EFSA Compendium of Botanicals

Draft - work in progress

Actaea spicata L.

Family:: Ranunculaceae
Approval state:: Approved
Number of articles retrieved:: 79
Number of processed references:: 2

Compositions

#1: Tannins #2: Calcium oxalate #3: Alkaloids #4: Magnoflorine in roots and aerial parts #5: Corytuberine in roots and aerial parts.

Endpoint Studies

Genotoxicity

Composition #1: Madaan, Reecha., Bansal, Gundeep., Sharma, Anupam. Pharmacognostic standardization of Actaea spicata.. journal of pharmaceutical and biomedical sciences, 2011, p. 10. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water and methanol
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Phytochemical screening (F604A)
Analytical method - additional description:

TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #2: Madaan, Reecha., Bansal, Gundeep., Sharma, Anupam. Pharmacognostic standardization of Actaea spicata.. journal of pharmaceutical and biomedical sciences, 2011, p. 10. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Drying (dehydration) (A07KG)
Additional extraction description:

microscopy
Substance:

Calcium oxalate (RF-00003960-PAR)
Analytical method code:

Microscopic detection (F536A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Calcium oxalate

Composition #3: Madaan, Reecha., Bansal, Gundeep., Sharma, Anupam. Pharmacognostic standardization of Actaea spicata.. journal of pharmaceutical and biomedical sciences, 2011, p. 10. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

chloroform and methanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method code:

Phytochemical screening (F604A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids

Composition #4: SLAVIK, J., SLAVIKOVA, L. QUATERNARY ISOQUINOLINE ALKALOIDS AND SOME DITERPENOID ALKALOIDS IN PLANTS OF THE CZECH-REPUBLIC . collection of czechoslovak chemical communications, 1995, vol. 60, no. 6, p. 1034–1041. DOI: 10.1135/cccc19951034. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

magnoflorine (RF-00003919-PAR)
Additional substance description:

small quantity
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Analytical method - additional description:

IR,MS,TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Magnoflorine in roots and aerial parts

Composition #5: SLAVIK, J., SLAVIKOVA, L. QUATERNARY ISOQUINOLINE ALKALOIDS AND SOME DITERPENOID ALKALOIDS IN PLANTS OF THE CZECH-REPUBLIC . collection of czechoslovak chemical communications, 1995, vol. 60, no. 6, p. 1034–1041. DOI: 10.1135/cccc19951034. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Corytuberine (RF-00011231-PAR)
Additional substance description:

traces
Analytical method code:

UV/VIS spectroscopy (photometry) (F009A)
Analytical method - additional description:

IR,MS,TLC
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Corytuberine in roots and aerial parts.