Calamus (as plant) // Acorus calamus L.

Family:
Acoraceae
Approval state:
Approved
Number of articles retrieved:
3253
Number of processed references:
8
Compositions
#1: alkaloids (Fresh rhizome) #2: Tannins (Fresh rhizome) #3: saponins (Fresh rhizome) #4: Saponins (Roots) #5: Tannins (Roots) #6: #7: alpha-asarone (volatile oil) #8: beta-asarone (volatile oil)
Endpoint Studies
#1: #2: tremors, piloerection and abdominal breathing at LD50 1750 mg/kg body weight
Genotoxicity
#1: #2: DNA strand breaks, induced by a-arason, were to some extent characterized as DNA double strand breaks.
Composition #1: Muthuraman, Arunachalam., Singh, Nirmal. Acute and sub-acute oral toxicity profile of Acorus calamus (Sweet flag) in rodents . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 2, p. S1017–S1023. .
Composition #2: Muthuraman, Arunachalam., Singh, Nirmal. Acute and sub-acute oral toxicity profile of Acorus calamus (Sweet flag) in rodents . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 2, p. S1017–S1023. .
Composition #3: Muthuraman, Arunachalam., Singh, Nirmal. Acute and sub-acute oral toxicity profile of Acorus calamus (Sweet flag) in rodents . asian pacific journal of tropical biomedicine, 2012, vol. 2, no. Suppl. 2, p. S1017–S1023. .
Composition #4: Khan, Mohammad Ahad Ali., Islam, Mohammad Torequl. Analgesic and cytotoxic activity of Acorus calamus L., Kigelia pinnata L., Mangifera indica L. and Tabernaemontana divaricata L. . journal of pharmacy & bioallied sciences, 2012, vol. 4, no. 2, p. 149–54. DOI: 10.4103/0975-7406.94820. [DOI link]
Composition #5: Khan, Mohammad Ahad Ali., Islam, Mohammad Torequl. Analgesic and cytotoxic activity of Acorus calamus L., Kigelia pinnata L., Mangifera indica L. and Tabernaemontana divaricata L. . journal of pharmacy & bioallied sciences, 2012, vol. 4, no. 2, p. 149–54. DOI: 10.4103/0975-7406.94820. [DOI link]
Composition #6: Maurya, Santosh Kumar., Seth, Ankit., Laloo, Damiki., Singh, Narendra Kumar., Gautam, Dev Nath Singh., Singh, Anil Kumar. Sodhana: An Ayurvedic process for detoxification and modification of therapeutic activities of poisonous medicinal plants. . ancient science of life, 2015, vol. 34, no. 4, p. 188–97. DOI: 10.4103/0257-7941.160862. [DOI link]
Composition #7: Berg, Kerstin., Bischoff, Roland., Stegmueller, Simone., Cartus, Alexander., Schrenk, Dieter. Comparative investigation of the mutagenicity of propenylic and allylic asarone isomers in the Ames fluctuation assay . mutagenesis, 2016, vol. 31, no. 4, p. 443–451. DOI: 10.1093/mutage/gew007. [DOI link]
Composition #8: Berg, Kerstin., Bischoff, Roland., Stegmueller, Simone., Cartus, Alexander., Schrenk, Dieter. Comparative investigation of the mutagenicity of propenylic and allylic asarone isomers in the Ames fluctuation assay . mutagenesis, 2016, vol. 31, no. 4, p. 443–451. DOI: 10.1093/mutage/gew007. [DOI link]
Endpoint study #1: Yabiku, Helena Yuco., Oga, Seizi., Lajolo, Franco., Andrighetti, Heloisa. Toxicity of α and β-asarone, and calamus oil for mice and chick embryos, and mutagenicity for Salmonella typhimurium.. revista do instituto adolfo lutz, 1987, vol. 45, no. 1-2, p. 1–12. .
Endpoint study #2: Shah, P., Ghag, M., Deshmukh, P., Kulkarni, Y., Joshi, S., Vyas, B., Shah, D. Toxicity study of ethanolic extract of Acorus calamus rhizome. international journal of green pharmacy, 2012, vol. 6, no. 1, p. 29–35. DOI: 10.4103/0973-8258.97119. [DOI link]
Genotox #1: Jin, Zhongchu., Qin, Wenqing., Chen, Xingruo. Mutagenicity of α-asarone from Acorus calamus and its metabolic pathway in vitro.. zhejiang yike daxue xuebao, 1982, vol. 11, no. 1, p. 1–3, 25. .
Genotox #2: Haupenthal, S., Berg, K., Gruendken, M., Vallicotti, S., Hemgesberg, M., Sak, K., Schrenk, D., Esselen, M. In vitro genotoxicity of carcinogenic asarone isomers. food & function, 2017, vol. 8, no. 3, p. 1227–1234. DOI: 10.1039/c6fo01701k. [DOI link]