EFSA
ecomole
vscht
  2. Adenium obesum (Forssk.) Roem. & Schult.

Adenium obesum (Forssk.) Roem. & Schult.

Family:
Apocynaceae
Approval state:
Approved
Number of articles retrieved:
124
Number of processed references:
7
Compositions
#1: Cardiac glycosides were detected in leaves through HPLC and NMR. #2: Isoquercitrin (0.26 mg/g) in leaves through HPLC #3: alkaloids in fruit NMR #4: cardiac glycosides in fruit NMR #5: 16-anhydro-3acetyl-gitoxigenin detected in root #6: 16-anhydro-3acetyl-gitoxigenin detected in stem #7: saponins in bark #8: pregnanes in stems NMR #9: pregnanes in roots NMR #10: cardiac glycosides roots NMR #11: cardiac glycosides stems NMR
Endpoint Studies
#1: The LD50 values within 24 h were found to be 9.69 and 22.10 g plant/ kg body weight, for CH2Cl2 and H2O extracts of the root, respectively.
Genotoxicity
Composition #1: Arai, Midori A., Tateno, Chikashi., Koyano, Takashi., Kowithayakorn, Thaworn., Kawabe, Seiichiro., Ishibashi, Masami. New hedgehog/GLI-signaling inhibitors from Adenium obesum. organic & biomolecular chemistry, 2011, vol. 9, no. 4, p. 1133–1139. DOI: 10.1039/c0ob00677g. [DOI link]
Composition #2: Meda, N. R., Fraisse, D., Gnoula, C., Peyrode, C., Texier, O., Senejoux, F., Felgines, C. Characterization and Quantification of Polyphenolic Compounds from Adenium Obesum Leaves . chemistry of natural compounds, 2016, vol. 52, no. 1, p. 134–135. DOI: 10.1007/s10600-016-1570-2. [DOI link]
Composition #3: Ahmed, Salman Khalid., Versiani, Muhammad Ali., Ikram, Ambreen., Sattar, Samina Abdul., Faizi, Shaheen. Cytotoxic cardiac glycosides from the fruit (pods) of Adenium obesum (Forssk.) Roem. & Schult . natural product research, 2017, vol. 31, no. 10, p. 1205–1208. DOI: 10.1080/14786419.2016.1226826. [DOI link]
Composition #4: Ahmed, Salman Khalid., Versiani, Muhammad Ali., Ikram, Ambreen., Sattar, Samina Abdul., Faizi, Shaheen. Cytotoxic cardiac glycosides from the fruit (pods) of Adenium obesum (Forssk.) Roem. & Schult . natural product research, 2017, vol. 31, no. 10, p. 1205–1208. DOI: 10.1080/14786419.2016.1226826. [DOI link]
Composition #5: VETHAVIYASAR, N., JOHN, D. 16-ANHYDRO-3-ACETYL-GITOXIGENIN IN ADENIUM-OBESUM. planta medica, 1982, vol. 44, no. 2, p. 123–124. DOI: 10.1055/s-2007-971419. [DOI link]
Composition #6: VETHAVIYASAR, N., JOHN, D. 16-ANHYDRO-3-ACETYL-GITOXIGENIN IN ADENIUM-OBESUM. planta medica, 1982, vol. 44, no. 2, p. 123–124. DOI: 10.1055/s-2007-971419. [DOI link]
Composition #7: ALYAHYA, MA., MOSSA, JS., TARIQ, M., ALMESHAL, IA., ALBADR, AA. PHYTOTOXICITY STUDIES ON SAUDI PLANTS. toxicon, 1987, vol. 25, no. 4, p. 363–364. .
Composition #8: YAMAUCHI, T., ABE, F. CARDIAC-GLYCOSIDES AND PREGNANES FROM ADENIUM-OBESUM (STUDIES ON THE CONSTITUENTS OF ADENIUM .1.) . chemical & pharmaceutical bulletin, 1990, vol. 38, no. 3, p. 669–672. .
Composition #9: YAMAUCHI, T., ABE, F. CARDIAC-GLYCOSIDES AND PREGNANES FROM ADENIUM-OBESUM (STUDIES ON THE CONSTITUENTS OF ADENIUM .1.) . chemical & pharmaceutical bulletin, 1990, vol. 38, no. 3, p. 669–672. .
Composition #10: YAMAUCHI, T., ABE, F. CARDIAC-GLYCOSIDES AND PREGNANES FROM ADENIUM-OBESUM (STUDIES ON THE CONSTITUENTS OF ADENIUM .1.) . chemical & pharmaceutical bulletin, 1990, vol. 38, no. 3, p. 669–672. .
Composition #11: YAMAUCHI, T., ABE, F. CARDIAC-GLYCOSIDES AND PREGNANES FROM ADENIUM-OBESUM (STUDIES ON THE CONSTITUENTS OF ADENIUM .1.) . chemical & pharmaceutical bulletin, 1990, vol. 38, no. 3, p. 669–672. .
Endpoint study #1: Versiani, Muhammad Ali., Ahmed, Salman Khalid., Ikram, Ambreen., Ali, Syed Tahir., Yasmeen, Kousar., Faizi, Shaheen. Chemical Constituents and Biological Activities of Adenium obesum (Forsk.) Roem. et Schult. . chemistry & biodiversity, 2014, vol. 11, no. 2, p. 171–180. DOI: 10.1002/cbdv.201200254. [DOI link]