EFSA
ecomole
vscht
  2. Aconitum heterophyllum Wall. ex Royle

Aconitum heterophyllum Wall. ex Royle

Family:
Ranunculaceae
Approval state:
Approved
Number of articles retrieved:
214
Number of processed references:
10
Compositions
#1: hypaconitine in roots #2: aconitine in roots #3: mesaconitine in roots #4: hetisine and heratisine in roots #5: aconitine in rhizomes #6: alkaloids in roots, leaves and stems #7: cardiac glycosides in roots, leaves and stems #8: saponins in roots, leaves and stems #9: tannins and phenolic compounds in roots and leaves #10: atisenol in tuber #11: Atisine in roots #12: Diterpene alkaloids in roots #13: Diterpene Alkaloids in roots #14: total alkaloids in roots
Endpoint Studies
#1: Alpha-glucosidase inhibition
Genotoxicity
Composition #1: Jaiswal, Yogini., Liang, Zhitao., Yong, Peng., Chen, Hubiao., Zhao, Zhongzhen. A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components. . chemistry central journal, 2013, vol. 7, no. 1, p. 169. DOI: 10.1186/1752-153X-7-169. [DOI link]
Composition #2: Jaiswal, Yogini., Liang, Zhitao., Yong, Peng., Chen, Hubiao., Zhao, Zhongzhen. A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components. . chemistry central journal, 2013, vol. 7, no. 1, p. 169. DOI: 10.1186/1752-153X-7-169. [DOI link]
Composition #3: Jaiswal, Yogini., Liang, Zhitao., Yong, Peng., Chen, Hubiao., Zhao, Zhongzhen. A comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components. . chemistry central journal, 2013, vol. 7, no. 1, p. 169. DOI: 10.1186/1752-153X-7-169. [DOI link]
Composition #4: Jacobs, Walter A., Craig, Lyman C. Aconite alkaloids. IX. Isolation of two new alkaloids from Aconitum heterophyllum, heteratisine and hetisine.. journal of biological chemistry, 1942, vol. 143, p. 605–9. .
Composition #5: Jabeen, Neelofar., Shakeel-u-Rehman., Bhat, Khursheed A., Khuroo, Mohd .A., Shawl, Abdul S. Quantitative determination of aconitine in Aconitum chasmanthum and Aconitum heterophyllum from Kashmir Himalayas using HPLC.. journal of pharmacy research, 2011, vol. 4, no. 8, p. 2471–2473. .
Composition #6: Singh, K., Saloni, S., Shalini. Phytochemical screening and TLC profiling of different extracts of leaves, roots and stem of Aconitum Heterophyllum a rare medicinal plant of himalayan region. international journal of pharma and bio sciences, 2015, vol. 6, no. 2, p. P194–P200. .
Composition #7: Singh, K., Saloni, S., Shalini. Phytochemical screening and TLC profiling of different extracts of leaves, roots and stem of Aconitum Heterophyllum a rare medicinal plant of himalayan region. international journal of pharma and bio sciences, 2015, vol. 6, no. 2, p. P194–P200. .
Composition #8: Singh, K., Saloni, S., Shalini. Phytochemical screening and TLC profiling of different extracts of leaves, roots and stem of Aconitum Heterophyllum a rare medicinal plant of himalayan region. international journal of pharma and bio sciences, 2015, vol. 6, no. 2, p. P194–P200. .
Composition #9: Singh, K., Saloni, S., Shalini. Phytochemical screening and TLC profiling of different extracts of leaves, roots and stem of Aconitum Heterophyllum a rare medicinal plant of himalayan region. international journal of pharma and bio sciences, 2015, vol. 6, no. 2, p. P194–P200. .
Composition #10: Nagarajan, M., Kuruvilla, Gina R., Kumar, K Subrahmanya., Venkatasubramanian, Padma. Abhava pratinidhi dravya: A comparative phytochemistry of Ativisha, Musta and related species. . journal of ayurveda and integrative medicine, 2015, vol. 6, no. 1, p. 53–63. DOI: 10.4103/0975-9476.146550. [DOI link]
Composition #11: Kumar, Varun., Malhotra, Nikhil., Pal, Tarun., Chauhan, Rajinder Singh. Molecular dissection of pathway components unravel atisine biosynthesis in a non-toxic Aconitum species, A. heterophyllum Wall. . 3 biotech, 2016, vol. 6, no. 1, p. 106–106. DOI: 10.1007/s13205-016-0417-7. [DOI link]
Composition #12: Nisar, Muhammad., Obaidullah., Ahmad, Manzoor., Wadood, Noreen., Lodhi, Muhammad Arif., Shaheen, Farzana., Choudhary, M. Iqbal. New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors . journal of enzyme inhibition and medicinal chemistry, 2009, vol. 24, no. 1, p. 47–51. DOI: 10.1080/14756360801906202. [DOI link]
Composition #13: Jaiswal, Yogini., Liang, Zhitao., Ho, Alan., Wong, LaiLai., Yong, Peng., Chen, Hubiao., Zhao, Zhongzhen. Distribution of toxic alkaloids in tissues from three herbal medicine Aconitum species using laser micro-dissection, UHPLC-QTOF MS and LC-MS/MS techniques . phytochemistry, 2014, vol. 107, p. 155–174. DOI: 10.1016/j.phytochem.2014.07.026. [DOI link]
Composition #14: Malhotra, Nikhil., Kumar, Varun., Sood, Hemant., Singh, Tiratha Raj., Chauhan, Rajinder Singh. Multiple genes of mevalonate and non-mevalonate pathways contribute to high aconites content in an endangered medicinal herb, Aconitum heterophyllum Wall . phytochemistry, 2014, vol. 108, p. 26–34. DOI: 10.1016/j.phytochem.2014.08.025. [DOI link]
Endpoint study #1: Ankita Bachhawat, J., Shihabudeen, M.S., Thirumurugan, K. Screening of Fifteen Indian ayurvedic plants for alpha-glucosidase inhibitory activity and enzyme kinetics. international journal of pharmacy and pharmaceutical sciences, 2011, vol. 3, no. SUPPL. 4, p. 267–274. .