EFSA
ecomole
vscht
  2. Anamirta paniculata Colebr. // Anamirta cocculus (L.) Wight & Arn.

Anamirta paniculata Colebr. // Anamirta cocculus (L.) Wight & Arn.

Family:
Menispermaceae
Approval state:
Approved
Number of articles retrieved:
67
Number of processed references:
7
Compositions
#1: Picrotoxin in fruits #2: 1.2 % of picrotoxin in the seeds ethanol extract #3: methyl picrotoxate in fruits #4: Three isoquinoline alkaloids: L-8-Oxotetrahydropalmatine 0.0008%, oxypalamatine 0.0005% and stepharine 0.0008 % in stem #5: triterpene saponins in the stem MeOH extract #6: picrotoxinin, methyl picrotoxate, picrotin, dihydroxypicrotoxinin, picrotoxic acid in seeds #7: Isoquinoline alkaloids in stem and roots
Endpoint Studies
Genotoxicity
Composition #1: Clark, E. P. Preparation of picrotoxin. journal of the american chemical society, 1935, vol. 57, p. 1111. .
Composition #2: Amma, K. Pankajakshi. Chemical examination of plant products possessing insecticidal properties. bulletin of the research institute, university of kerala, trivandrum, series a: physical sciences, 1954, vol. 3(Ser. A), p. 129–32. .
Composition #3: Pradhan, P., Mamdapur, V. R., Sipahimalani, A. T. Methyl picrotoxate, a minor component of berries of plant Anamrita cocculus and its stereochemistry by high resolution NMR spectroscopy. indian journal of chemistry, section b: organic chemistry including medicinal chemistry, 1990, vol. 29B, no. 7, p. 676–7. .
Composition #4: Jayasinghe, U. L. B., Wannigama, G. P., Balasubramaniam, S., Nasir, Habib., Atta-ur-Rahman. Benzylisoquinoline alkaloids from Anamirta cocculus and Diploclisia glaucescens. journal of the national science council of sri lanka, 1992, vol. 20, no. 2, p. 187–90. .
Composition #5: Jayasinghe, U. L. B., Wannigama, G. P., Fujimoto, Y. Chemistry and bioactivity of saponins from some Sri Lankan plants. proceedings of the phytochemical society of europe, 2000, vol. 45(Saponins in Food, Feedstuffs and Medicinal Plants), p. 113–119. .
Composition #6: Agarwal, SK., Singh, SS., Verma, S., Kumar, S. Two picrotoxin derivatives from Anamirta cocculus. phytochemistry, 1999, vol. 50, no. 8, p. 1365–1368. DOI: 10.1016/S0031-9422(98)00692-X. [DOI link]
Composition #7: VERPOORTE, R., SIWON, J., TIEKEN, MEM., SVENDSEN, AB. STUDIES ON INDONESIAN MEDICINAL-PLANTS .5. THE ALKALOIDS OF ANAMIRTA-COCCULUS . journal of natural products, 1981, vol. 44, no. 2, p. 221–224. DOI: 10.1021/np50014a013. [DOI link]