EFSA Compendium of Botanicals

Draft - work in progress

Achillea abrotanoides (Vis.)Vis.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 12
Number of processed references:: 4

Compositions

#1: Guaianolides in aerial parts #2: 1,8-cineole in aerial parts #3: alpha-thujone in aerial parts #4: beta-thujone in aerial parts #5: Camphor in aerial parts #6: Myrcene in aerial parts #7: 1,8-cineole in aerial parts #8: Alpha-thujone in aerial parts #9: Pinocarvone in aerial parts #10: Beta-thujone in aerial parts #11: 1.8-cineole in leaves #12: Beta-thujone in leaves #13: Camphor in leaves

Endpoint Studies

Genotoxicity

Composition #1: Stefanović, M., Djermanović, V., Gorunvić, M., Djermanović, M., Macura, S., Milosavljević, S. Sesquiterpene lactones from Achillea abrotanoides. phytochemistry, 1989, vol. 28, no. 6, p. 1765–1767. DOI: 10.1016/S0031-9422(00)97843-9. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

CHCl3
Substance:

guaianolides (RF-00010821-PAR)
Additional substance description:

desacetoxymatricarin, desacetyl matricarin and 1-beta, 10-beta-epoxydesacetoxymatricarin
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Guaianolides in aerial parts

Composition #2: Hanlidou, E., Kokkini, S., Kokkalou, E. Volatile constituents of Achillea abrotanoides in relation to their infrageneric variation. biochemical systematics and ecology, 1992, vol. 20, no. 1, p. 33–40. DOI: 10.1016/0305-1978(92)90070-T. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8.47-18.5
Internal remarks:

1,8-cineole in aerial parts

Composition #3: Hanlidou, E., Kokkini, S., Kokkalou, E. Volatile constituents of Achillea abrotanoides in relation to their infrageneric variation. biochemical systematics and ecology, 1992, vol. 20, no. 1, p. 33–40. DOI: 10.1016/0305-1978(92)90070-T. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-thujone (RF-00003676-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.3-35.4
Internal remarks:

alpha-thujone in aerial parts

Composition #4: Hanlidou, E., Kokkini, S., Kokkalou, E. Volatile constituents of Achillea abrotanoides in relation to their infrageneric variation. biochemical systematics and ecology, 1992, vol. 20, no. 1, p. 33–40. DOI: 10.1016/0305-1978(92)90070-T. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

beta-thujone (RF-00003712-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3-10.2
Internal remarks:

beta-thujone in aerial parts

Composition #5: Hanlidou, E., Kokkini, S., Kokkalou, E. Volatile constituents of Achillea abrotanoides in relation to their infrageneric variation. biochemical systematics and ecology, 1992, vol. 20, no. 1, p. 33–40. DOI: 10.1016/0305-1978(92)90070-T. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(-)-camphor (RF-00003469-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.26-14.2
Internal remarks:

Camphor in aerial parts

Composition #6: Chalchat, J.-C., Petrovic, S.D., Maksimovic, Z.A., Gorunovic, M.S. Aromatic plants of yugoslavia. III. Chemical composition of essential oils of achillea abrotanoides (Vis.) Vis., A. Clypeolata Sibth. & Sm., A. depressa Janka and A. Stricta Schleicher et Koch. journal of essential oil research, 2005, vol. 17, no. 5, p. 549–552. DOI: 10.1080/10412905.2005.9698991. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.2
Internal remarks:

Myrcene in aerial parts

Composition #7: Chalchat, J.-C., Petrovic, S.D., Maksimovic, Z.A., Gorunovic, M.S. Aromatic plants of yugoslavia. III. Chemical composition of essential oils of achillea abrotanoides (Vis.) Vis., A. Clypeolata Sibth. & Sm., A. depressa Janka and A. Stricta Schleicher et Koch. journal of essential oil research, 2005, vol. 17, no. 5, p. 549–552. DOI: 10.1080/10412905.2005.9698991. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

11.3
Internal remarks:

1,8-cineole in aerial parts

Composition #8: Chalchat, J.-C., Petrovic, S.D., Maksimovic, Z.A., Gorunovic, M.S. Aromatic plants of yugoslavia. III. Chemical composition of essential oils of achillea abrotanoides (Vis.) Vis., A. Clypeolata Sibth. & Sm., A. depressa Janka and A. Stricta Schleicher et Koch. journal of essential oil research, 2005, vol. 17, no. 5, p. 549–552. DOI: 10.1080/10412905.2005.9698991. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

alpha-thujone (RF-00003676-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.9
Internal remarks:

Alpha-thujone in aerial parts

Composition #9: Chalchat, J.-C., Petrovic, S.D., Maksimovic, Z.A., Gorunovic, M.S. Aromatic plants of yugoslavia. III. Chemical composition of essential oils of achillea abrotanoides (Vis.) Vis., A. Clypeolata Sibth. & Sm., A. depressa Janka and A. Stricta Schleicher et Koch. journal of essential oil research, 2005, vol. 17, no. 5, p. 549–552. DOI: 10.1080/10412905.2005.9698991. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

pinocarvone (RF-00003547-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

15.6
Internal remarks:

Pinocarvone in aerial parts

Composition #10: Chalchat, J.-C., Petrovic, S.D., Maksimovic, Z.A., Gorunovic, M.S. Aromatic plants of yugoslavia. III. Chemical composition of essential oils of achillea abrotanoides (Vis.) Vis., A. Clypeolata Sibth. & Sm., A. depressa Janka and A. Stricta Schleicher et Koch. journal of essential oil research, 2005, vol. 17, no. 5, p. 549–552. DOI: 10.1080/10412905.2005.9698991. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

beta-thujone (RF-00003712-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

16.8
Internal remarks:

Beta-thujone in aerial parts

Composition #11: Bicchi, C., Frattini, C., Cantamessa, L., Poggio, L. On the composition of Achillea abrotanoides (Vis.) Vis. essential oil. flavour and fragrance journal, 1988, vol. 3, no. 3, p. 101–104. DOI: 10.1002/ffj.2730030302. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

18.5
Internal remarks:

1.8-cineole in leaves

Composition #12: Bicchi, C., Frattini, C., Cantamessa, L., Poggio, L. On the composition of Achillea abrotanoides (Vis.) Vis. essential oil. flavour and fragrance journal, 1988, vol. 3, no. 3, p. 101–104. DOI: 10.1002/ffj.2730030302. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

beta-thujone (RF-00003712-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10.2
Internal remarks:

Beta-thujone in leaves

Composition #13: Bicchi, C., Frattini, C., Cantamessa, L., Poggio, L. On the composition of Achillea abrotanoides (Vis.) Vis. essential oil. flavour and fragrance journal, 1988, vol. 3, no. 3, p. 101–104. DOI: 10.1002/ffj.2730030302. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

hydrodistillation
Substance:

(-)-camphor (RF-00003469-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.2
Internal remarks:

Camphor in leaves