EFSA Compendium of Botanicals

Draft - work in progress

Adonis vernalis L.

Family:: Ranunculaceae
Approval state:: Approved
Number of articles retrieved:: 346
Number of processed references:: 3

Compositions

#1: adonitoxin (RF-00003666-PAR) #2: adonitoxol #3: cymarin (RF-00003761-PAR #4: K-strofantin #5: strofantidin #6: cymarin #7: adonitoxin #8: k-strophantidin #9: magnoflorine (RF-00003919-PAR) #10: Corytuberine (cx000107)

Endpoint Studies

Genotoxicity

Composition #1: Cserep, A., Masler, L., Sikl, D., Bauer, S. Adonitoxol, a new cardiac glycoside of Adonis vernalis.. chemicke zvesti, 1964, vol. 18, p. 273–80. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

adonitoxin (RF-00003666-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

adonitoxin (RF-00003666-PAR)

Composition #2: Cserep, A., Masler, L., Sikl, D., Bauer, S. Adonitoxol, a new cardiac glycoside of Adonis vernalis.. chemicke zvesti, 1964, vol. 18, p. 273–80. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

ethanol extraction
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

adonitoxol
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

adonitoxol

Composition #3: Cserep, A., Masler, L., Sikl, D., Bauer, S. Adonitoxol, a new cardiac glycoside of Adonis vernalis.. chemicke zvesti, 1964, vol. 18, p. 273–80. .

Language:

English (en)
Substance:

cymarin (RF-00003761-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cymarin (RF-00003761-PAR

Composition #4: Cserep, A., Masler, L., Sikl, D., Bauer, S. Adonitoxol, a new cardiac glycoside of Adonis vernalis.. chemicke zvesti, 1964, vol. 18, p. 273–80. .

Language:

English (en)
Substance:

cardiac glycosides (RF-00010823-PAR)
Additional substance description:

"K-strofantin" (Strophanthin K)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

K-strofantin

Composition #5: Cserep, A., Masler, L., Sikl, D., Bauer, S. Adonitoxol, a new cardiac glycoside of Adonis vernalis.. chemicke zvesti, 1964, vol. 18, p. 273–80. .

Language:

English (en)
Substance:

strophantidin (RF-00004065-PAR)
Additional substance description:

strofantidin
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

strofantidin

Composition #6: Goryaev, M. I., Murzagulova, Z. G., Yurina, R. A., Shishkina, N. V. Chemical composition of Adonis vernalis and Adonis wolgensis.. izvestiya akademii nauk kazakhskoi ssr, seriya khimicheskaya, 1971, vol. 21, no. 6, p. 31–5. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

cymarin (RF-00003761-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cymarin

Composition #7: Goryaev, M. I., Murzagulova, Z. G., Yurina, R. A., Shishkina, N. V. Chemical composition of Adonis vernalis and Adonis wolgensis.. izvestiya akademii nauk kazakhskoi ssr, seriya khimicheskaya, 1971, vol. 21, no. 6, p. 31–5. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Substance:

adonitoxin (RF-00003666-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

adonitoxin

Composition #8: Goryaev, M. I., Murzagulova, Z. G., Yurina, R. A., Shishkina, N. V. Chemical composition of Adonis vernalis and Adonis wolgensis.. izvestiya akademii nauk kazakhskoi ssr, seriya khimicheskaya, 1971, vol. 21, no. 6, p. 31–5. .

Language:

English (en)
Plant part:

Unspecified (A07XD)
Substance:

K-strophanthidin (RF-00003466-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

k-strophantidin

Composition #9: Slavik, Jiri., Bochorakova, Jitka., Slavikova, Leonora. Occurrence of magnoflorine and corytuberine in some wild or cultivated plants of Czechoslovakia.. collection of czechoslovak chemical communications, 1987, vol. 52, no. 3, p. 804–11. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

iodide fraction
Substance:

magnoflorine (RF-00003919-PAR)
Analytical method code:

Chromatographic tests (F015A)
Result unit:

Gram (G148A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.86
Internal remarks:

magnoflorine (RF-00003919-PAR)

Composition #10: Slavik, Jiri., Bochorakova, Jitka., Slavikova, Leonora. Occurrence of magnoflorine and corytuberine in some wild or cultivated plants of Czechoslovakia.. collection of czechoslovak chemical communications, 1987, vol. 52, no. 3, p. 804–11. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

iodide fraction
Substance:

Corytuberine (RF-00011231-PAR)
Analytical method code:

Chromatographic tests (F015A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Corytuberine (cx000107)