Aconitum napellus L.

Family:
Ranunculaceae
Approval state:
Approved
Number of articles retrieved:
394
Number of processed references:
4
Compositions
#1: aconitine #2: Aconitine #3: Diterpene alkaloids #4: lycoctonine
Endpoint Studies
#1: Clinical signs of weakness, ataxia, respiratory distress, and diarrhea were observed. #2: 5 cattle died after ingestion of plant #3: aconitine in roots leading to cardiovascular and neurological symptoms #4: aconitine in flower - death
Genotoxicity
Composition #1: Burmann, J. Annual Variations in the Amount of Active Principles of Certain Medicinal Plants.. zzz, 1911, vol. 49, p. 6–9. .
Composition #2: Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8–10. .
Composition #3: Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8–10. .
Composition #4: Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8–10. .
Endpoint study #1: Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8–10. .
Endpoint study #2: Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8–10. .
Endpoint study #3: Moritz, F., Compagnon, P., Kaliszczak, IG., Kaliszczak, Y., Caliskan, V., Girault, C. Severe acute poisoning with homemade Aconitum napellus capsules: Toxicokinetic and clinical data . clinical toxicology, 2005, vol. 43, no. 7, p. 873–876. DOI: 10.1080/15563650500357594. [DOI link]
Endpoint study #4: Pullela, Ravi., Young, Lorraine., Gallagher, Barry., Avis, Simon P., Randell, Edward W. A case of fatal aconitine poisoning by monkshood ingestion. journal of forensic sciences, 2008, vol. 53, no. 2, p. 491–494. DOI: 10.1111/j.1556-4029.2007.00647.x. [DOI link]