EFSA Compendium of Botanicals

Draft - work in progress

Anabasis aphylla L.

Family:: Amaranthaceae
Approval state:: Approved
Number of articles retrieved:: 275
Number of processed references:: 5

Compositions

#1: aphyllidine, and aphylline in the plant #2: 0.06-0.32 % anabasine in the plant #3: 0-1.5% % lupinin in the plant #4: Quinolizidine alkaloids (oxaphyllidine, oxaphylline) in unspecified plant part #5: Pyridine alkaloids: anabasamine hydrochloride, anabasamine methioide, anabasine hydrochloride, anabasine methioide, anabasine sulfate, epilupinine hydrochloride, epilupinine methioide, lupinine hydrochloride, lupinine methioide, methylanaphylinate hydrochloride, methylanaphylinate methyoide, in an unspecified plant part #6: Quinolizidine alkaloids (aphylline, pachycarpine) in unspecified plant part #7: anabasamine in unspecified plant part #8: pyridine alkaloids in aerial parts #9: N-methylanabasine (RF-00003512-PAR) in aerial parts #10: anabasamine (RF-00004142-PAR) in aerial parts #11: isonicoteine (RF-00003449-PAR) in aerial parts

Endpoint Studies

Genotoxicity

Composition #1: Brutko, L. I., Massagetov, P. S. Lupinine content in Anabasis aphylla. meditsinskaya promyshlennost sssr, 1964, vol. 18, no. 12, p. 34–5. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

5% Ethanol
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Additional substance description:

aphyllidine, and aphylline
Analytical method - additional description:

Brutko and Utkin method
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

aphyllidine, and aphylline in the plant

Composition #2: Brutko, L. I., Massagetov, P. S. Lupinine content in Anabasis aphylla. meditsinskaya promyshlennost sssr, 1964, vol. 18, no. 12, p. 34–5. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

5% Ethanol
Substance:

anabasine (RF-00003682-PAR)
Analytical method - additional description:

Brutko and Utkin method
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.06-3.2
Internal remarks:

0.06-0.32 % anabasine in the plant

Composition #3: Brutko, L. I., Massagetov, P. S. Lupinine content in Anabasis aphylla. meditsinskaya promyshlennost sssr, 1964, vol. 18, no. 12, p. 34–5. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

5% Ethanol
Substance:

Lupinine (RF-00003912-PAR)
Analytical method - additional description:

Brutko and Utkin method
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.5
Internal remarks:

0-1.5% % lupinin in the plant

Composition #4: Sadykov, A. S., Aslanov, Kh. A., Kushmuradov, Yu. K. Quinolizidine alkaloids. abhandlungen der deutschen akademie der wissenschaften zu berlin, klasse fuer chemie, geologie und biologie, 1966, vol. (3), p. 279–86. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Additional substance description:

oxaphyllidine, oxaphylline
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Quinolizidine alkaloids (oxaphyllidine, oxaphylline) in unspecified plant part

Composition #5: Tilyabaev, Z., Abduvakhabov, A.A. Alkaloids of Anabasis aphylla and their cholinergic activities. chemistry of natural compounds, 1998, vol. 34, no. 3, p. 295–297. . [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

pyridine alkaloids (RF-00010801-PAR)
Additional substance description:

anabasamine hydrochloride, anabasamine methioide, anabasine hydrochl, anabasine methioide, anabasine sulfate, epilupinine hydrochl., epilupinine methioide, lupinine hydrochl, lupinine methioide, methylanaphylinate hydrochl and methyoide
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Pyridine alkaloids: anabasamine hydrochloride, anabasamine methioide, anabasine hydrochloride, anabasine methioide, anabasine sulfate, epilupinine hydrochloride, epilupinine methioide, lupinine hydrochloride, lupinine methioide, methylanaphylinate hydrochloride, methylanaphylinate methyoide, in an unspecified plant part

Composition #6: Yusupov, Sh., Ishbaev, A.I., Aslanov, Kh.A., Sadykov, A.S. Quantitative determination of the alkaloids of Anabasis aphylla by thin-layer chromatography. chemistry of natural compounds, 1976, vol. 12, no. 6, p. 692–695. DOI: 10.1007/BF00564961. [DOI link]

Language:

English (en)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform extraction
Substance:

Quinolizidine alkaloids (RF-00004327-PAR)
Additional substance description:

aphylline, pachycarpine
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Quinolizidine alkaloids (aphylline, pachycarpine) in unspecified plant part

Composition #7: Yusupov, Sh., Ishbaev, A.I., Aslanov, Kh.A., Sadykov, A.S. Quantitative determination of the alkaloids of Anabasis aphylla by thin-layer chromatography. chemistry of natural compounds, 1976, vol. 12, no. 6, p. 692–695. DOI: 10.1007/BF00564961. [DOI link]

Language:

English (en)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform extraction
Substance:

anabasamine (RF-00004142-PAR)
Analytical method code:

Gelpermeation, High Performance Thin Layer Chromatography (HPTLC) (F017A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anabasamine in unspecified plant part

Composition #8: Du, Hua., Wang, Ye., Yan, Chen., Zhou, Li-Gang., Hao, Xiao-Jiang. Alkaloids from Anabasis aphylla L.. journal of asian natural products research, 2008, vol. 10, no. 11, p. 1093–1095. DOI: 10.1080/10286020802318966. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

pyridine alkaloids
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

pyridine alkaloids in aerial parts

Composition #9: Du, Hua., Wang, Ye., Yan, Chen., Zhou, Li-Gang., Hao, Xiao-Jiang. Alkaloids from Anabasis aphylla L.. journal of asian natural products research, 2008, vol. 10, no. 11, p. 1093–1095. DOI: 10.1080/10286020802318966. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

N-methylanabasine (RF-00003512-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

N-methylanabasine (RF-00003512-PAR) in aerial parts

Composition #10: Du, Hua., Wang, Ye., Yan, Chen., Zhou, Li-Gang., Hao, Xiao-Jiang. Alkaloids from Anabasis aphylla L.. journal of asian natural products research, 2008, vol. 10, no. 11, p. 1093–1095. DOI: 10.1080/10286020802318966. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

anabasamine (RF-00004142-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

anabasamine (RF-00004142-PAR) in aerial parts

Composition #11: Du, Hua., Wang, Ye., Yan, Chen., Zhou, Li-Gang., Hao, Xiao-Jiang. Alkaloids from Anabasis aphylla L.. journal of asian natural products research, 2008, vol. 10, no. 11, p. 1093–1095. DOI: 10.1080/10286020802318966. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

isonicoteine (RF-00003449-PAR)
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

isonicoteine (RF-00003449-PAR) in aerial parts