EFSA
ecomole
vscht
  2. Ageratina altissima (L.) R.M.King & H.Rob. // Eupatorium rugosum Houtt.

Ageratina altissima (L.) R.M.King & H.Rob. // Eupatorium rugosum Houtt.

Family:
Asteraceae
Approval state:
Approved
Number of articles retrieved:
136
Number of processed references:
6
Compositions
#1: 3-oxyangeloyl-tremetone in aerial parts. #2: dehydrotremetone in aerial parts. #3: tremetone in aerial parts. #4: tremetone and dehydrotremetone #5: tremetone in aerial parts #6: dehydrotremetone in aerial parts #7: 6-hydroxytremetone in aerial parts #8: benzofuran ketones in aerial parts
Endpoint Studies
#1: Goat: Depression, anorexia, no trembles #2: Horse: Unsteady gait, difficulty in swallowing, acetone breath, cardiac arrhythmias, constipation, trembling of muscles #3: Sheep: Trembles, anorexia, laboured respiration stiffness of limbs, ataxia #4: Cattle: Trembles, acetone breath,constipation, difficult respiration,profuse nasal discharge #5: Chicken: Trembles, cyanosis, severe acidosis #6: Tremetone toxicity in horses - increased CK, AST; muscle necrosis; myocardial necrosis #7: Skeletal muscular effects (weight loss, excessive salivation, dyspnea, severe skeletal muscle necrosis, trembling; the death of cardiotoxic effects) in cow linked to toxic effect of tremetone and dehydrotremetone #8: tremetone toxicity stable after drying causing degeneration and necrosis of skeletal muscle. #9: muscle degeneration and necrosis #10: differences in CK, AST, ALT, LDH;
Genotoxicity
Composition #1: Lee, Stephen T., Davis, T. Zane., Gardner, Dale R., Stegelmeier, Bryan L., Evans, Tim J. Quantitative Method for the Measurement of Three Benzofuran Ketones in Rayless Goldenrod (Isocoma pluriflora) and White Snakeroot (Ageratina altissima) by High-Performance Liquid Chromatography (HPLC) . journal of agricultural and food chemistry, 2009, vol. 57, no. 12, p. 5639–5643. DOI: 10.1021/jf900781j. [DOI link]
Composition #2: Lee, Stephen T., Davis, T. Zane., Gardner, Dale R., Stegelmeier, Bryan L., Evans, Tim J. Quantitative Method for the Measurement of Three Benzofuran Ketones in Rayless Goldenrod (Isocoma pluriflora) and White Snakeroot (Ageratina altissima) by High-Performance Liquid Chromatography (HPLC) . journal of agricultural and food chemistry, 2009, vol. 57, no. 12, p. 5639–5643. DOI: 10.1021/jf900781j. [DOI link]
Composition #3: Lee, Stephen T., Davis, T. Zane., Gardner, Dale R., Stegelmeier, Bryan L., Evans, Tim J. Quantitative Method for the Measurement of Three Benzofuran Ketones in Rayless Goldenrod (Isocoma pluriflora) and White Snakeroot (Ageratina altissima) by High-Performance Liquid Chromatography (HPLC) . journal of agricultural and food chemistry, 2009, vol. 57, no. 12, p. 5639–5643. DOI: 10.1021/jf900781j. [DOI link]
Composition #4: Meyerholtz, Kimberly A., Burcham, Grant N., Miller, Margaret A., Wilson, Christina R., Hooser, Stephen B., Lee, Stephen T. Development of a gas chromatography-mass spectrometry technique to diagnose white snakeroot (Ageratina altissima) poisoning in a cow . journal of veterinary diagnostic investigation, 2011, vol. 23, no. 4, p. 775–779. DOI: 10.1177/1040638711407899. [DOI link]
Composition #5: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]
Composition #6: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]
Composition #7: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]
Composition #8: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]
Endpoint study #1: Sharma, Om P., Dawra, Rajinder K., Kurade, Nitin P., Sharma, Pritam D. A review of the toxicosis and biological properties of the genus Eupatorium . natural toxins, 1998, vol. 6, no. 1, p. 1–14. .
Endpoint study #2: Sharma, Om P., Dawra, Rajinder K., Kurade, Nitin P., Sharma, Pritam D. A review of the toxicosis and biological properties of the genus Eupatorium . natural toxins, 1998, vol. 6, no. 1, p. 1–14. .
Endpoint study #3: Sharma, Om P., Dawra, Rajinder K., Kurade, Nitin P., Sharma, Pritam D. A review of the toxicosis and biological properties of the genus Eupatorium . natural toxins, 1998, vol. 6, no. 1, p. 1–14. .
Endpoint study #4: Sharma, Om P., Dawra, Rajinder K., Kurade, Nitin P., Sharma, Pritam D. A review of the toxicosis and biological properties of the genus Eupatorium . natural toxins, 1998, vol. 6, no. 1, p. 1–14. .
Endpoint study #5: Sharma, Om P., Dawra, Rajinder K., Kurade, Nitin P., Sharma, Pritam D. A review of the toxicosis and biological properties of the genus Eupatorium . natural toxins, 1998, vol. 6, no. 1, p. 1–14. .
Endpoint study #6: Finno, Carrie J., Valberg, Stephanie J., Wunschmann, Arno., Murphy, Michael J. Seasonal pasture myopathy in horses in the midwestern United States: 14 cases (1998-2005) . javma-journal of the american veterinary medical association, 2006, vol. 229, no. 7, p. 1134–1141. DOI: 10.2460/javma.229.7.1134. [DOI link]
Endpoint study #7: Meyerholtz, Kimberly A., Burcham, Grant N., Miller, Margaret A., Wilson, Christina R., Hooser, Stephen B., Lee, Stephen T. Development of a gas chromatography-mass spectrometry technique to diagnose white snakeroot (Ageratina altissima) poisoning in a cow . journal of veterinary diagnostic investigation, 2011, vol. 23, no. 4, p. 775–779. DOI: 10.1177/1040638711407899. [DOI link]
Endpoint study #8: Lee, Stephen T., Davis, T. Zane., Cook, Daniel., Stegelmeier, Bryan L. Evaluation of Drying Methods and Toxicity of Rayless Goldenrod (Isocoma pluriflora) and White Snakeroot (Ageratina altissima) in Goats . journal of agricultural and food chemistry, 2012, vol. 60, no. 19, p. 4849–4853. DOI: 10.1021/jf300829v. [DOI link]
Endpoint study #9: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]
Endpoint study #10: Davis, T. Z., Stegelmeier, B. L., Lee, S. T., Collett, M. G., Green, B. T., Pfister, J. A., Evans, T. J., Grum, D. S., Buck, S. White snakeroot poisoning in goats: Variations in toxicity with different plant chemotypes . research in veterinary science, 2016, vol. 106, p. 29–36. DOI: 10.1016/j.rvsc.2016.02.008. [DOI link]