Draft - work in progress
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- Albizia lebbeck (L.) Benth.
Albizia lebbeck (L.) Benth.
- Family:
- Fabaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 954
- Number of processed references:
- 9
Composition #1: Yadav, Shyamlal Singh., Galib., Prajapati, Pradeep Kumar., Rudrappa, Harisha C. Pharmacognostical and physicochemical investigations of Albizia lebbeck benth. leaf. international journal of science innovations and discoveries, 2011, vol. 1, no. 2, p. 178–185. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Phloroglucinol+Conc Hcl
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Substance:
Calcium oxalate (RF-00003960-PAR)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Phloroglucinol+Conc Hcl reagent
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
calcium oxalate crystals - leaves
Composition #2: Yadav, Shyamlal Singh., Galib., Prajapati, Pradeep Kumar., Rudrappa, Harisha C. Pharmacognostical and physicochemical investigations of Albizia lebbeck benth. leaf. international journal of science innovations and discoveries, 2011, vol. 1, no. 2, p. 178–185. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol extract
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Substance:
Epicatechin-3-gallate (RF-00010397-PAR)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Dil. FeCl3
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.0098
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Internal remarks:
epicatechin gallate 0.0098% w/w in leaves
Composition #3: Yadav, Shyamlal Singh., Galib., Prajapati, Pradeep Kumar., Rudrappa, Harisha C. Pharmacognostical and physicochemical investigations of Albizia lebbeck benth. leaf. international journal of science innovations and discoveries, 2011, vol. 1, no. 2, p. 178–185. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol extract
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Dragendorff’s reagent
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloid - leaves
Composition #4: Yadav, Shyamlal Singh., Galib., Prajapati, Pradeep Kumar., Rudrappa, Harisha C. Pharmacognostical and physicochemical investigations of Albizia lebbeck benth. leaf. international journal of science innovations and discoveries, 2011, vol. 1, no. 2, p. 178–185. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol extract
-
Substance:
Tannins (RF-00004337-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Analytical method - additional description:
Dil. FeCl3
-
Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
tannins - leaves
Composition #5: Yadav, Shyamlal Singh., Galib., Prajapati, Pradeep Kumar., Rudrappa, Harisha C. Pharmacognostical and physicochemical investigations of Albizia lebbeck benth. leaf. international journal of science innovations and discoveries, 2011, vol. 1, no. 2, p. 178–185. .
-
-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
ethanol extract
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Substance:
epigallocatechin gallate (RF-00003802-PAR)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Dil. FeCl3
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Result unit:
Percent (G138A)
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Result type:
Numerical Value (VAL)
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Value (concentration, content):
0.0183
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Internal remarks:
Epigallocatechine gallate 0.0183% w/w in leaves
Composition #6: Bobby, M. D. Nazneen., Wesely, E. G., Johnson, M. High performance thin layer chromatography profile studies on the alkaloids of Albizia lebbeck . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 1, p. S1–S6. .
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
petroleum ether, ethylacetate, methanolic extract
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
alkaloids in fresh leaves
Composition #7: Bobby, M. D. Nazneen., Wesely, E. G., Johnson, M. High performance thin layer chromatography profile studies on the alkaloids of Albizia lebbeck . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 1, p. S1–S6. .
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-
Plant part:
Leaves (as part-nature) (A0EKT)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
petroleum ether, ethylacetate, methanolic extract
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins in fresh leaves
Composition #8: Kumar, D., Dash, G.K., Tripathy, N.K. Hypoglycaemic activity of bark extracts of Albizia lebbeck benth. in streptozotocin induced diabetic rats. international journal of pharmaceutical sciences review and research, 2013, vol. 18, no. 2, p. 28–32. .
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Plant part:
Bark (as part-nature) (A066X)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Tannins (RF-00004337-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
tannins - bark
Composition #9: Kumar, D., Dash, G.K., Tripathy, N.K. Hypoglycaemic activity of bark extracts of Albizia lebbeck benth. in streptozotocin induced diabetic rats. international journal of pharmaceutical sciences review and research, 2013, vol. 18, no. 2, p. 28–32. .
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Plant part:
Bark (as part-nature) (A066X)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
Saponins (RF-00004333-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
saponins - bark
Composition #10: Scott, Janelle P., Tinto, Winston F., Reynolds, William F. Triterpenoidal Saponins and Prosapogenins from Albizia lebbeck (Leguminosae) . natural product communications, 2008, vol. 3, no. 11, p. 1763–1770. .
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol
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Substance:
Triterpene saponins Triterpene saponins (RF-00004338-PAR)
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Additional substance description:
prosapogenins, echinocystic acid glycosides
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
triterpene saponins - seed
Composition #11: Note, Olivier Placide., Jihu, Dong., Antheaume, Cyril., Zeniou, Maria., Pegnyemb, Dieudonne Emmanuel., Guillaume, Dominique., Chneiwess, Herve., Kilhoffer, Marie Claude., Lobstein, Annelise. Triterpenoid saponins from Albizia lebbeck (L.) Benth and their inhibitory effect on the survival of high grade human brain tumor cells . carbohydrate research, 2015, vol. 404, p. 26–33. DOI: 10.1016/j.carres.2014.12.004.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol extract
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Substance:
Triterpene saponins Triterpene saponins (RF-00004338-PAR)
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Additional substance description:
lebbeckosides A–B
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Analytical method code:
Nuclear Magnetic Resonance (NMR) (F061A)
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
root - lebbeckosides A–B
Composition #12: Amog, P. U., Manjuprasanna, V. N., Yariswamy, M., Urs, A. N. Nanjaraj., Joshi, Vikram., Suvilesh, K. N., Nataraju, A., Vishwanath, Bannikuppe Sannanaik., Gowda, T. V. Albizia lebbeck seed methanolic extract as a complementary therapy to manage local toxicity of Echis carinatus venom in a murine model . pharmaceutical biology, 2016, vol. 54, no. 11, p. 2568–2574. DOI: 10.3109/13880209.2016.1171882.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
chloroform and methanol extract
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Substance:
Alkaloids (RF-00004360-PAR)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Nanjaraj Urs et al. 2015
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
alkaloids in seed
Composition #13: Amog, P. U., Manjuprasanna, V. N., Yariswamy, M., Urs, A. N. Nanjaraj., Joshi, Vikram., Suvilesh, K. N., Nataraju, A., Vishwanath, Bannikuppe Sannanaik., Gowda, T. V. Albizia lebbeck seed methanolic extract as a complementary therapy to manage local toxicity of Echis carinatus venom in a murine model . pharmaceutical biology, 2016, vol. 54, no. 11, p. 2568–2574. DOI: 10.3109/13880209.2016.1171882.
[
DOI link]
-
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
methanol extract
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Substance:
Anthraquinone (RF-0475-001-PPP)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Nanjaraj Urs et al. 2015
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
anthraquinones in seed
Composition #14: Amog, P. U., Manjuprasanna, V. N., Yariswamy, M., Urs, A. N. Nanjaraj., Joshi, Vikram., Suvilesh, K. N., Nataraju, A., Vishwanath, Bannikuppe Sannanaik., Gowda, T. V. Albizia lebbeck seed methanolic extract as a complementary therapy to manage local toxicity of Echis carinatus venom in a murine model . pharmaceutical biology, 2016, vol. 54, no. 11, p. 2568–2574. DOI: 10.3109/13880209.2016.1171882.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
water and methanol extract
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Substance:
Phenolic compounds Phenolic compounds (RF-00000010-ORG)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Nanjaraj Urs et al. 2015
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
phenolics in seed
Composition #15: Amog, P. U., Manjuprasanna, V. N., Yariswamy, M., Urs, A. N. Nanjaraj., Joshi, Vikram., Suvilesh, K. N., Nataraju, A., Vishwanath, Bannikuppe Sannanaik., Gowda, T. V. Albizia lebbeck seed methanolic extract as a complementary therapy to manage local toxicity of Echis carinatus venom in a murine model . pharmaceutical biology, 2016, vol. 54, no. 11, p. 2568–2574. DOI: 10.3109/13880209.2016.1171882.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
chloroform and methanol extract
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Substance:
Steroids (RF-00000309-VET)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Nanjaraj Urs et al. 2015
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
steroids in seed
Composition #16: Amog, P. U., Manjuprasanna, V. N., Yariswamy, M., Urs, A. N. Nanjaraj., Joshi, Vikram., Suvilesh, K. N., Nataraju, A., Vishwanath, Bannikuppe Sannanaik., Gowda, T. V. Albizia lebbeck seed methanolic extract as a complementary therapy to manage local toxicity of Echis carinatus venom in a murine model . pharmaceutical biology, 2016, vol. 54, no. 11, p. 2568–2574. DOI: 10.3109/13880209.2016.1171882.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Additional extraction description:
water and methanol extract
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Analytical method - additional description:
Nanjaraj Urs et al. 2015
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins in seed
Composition #17: SOTELO, A., CONTRERAS, E., FLORES, S. NUTRITIONAL-VALUE AND CONTENT OF ANTINUTRITIONAL COMPOUNDS AND TOXICS IN 10 WILD LEGUMES OF YUCATAN PENINSULA . plant foods for human nutrition, 1995, vol. 47, no. 2, p. 115–123. DOI: 10.1007/BF01089260.
[
DOI link]
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Plant part:
Seed (as part-nature) (A066P)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
0.85% NaCl
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Substance:
Lectins (RF-00000439-ORG)
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Analytical method code:
Unspecified (F598A)
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Analytical method - additional description:
Jaffe et al
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
lectins - seed
Composition #18: SOTELO, A., CONTRERAS, E., FLORES, S. NUTRITIONAL-VALUE AND CONTENT OF ANTINUTRITIONAL COMPOUNDS AND TOXICS IN 10 WILD LEGUMES OF YUCATAN PENINSULA . plant foods for human nutrition, 1995, vol. 47, no. 2, p. 115–123. DOI: 10.1007/BF01089260.
[
DOI link]
-
-
Plant part:
Seed (as part-nature) (A066P)
-
Extraction/Preparation method:
Solvent extraction (A0BZR)
-
Substance:
Saponins (RF-00004333-PAR)
-
Analytical method code:
Unspecified (F598A)
-
Analytical method - additional description:
hemaglutinnins detection
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Yes/No Qualitative:
Positive/Present (POS)
-
Result type:
Qualitative Value (Binary) (BIN)
-
Internal remarks:
saponins - seed
Endpoint study
#1: Olorunsanya, A.O., Egbewande, O.O., Ibrahim, H., Adeyemo, M.M. Growth performance and carcass analysis of broiler chickens fed graded levels of toasted Albizia lebbeck seed meal. pakistan journal of nutrition, 2010, vol. 9, no. 9, p. 873–876. .
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Study relevance:
Animal (target species) health
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Plant part:
Seed (as part-nature) (A066P)
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Type of toxicological test:
subchronic (CHD013TT)
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Tested organism:
Gallus gallus (chicken) (as animal) (A057Z)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Unit of exposure duration:
Week (G205A)
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Number of organisms dosed:
10
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Percent (G138A)
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Effect concentration:
5-20
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Critical effect:
Digestive (TOX18A)
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Target tissue:
Digestive (TT002A)
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Effect description:
reduced feed intake, affected overall performance, carcass characteristics and mortality in doses higher above 5%
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
broliers 5-20% of seed in feed, toxic effect and mortality
Endpoint study
#2: GALAL, M., BASHIR, AK., SALIH, AM., ADAM, SEI. ACTIVITY OF WATER EXTRACTS OF ALBIZZIA-ANTHELMINTICA AND A-LEBBEK BARKS AGAINST EXPERIMENTAL HYMENOLEPIS-DIMINUTA INFECTION IN RATS . journal of ethnopharmacology, 1991, vol. 31, no. 3, p. 333–337. DOI: 10.1016/0378-8741(91)90019-A.
[
DOI link]
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Study relevance:
Human health
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Plant part:
Bark (as part-nature) (A066X)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
water extract
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Type of toxicological test:
acute toxicity (CHD016TT)
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Tested organism:
Rat (as animal) (A0CNV)
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Route of exposure:
ORAL: UNSPECIFIED (OECD2234PL)
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Unit of exposure duration:
Day (G134A)
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Number of organisms dosed:
5
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Endpoint measured:
Dose level (CHD014EP)
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Concentration unit:
Gram/kilogram (G015A)
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Effect concentration:
150
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Effect description:
lethal
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
lethal - bark - 150g/kg