EFSA Compendium of Botanicals

Draft - work in progress

Agathosma crenulata (L.) Pillians (as plant) // Agathosma crenulata (L.) Pillans // Barosma crenulata (L.) Hook.

Family:: Rutaceae
Approval state:: Approved
Number of articles retrieved:: 27
Number of processed references:: 3

Compositions

#1: 8-hydroxymenthone #2: myrcene #3: trans-isopulegone #4: trans-8-acetylthio-p-menthan-3-one #5: Pulegone #6: cis-isopulegone #7: isomenthone #8: 1,8-cineole #9: Menthone #10: 3-Oxo-p-menthane-8-thiol acetate #11: pulegone in aerial parts #12: cis-isopulegone in aerial parts #13: menthone in aerial parts #14: isomenthone in aerial parts #15: trans-isopulegone in aerial parts

Endpoint Studies

Genotoxicity

Composition #1: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

monoterpene ketones (RF-00010825-PAR)
Additional substance description:

8-hydroxymenthone
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.67
Internal remarks:

8-hydroxymenthone

Composition #2: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.01
Internal remarks:

myrcene

Composition #3: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

trans-isopulegone (RF-00004088-PAR)
Additional substance description:

pulegone
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.77
Internal remarks:

trans-isopulegone

Composition #4: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

monoterpene ketones (RF-00010825-PAR)
Additional substance description:

trans-8-acetylthio-p-menthan-3-one
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.83
Internal remarks:

trans-8-acetylthio-p-menthan-3-one

Composition #5: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(+)-pulegone (RF-00003398-PAR)
Additional substance description:

pulegone
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

53.75
Internal remarks:

Pulegone

Composition #6: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

cis-isopulegone (RF-00003746-PAR)
Additional substance description:

pulegone
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.78
Internal remarks:

cis-isopulegone

Composition #7: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

d,l-Isomenthone (RF-00010214-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.58
Internal remarks:

isomenthone

Composition #8: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.19
Internal remarks:

1,8-cineole

Composition #9: Posthumus, M.A., van Beek, T.A., Collins, N.F., Graven, E.H. Chemical composition of the essential oils of agathosma betulina, A. Crenulata and an A. Betulina x crenulata Hybrid (buchu). journal of essential oil research, 1996, vol. 8, no. 3, p. 223–228. DOI: 10.1080/10412905.1996.9700606. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

menthone (RF-00011280-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

GC-FID
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.91
Internal remarks:

Menthone

Composition #10: Koepke, Thomas., Schmarr, Hans-Georg., Mosandl, Armin. Stereoisomeric Flavour Compounds. Part LVII: The Stereoisomers of 3-Oxo-p-menthane-8-thiol acetate, Simultaneously Stereoanalysed with their Corresponding Thiols . flavour and fragrance journal, 1992, vol. 7, no. 4, p. 205–211. DOI: 10.1002/ffj.2730070407. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

monoterpene ketones (RF-00010825-PAR)
Additional substance description:

3-Oxo-p-menthane-8-thiol acetate
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

Hearth-cut-GC-GC, GC-FID
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

3-Oxo-p-menthane-8-thiol acetate

Composition #11: Sandasi, M., Kamatou, G. P. P., Baranska, M., Viljoen, A. M. Application of vibrational spectroscopy in the quality assessment of Buchu oil obtained from two commercially important Agathosma species (Rutaceae) . south african journal of botany, 2010, vol. 76, no. 4, p. 692–700. DOI: 10.1016/j.sajb.2010.07.013. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(+)-pulegone (RF-00003398-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

spectroscopy
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

50-66
Internal remarks:

pulegone in aerial parts

Composition #12: Sandasi, M., Kamatou, G. P. P., Baranska, M., Viljoen, A. M. Application of vibrational spectroscopy in the quality assessment of Buchu oil obtained from two commercially important Agathosma species (Rutaceae) . south african journal of botany, 2010, vol. 76, no. 4, p. 692–700. DOI: 10.1016/j.sajb.2010.07.013. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

cis-isopulegone (RF-00003746-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

spectroscopy
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.7-5
Internal remarks:

cis-isopulegone in aerial parts

Composition #13: Sandasi, M., Kamatou, G. P. P., Baranska, M., Viljoen, A. M. Application of vibrational spectroscopy in the quality assessment of Buchu oil obtained from two commercially important Agathosma species (Rutaceae) . south african journal of botany, 2010, vol. 76, no. 4, p. 692–700. DOI: 10.1016/j.sajb.2010.07.013. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

menthone (RF-00011280-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

spectroscopy
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1-4
Internal remarks:

menthone in aerial parts

Composition #14: Sandasi, M., Kamatou, G. P. P., Baranska, M., Viljoen, A. M. Application of vibrational spectroscopy in the quality assessment of Buchu oil obtained from two commercially important Agathosma species (Rutaceae) . south african journal of botany, 2010, vol. 76, no. 4, p. 692–700. DOI: 10.1016/j.sajb.2010.07.013. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

d,l-Isomenthone (RF-00010214-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

spectroscopy
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6-15
Internal remarks:

isomenthone in aerial parts

Composition #15: Sandasi, M., Kamatou, G. P. P., Baranska, M., Viljoen, A. M. Application of vibrational spectroscopy in the quality assessment of Buchu oil obtained from two commercially important Agathosma species (Rutaceae) . south african journal of botany, 2010, vol. 76, no. 4, p. 692–700. DOI: 10.1016/j.sajb.2010.07.013. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

trans-isopulegone (RF-00004088-PAR)
Analytical method code:

GC-MS (F046A)
Analytical method - additional description:

spectroscopy
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.1-3.9
Internal remarks:

trans-isopulegone in aerial parts