: 10.5935/0103-5053.20140093. [DOI link]
Composition #45: Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166–1171. DOI: 10.5935/0103-5053.20140093. [DOI link]
Genotox #1: Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . food and chemical toxicology, 2014, vol. 68, p. 257–266. DOI: 10.1016/j.fct.2014.03.014. [DOI link]